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CHIP-BCIS3 @CHIP_BCIS3

UK investigator-led multicentre prospective RCT on efficacy & safety of LV unloading in high-risk PCI. Funded by @NIHRresearch; @kingscardio @CTU_LSHTM @bcis_uk lshtm.ac.uk/chip-bcis3 London, UK Joined October 2020
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CHIP-BCIS3 @CHIP_BCIS3

a week ago

🗞️Our latest newsletter is out now! Q1 (Jan-Mar) 2024 recruitment has been incredible and we've now exceeded 200 participants! Outstanding work to all sites who have helped us achieve this special milestone. 🙌 Onwards and upwards for April and beyond!💪

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Matt Ryan @DrMattRyan

2 weeks ago

In @REVIVED_BCIS2, PCI did not prolong life in patients with ischemic LV dysfunction. But what about symptoms? Our detailed analysis of health status and quality of life out this week in JACC: Heart Failure. jacc.org/doi/10.1016/j.…

CHIP-BCIS3 retweeted
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Davide Capodanno @DFCapodanno

2 weeks ago

After 10 years to complete it, the DanGer-SHOCK trial showed that the routine use of a microaxial flow pump with standard care in the treatment of patients with STEMI-related cardiogenic shock led to a lower risk of death from any cause at 180 days than standard care alone. The…

CHIP-BCIS3 retweeted
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BCIS-4 Trial @BCIS4Trial

3 months ago

Welcome to the @BCIS4Trial X page. This study is funded by the National Institute of Health Research (NIHR) [HTA (NIHR155123]. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care

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CHIP-BCIS3 @CHIP_BCIS3

2 months ago

🙌2nd patient randomised at Musgrove Park Hospital @SomersetFT @MoSahebjalal. Fantastic work!

CHIP-BCIS3 retweeted
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CircInterventions @CircIntv

2 months ago

Is there a role for left ventricular unloading in high-risk PCI? Design and rational of CHIP-BCIS3 RCT #cardiotwitter #AHAJournals @ncurzen @DrPeterOKane @SaadEzad @ford1102 @divaka_perera ahajrnls.org/48HES83

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CHIP-BCIS3 @CHIP_BCIS3

2 months ago

💥Another record-breaking month for recruitment in Feb. 🗞️Catch all the latest updates in our March edition out now! 👇 @NIHRresearch @kingscardio @CTU_LSHTM @BCIS_uk

CHIP-BCIS3 retweeted
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Cardiac Research @UKheartresearch

2 months ago

3. Periprocedural MI (ppMI) only considered if “more important” clinical outcomes have not occurred in pairwise comparison. 4. ppMI definition specific to pre-procedure values and trends. #WinRatio comparison considers size of infarct. @CTU_LSHTM @DrMattRyan @divaka_perera

CHIP-BCIS3 retweeted
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Cardiac Research @UKheartresearch

2 months ago

1. It uses a hierarchical composite outcome that ranks clinical events in order of importance to the patient. 2. The incidence of this hierarchy in each patient assigned to LV unloading will be compared with every patient in the standard of care arm using a #WinRatio

CHIP-BCIS3 retweeted
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Cardiac Research @UKheartresearch

2 months ago

The paper in @CircIntv describes how the @CHIP_BCIS3 trial uses novel methodology to optimise the chances of finding a definitive answer to this important clinical question: does elective LV unloading during high-risk PCI reduce major adverse CV events? bit.ly/4bV3VHu

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Matt Ryan @DrMattRyan

2 months ago

The paper in @CircIntv describes how the @CHIP_BCIS3 trial uses novel methodology to optimise the chances of finding a definitive answer to this important clinical question: does elective LV unloading during high-risk PCI reduce major adverse CV events? bit.ly/4bV3VHu

CHIP-BCIS3 retweeted
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Matt Ryan @DrMattRyan

2 months ago

Rationale and design of the CHIP-BCIS3 randomized controlled trial: LV unloading in high-risk PCI. Just published in @circ CVINT. ➡️ historical challenges of trials in MCS ➡️innovative design and ideal population to deliver a definitive trial bit.ly/4bV3VHu

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CHIP-BCIS3 @CHIP_BCIS3

2 months ago

CHIP-BCIS3 protocol paper out today in @circ CVINT. Thanks to all @CHIP_BCIS3 committees, investigators, research staff, and patients. @divaka_perera @DrMattRyan @NIHRresearch @kingscardio @GSTTresearch @CTU_LSHTM

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Matt Ryan @DrMattRyan

2 months ago

CHIP-BCIS3 protocol paper out today in @circ CVINT. Thanks to all @CHIP_BCIS3 committees, investigators, research staff, and patients. @divaka_perera @DrMattRyan @NIHRresearch @kingscardio @GSTTresearch @CTU_LSHTM https://t.co/FkfvARRUX2

CHIP-BCIS3 retweeted
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Divaka Perera @divaka_perera

2 months ago

Thanks to our amazing network of @CHIP_BCIS3 @BCIS_uk investigators, trial management group, oversight committees, funders and all the patients who have volunteered, we are firmly on track to complete the trial and answer important questions about LV unloading in high-risk PCI!

DrMattRyan Profile Picture

Matt Ryan @DrMattRyan

2 months ago

Thanks to our amazing network of @CHIP_BCIS3 @BCIS_uk investigators, trial management group, oversight committees, funders and all the patients who have volunteered, we are firmly on track to complete the trial and answer important questions about LV unloading in high-risk PCI!

CHIP-BCIS3 retweeted
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Lynn Laidlaw (she/her) @lynn_laidlaw

2 months ago

I have learned about the conduct of clinical trials as a result of being involved in CHIP-BCIS3. Best thing has been building relationships and collaborating with Matt and all the Co I’s. People undergoing high risk PCI deserve evidence based interventions

DrMattRyan Profile Picture

Matt Ryan @DrMattRyan

2 months ago

I have learned about the conduct of clinical trials as a result of being involved in CHIP-BCIS3. Best thing has been building relationships and collaborating with Matt and all the Co I’s. People undergoing high risk PCI deserve evidence based interventions

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CHIP-BCIS3 @CHIP_BCIS3

2 months ago

🚀We're flying along this month with 10 enrolled so far and not even half way through February! 🏏Can we hit a double century by March?🎯 Special shoutout to team @NHSResCornwall @tamas_ungvari and co for their 1st patient enrolled. Keep up the incredible work all!💪

CHIP-BCIS3 retweeted
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Holly @hollymorgs

3 months ago

Excellent run through of the Win ratio from the legend that is @TimCClayton, to kick off the #BCISACI "Tik Tok talks" ⏰️ ➡️ Hierarchical end point system, increasingly used in cardiovascular trials including the ongoing @CHIP_BCIS3🫀📈

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