Elrond @ElrondBio
🪞 @axialxyz Joined January 2022-
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NK Cells and Curing Cancer with Nina Horowitz youtube.com/watch?v=Wte5Wb…
Antibody therapeutics have become a major class of biologics used to treat a wide range of diseases, particularly cancer: 1. Innovation in antibody formats and engineering is enabling improved efficacy and safety
"I was taught that the immune system was incapable of recognizing cancer because cancers are comprised almost entirely of the same substances as normal tissues. The immune system is trained to avoid attacking ‘self’." - Edgar Engleman
Adimab model for RNA RNA therapeutics are beginning to have repeatable success in the clinic. With RNAi taking the lead in terms of approvals. However, IP for chemical modifications, delivery, formulation are becoming (temporary) barriers for new entrants.
Glycobiology in the clinic Glycans decorate every cell in the body. As well as most proteins and most recently found on RNA. Advances in glycoproteomics/chemical biology has led to several drug candidates in the clinic targeting glycosylation.
"By asking a novel question that you don't know the answer to, you discover whether you can formulate a way of finding the answer, and you stretch your own mind, and very often you learn something new." - Walter Gilbert, Nobel Prize winner for inventing DNA sequencing
Comprehensive Mapping of Electrophilic Small Molecule-Protein Interactions in Human Cells from the Cravatt lab @scrippsresearch
What are digital twins? They are pioneered by Unlearn, a technology company using AI to transform clinical trials. Using digital twins to forecast health outcomes for individual patients and reduce the size of a well-powered placebo arm for randomized controlled trials (RCT)
Scientist Stories: Peter Schultz, Playing with the Molecules of Life youtube.com/watch?v=sjWlXb…
"Where I think we’ll be in 15 years is that machine learning will be an absolutely critical, pivotal shift—a paradigm shift in how we discover and develop medicines." - Daphne Koller, Founder and CEO of Insitro
Light-switchable transcription factors obtained by direct screening in mammalian cells led by Liyuan Zhu @LiyuanZhu7 from the Jared Toettcher @toettch lab
"Learning something new about the biological system both motivates and inspires me. And I see technology development as a facilitator to get that new understanding." - Viviana Gradinaru, Pioneer in optogenetics & gene therapies to study the human brain
The Specious Art of Single-Cell Genomics led by Tara Chari from the Lior Pachter @lpachter lab
In situ architecture of the ER–mitochondria encounter structure led by Michael Wozny @michael_wozny from the Wanda Kukulski @KukulskiWanda lab
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules led by Sigitas Mikutis @Sigi_Mikutis from the Konstantinos Tzelepis @TzelepisLab & Gonçalo Bernardes @gbernardes_chem labs
"The generous thing to do is to leave your name off the paper. I had a rule when I went to Merck in that I insisted my name never be on a publication." - Roy Vagelos, biotech legend and former CEO of Merck
Selective G protein signaling driven by substance P–neurokinin receptor dynamics led by Julian Harris from the Aashish Manglik @AashishManglik lab
Dicerna @DicernaPharma: - Founded in 2006 by Douglas Fambrough to develop RNAi drugs - Using their GalXC platform to conjugate RNA with GalNAc via a tetraloop - Widely collaborating with Eli Lilly, Novo, Roche, among others - Getting acquired by Novo Nordisk in 2021 for $3.3B
“I am a strong believer in people with complementary backgrounds working together. Sometimes just in the act of articulating what you are doing you get better ideas.” - David Baker, Professor at the University of Washington & Pioneer in de novo protein structure prediction
The PhD Place @ThePhDPlace
108K Followers 18K Following Empowering doctoral researchers through community 🎓 Weekly Guides @DoctoralStories 📚 Online writing group @AcWriClub ✍️ #AcademicTwitterVishwanath Upadhyay�.. @vishu272
2K Followers 5K Following PhD Scholar, Molecular Medicine, M.tuberculosis, Nontuberculous mycobacteria; BJP, sapiosexual, sports,whiskey & beer lover; Secularism, liberalism are scamsErmelinda Biedekapp @EBiedekapp58019
63 Followers 5K FollowingUmer Abdullah @m_umerabdullah
123 Followers 1K Following PhD student at @CityUHongKong | SCMP published bird photographerAna Lalinde @AnaLalinde71137
0 Followers 128 FollowingConnie @rowellconnie55
4K Followers 4K FollowingKenisha Machen @MacheKeni
64 Followers 5K FollowingFloy Cavrak @FCavrak92854
58 Followers 5K FollowingIris Heltzel @IrHeltz
30 Followers 5K FollowingAlyssa Spilski @spilski26354
85 Followers 5K FollowingJuliet Schnelder @JSchnelder97850
83 Followers 5K FollowingPrisha Kuehneman @PKuehneman19369
30 Followers 5K FollowingNestNinja @ninja_nest
1K Followers 3K Following "Navigating the real estate landscape one dream home at a time – join the journey! 🏠Mary J Harper @okinite
310 Followers 2K Following Chi Healing Energy ,Trading , Nature , Animals , Music , 528 Hz , Integrity . #GG33 #Gain28. https://t.co/tEcvER786PLittle Shell Kwe @aanjiniigikwe
3K Followers 3K Following *Actual* Little Shell Kwe - Enrolled member of the Montana #LittleShell Tribe 🦬🪶⚜️☘️ @MTLittleShellLavin Tyce @lavin_tyc
29 Followers 5K FollowingJodi Jordan @JodiJordan58138
112 Followers 3K FollowingSharice Gerondale @s_geronda
59 Followers 5K FollowingBriana Gormanous @gormanous99153
72 Followers 5K FollowingCorