D.B.R.K Gupta Udatha @DBRK_Gupta
Accelerating Digital Innovations no.linkedin.com/in/guptaudatha Oslo, Norway Joined May 2012-
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🐟🪰 Separated by evolution, connected by the same developmental code. 🔗Digital cousins: Simultaneous optimization of one model for BMP signaling in distant relatives reveals essential core. DOI: doi.org/10.1016/j.csbj… 📚CSBJ: csbj.org #Evolution @CSB_Journal
🩻 AI isn’t here to replace radiologists — it’s here to write their first draft. 🔗 Hybrid framework for automated generation of mammography radiology reports. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #Radiology #DigitalHealth #Mammography #AI @CSB_Journal
🔗 Developing foundations for biomedical knowledgebases from literature using large language models – A systematic assessment. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #LargeLanguageModels #BiomedicalAI #Bioinformatics #AI #DigitalHealth #MedAI @CSB_Journal
🧩 The future of drug discovery may depend on how well we understand PROTAC-driven protein partnerships. 🔗Mapping the energy landscape of PROTAC-mediated protein-protein interactions. DOI: doi.org/10.1016/j.csbj… 📚CSBJ: csbj.org #StructuralBiology @CSB_Journal
🔗 Class-agnostic annotation of small RNAs balances sensitivity and specificity in diverse organisms. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #RNA #Bioinformatics #Genomics #ComputationalBiology #Transcriptomics #MolecularBiology #Epigenetics, @CSB_Journal
🧠 Can large language models (LLMs) accurately classify liver lesions from MRI reports? 🔗 Leveraging large language models for accurate classification of liver lesions from MRI reports. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #MedicalImaging @CSB_Journal
🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance? 🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #Biophysics #CryoEM @CSB_Journal
🦷 What if your dentist could see more with less radiation? 🔗 Trajectory generation for ROI expansion in dental CBCT imaging: An out-of-FOV ROI annotation guided arc scan-based approach. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ Smart Hospital: csbj.org/smarthospital @CSB_Journal
🧬 Will smaller, lighter AI models democratize computational biology? 🔗 Small, open-source text-embedding models as substitutes to OpenAI models for gene analysis. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #Genomics #AI #LLMs #Bioinformatics, @CSB_Journal
🔗 Learning the language of plant immunity: opportunities and challenges for AI-assisted modelling of fungal effector x host protein complexes. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #PlantImmunity #PlantPathology #MolecularBiology #AgriTech @CSB_Journal
🧬 Could the key to better genomic models lie in how we “read” sequences? 🔗 Tokenization and deep learning architectures in genomics: A comprehensive review. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #Genomics #DeepLearning #AIinBiology #DNA @CSB_Journal
🔗 Bridging prediction and reality: Comprehensive analysis of experimental and AlphaFold 2 full-length nuclear receptor structures. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #AlphaFold2 #DrugDiscovery #StructuralBiology #NuclearReceptors @CSB_Journal
🤖 Can algorithms outsmart evolution to create therapies humans never imagined? 🔗 Computational nanobody design through deep generative modeling and epitope landscape profiling. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #AntibodyEngineering @CSB_Journal
🔗 Phasor-FLIM and SHG imaging for quantitative analysis of lung cancer autofluorescence. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ Quantum Biology and Biophotonics: csbj.org/qbio #CancerDiagnostics #Biophotonics #OpticalImaging #BiomedicalOptics #Bioimaging @CSB_Journal
🔗 A single HIIT session does not alter blood sphingolipid levels in healthy young adults: The SphingoHIIT randomized controlled trial. DOI: doi.org/10.1016/j.csbj… 📚CSBJ: csbj.org #SportsMedicine #Metabolomics #Exercise #FitnessResearch #Wellbeing @CSB_Journal
🔗 Integrate & balance aspects for safe and sustainable innovation: Needs analysis on SSbD categories and product development stage requirements to cover the entire life cycle. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ Nanoscience & Advanced Materials: csbj.org/nano #SSbD
🔗 SbD4Skin by EosCloud: Integrating multi-view molecular representation for predicting skin sensitization, irritation, and acute dermal toxicity. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ Nanoscience and Advanced Materials: csbj.org/nano #Toxicology #CSBJNAM @CSB_Journal
🔗 Cybersecurity requirements for medical devices in the EU and US - A comparison and gap analysis of the MDCG 2019–16 and FDA premarket cybersecurity guidance. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ Smart Hospital: csbj.org/smarthospital #MedicalDevices #FDA #EU @CSB_Journal
🔗 Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy. DOI: doi.org/10.1016/j.csbj… 📚 CSBJ Smart Hospital: csbj.org/smarthospital #Genomics #Polypharmacy #Pharmacogenomics #MedTech
🧪 Could digital modeling redefine how we grow CHO cells for biologics? 🔗 Wheels turning: CHO cell modeling moves into a digital biomanufacturing era. @CSB_Journal, DOI: doi.org/10.1016/j.csbj… 📚 CSBJ: csbj.org #Biomanufacturing #CHOCells #DigitalTwin #SysBio

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