Haseeb Rahman @DrHaseebRahman1
NIHR Academic Clinical Lecturer & Interventional Cardiology Fellow, St Thomas’ Hospital. Research interest in coronary physiology and microvascular angina. London, England Joined August 2019-
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Really interesting results and external validation of previous work by #KCL team. 🔗ahajournals.org/doi/10.1161/JA… ➡️Coronary slow flow not associated with abnormal CFR or microvascular resistance. @divaka_perera @DrHaseebRahman1 @AishSinha1 @UKheartresearch
Really interesting results and external validation of previous work by #KCL team. 🔗ahajournals.org/doi/10.1161/JA… ➡️Coronary slow flow not associated with abnormal CFR or microvascular resistance. @divaka_perera @DrHaseebRahman1 @AishSinha1 @UKheartresearch https://t.co/QeeiWQ2NBX
HFpEF is a growing healthcare burden, and CMD is prevalent among sufferers. We discuss this association + the gaps in evidence in our review in AHJ+: 🫀CMD as part of the pro-inflammatory paradigm in HFpEF. ➡️CMD as a pathophysiological driver. bit.ly/CMD-HFpEF
Rationale and design of the CHIP-BCIS3 randomized controlled trial: LV unloading in high-risk PCI. Just published in @circ CVINT. ➡️ historical challenges of trials in MCS ➡️innovative design and ideal population to deliver a definitive trial bit.ly/4bV3VHu
💥When assessed against the reference standard of comprehensive coronary physiology, ischemia on EST had 100% specificity for an underlying vasomotor disorder. 💥These findings challenge the current dogma and may lead to a paradigm shift in the evaluation of patients with CCS.
💥When assessed against the reference standard of comprehensive coronary physiology, ischemia on EST had 100% specificity for an underlying vasomotor disorder. 💥These findings challenge the current dogma and may lead to a paradigm shift in the evaluation of patients with CCS.
The authors of a recent study published in #JACC conclude that in patients w/ ANOCA, ischemia on EST is highly specific of an underlying ischemic substrate. These findings challenge the traditional belief that EST has a high false positive rate. bit.ly/3vv9ifS
In patients with #ANOCA, ischemia during exercise #ECG stress testing was highly specific for coronary microvascular dysfunction bit.ly/41TKydp #JACC @AishSinha1 @DrHaseebRahman1 @divaka_perera @UKheartresearch
#ICYMI #OriginalResearch: In the #ChaMP-CMD trial of ANOCA patients, invasive CFR suggestive of coronary microvascular disease identified patients who derived greater response to anti-ischemic therapy @divaka_perera @DrOzanDemir @achir76 #AHAJournals
➡️Rethinking False Positive ETT by Assessing Coronary Microvascular Function. 🎯In patients with ANOCA, ischemia on ETT was highly specific of an underlying ischemic substrate. 🎯Comprehensive coronary physiology 🔗jacc.org/doi/10.1016/j.… @BCIS_uk @PCRonline @JACCJournals
➡️Rethinking False Positive ETT by Assessing Coronary Microvascular Function. 🎯In patients with ANOCA, ischemia on ETT was highly specific of an underlying ischemic substrate. 🎯Comprehensive coronary physiology 🔗jacc.org/doi/10.1016/j.… @BCIS_uk @PCRonline @JACCJournals https://t.co/XZ76HYhhKL
Do Myocardial Bridges Cause Ischemia? Characterising Mechanisms of Ischemia in Patients with Myocardial Bridges. A simultaneous publication to @AHAMeetings #AHA2023. ahajournals.org/doi/abs/10.116… @divaka_perera @AishSinha1 @DrHaseebRahman1 @UKheartresearch @AHAScience @CircAHA
ChaMP-CMD trial results just published in @CircAHA @AishSinha1 @divaka_perera @The_MRC @kingscardio ➡️ Patients with CMD (low CFR) benefit from anti-ischaemic therapy but not those with a normal CFR ➡️ CFR establishes diagnosis AND guides treatment. doi.org/10.1161/CIRCUL…
🏴☠️CMD-HFpEF is a prevalent endotype of HFpEF ❌However, its pathophysiology remains incompletely understood ✅We discuss impaired lusitropy and subendocardial ischemia as the potential link between CMD and HFpEF bit.ly/3Pu66ro
5-year follow up of DEFINE-FLAIR (iFR vs FFR-guided revascularisation) presented by @JEscaned #EuroPCR2023 ➡️ MACE higher in iFR arm (HR 1.18; CI 0.99 - 1.41, p=0.07) ➡️ All-cause death 3% higher in iFR arm (HR 1.51; CI 1.22 - 2.90) ➡️ Difference driven by CV death
#CTOPCI - NSTEMI from failing vein graft - stabilised with PCI to VG-RCA, then returned for elective PCI to native RCA - facilitated ADR #gsttcto @DrHaseebRahman1 @AKaloger33 @AntonisPavlidi3
Coronary Slow Flow Is Not Diagnostic of Microvascular Dysfunction in Patients with Angina and Unobstructed Coronary Arteries #AHAJournals ahajrnls.org/3Iwq5DU
First-ever, first-author paper in @JAHA_AHA, demonstrating that coronary slow flow ≠ microvascular dysfunction in patients with angina and normal angiograms. 🔗: ahajournals.org/doi/full/10.11… Blessed to have mentors like @AishSinha1, @DrHaseebRahman1 and @divaka_perera!
First-ever, first-author paper in @JAHA_AHA, demonstrating that coronary slow flow ≠ microvascular dysfunction in patients with angina and normal angiograms. 🔗: ahajournals.org/doi/full/10.11… Blessed to have mentors like @AishSinha1, @DrHaseebRahman1 and @divaka_perera!
➡️ Angiographic estimations of flow and microvascular resistance do not correlate with invasive references ➡️ “slow flow” does not correlate to microvascular or endothelial dysfunction Read more about our latest findings at bit.ly/3Z7aAbd
Great talk by Prof @divaka_perera on: ➡️Measuring Coronary Flow in the Cath Lab: Why and How 🔗to📺: opci.live/opci-manager/e… 🔗to📜: jacc.org/doi/10.1016/j.… @OPCILive Journal Club @JWMoses @ESHLOF @mmamas1973 @DrHaseebRahman1 @drTPH @sbrugaletta @LermanAmir @ColletCarlos
Check out this week's Journal Club episode featuring a conversation with @divaka_perera on "Measuring Coronary Flow in the Cath Lab: Why and How” opci.live/opci-journal-c… @ziadalinyc @djc795 @DrAllenJ @CathElectroSurg @JWMoses @ESHLOF
@OPCILive @divaka_perera @ziadalinyc @djc795 @DrAllenJ @CathElectroSurg @JWMoses @ESHLOF Super cool session! 👍🏻
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Really interesting results and external validation of previous work by #KCL team. 🔗ahajournals.org/doi/10.1161/JA… ➡️Coronary slow flow not associated with abnormal CFR or microvascular resistance. @divaka_perera @DrHaseebRahman1 @AishSinha1 @UKheartresearch
Is coronary slow-flow a reliable angiographic surrogate for wire-based physiology testing in INOCA? To be presented at #ACC24 and published simultaneously: ahajournals.org/doi/10.1161/CI… @NSmilowitzMD @AHausvater #AHAJournals
INOCA in Long COVID syndrome. First evidence, most likely due to affinity of SARS-CoV-2 for endothelial cells. Stratified Tx improves angina. Just published in JACC Intv. Access: authors.elsevier.com/a/1iubV_i2X-Os…. @PCRonline @IIS_IdISSC @unicomplutense @InocaInternati1 @JACCJournals
@dr_benoy_n_shah @djc795 @kaulcsmc @SachinGoelMD @SVRaoMD @drandrewsharp @Ramku14 @Almanfi_Cardio @mmamas1973 @iamritu ✈️ from #ACC2024 & agree 👍🏻 to see a device study in the PCI yield a positive result - it’s especially important because Cardiogenic shock has a such terrible prognosis- need to discuss locally @UHD_NHS how we can apply this strategy - will High risk pci 🇬🇧 same @CHIP_BCIS3 🤔
HFpEF is a growing healthcare burden, and CMD is prevalent among sufferers. We discuss this association + the gaps in evidence in our review in AHJ+: 🫀CMD as part of the pro-inflammatory paradigm in HFpEF. ➡️CMD as a pathophysiological driver. bit.ly/CMD-HFpEF
Delighted to share our paper in @Open_HeartBMJ - a meta-analysis on the Comparison of troponin and natriuretic peptides in Takotsubo syndrome and acute coronary syndrome by @LiamCouch with colleagues across @RBandH @RDMOxford @Kings_BHFCentre openheart.bmj.com/content/11/1/e…
Thanks to our amazing network of @CHIP_BCIS3 @BCIS_uk investigators, trial management group, oversight committees, funders and all the patients who have volunteered, we are firmly on track to complete the trial and answer important questions about LV unloading in high-risk PCI!
Rationale and design of the CHIP-BCIS3 randomized controlled trial: LV unloading in high-risk PCI. Just published in @circ CVINT. ➡️ historical challenges of trials in MCS ➡️innovative design and ideal population to deliver a definitive trial bit.ly/4bV3VHu
Rationale and design of the CHIP-BCIS3 randomized controlled trial: LV unloading in high-risk PCI. Just published in @circ CVINT. ➡️ historical challenges of trials in MCS ➡️innovative design and ideal population to deliver a definitive trial bit.ly/4bV3VHu
🔍 Curious about the optimal OAC post #TAVR? 🫀 ⚡️Tune in to interview with @BashirAlaour, lead author of today's publication in @JACCJournals comparing VKA vs DOAC s/p TAVR 🔖Get the scoop here: jacc.org/doi/10.1016/j.… ▪️Don't miss the comments below for key insights &…
In INOCA/CMD studies, intracoronary electrocardiogram (icECG) can be straightforwardly used as an objective real-time marker of reversible ischemia during hyperaemia. A simple alligator clip + standard wires suffice for the set-up. Article ->pubmed.ncbi.nlm.nih.gov/38278503/ @ahmettascor
Summarising the Education Forum Revascularisation in Ischaemic Cardiomyopathy and why you should attend, @divaka_perera said: "Everything you need to know about managing ischaemic cardiomyopathy in light of the REVIVED and STICH trials." Register here: bit.ly/47N8rEC
MIRACLE2 score & post-#OHCA outcomes! Stronger associations (OR: 2.23) than downtime, zero flow, low flow, & superior discrimination (AUC: 0.877)! Positive predictive value of MIRACLE2 (score ≥5) beats current RCT criteria bit.ly/45UEC4p #JACCINT #ACCFIT #CardioTwitter
➡️TAVI to Treat Degenerated Aortic, Mitral and Tricuspid Bioprosthesis 🎯Review of evidence & procedural considerations for using TAVI device in managing degenerated aortic, mitral, or tricuspid prosthesis. 🔗mdpi.com/2077-0383/13/2… @PCRonline @BCIS_uk @EssexCTC @ImperialNHS
✍️Excellent editorial and podcast discussing the history of exercise testing in the context of new research! 🫀Could this be a revival of exercise testing in patients with angina? 💥Should ALL non-invasive modalities be re-evaluated against this contemporary ref standard?
💥When assessed against the reference standard of comprehensive coronary physiology, ischemia on EST had 100% specificity for an underlying vasomotor disorder. 💥These findings challenge the current dogma and may lead to a paradigm shift in the evaluation of patients with CCS.
The authors of a recent study published in #JACC conclude that in patients w/ ANOCA, ischemia on EST is highly specific of an underlying ischemic substrate. These findings challenge the traditional belief that EST has a high false positive rate. bit.ly/3vv9ifS
An important study for INOCA patients, shedding new light on a readily available, non invasive test for INOCA! 😃 jacc.org/doi/10.1016/j.… INOCAInternational.com
In patients with #ANOCA, ischemia during exercise #ECG stress testing was highly specific for coronary microvascular dysfunction bit.ly/41TKydp #JACC @AishSinha1 @DrHaseebRahman1 @divaka_perera @UKheartresearch
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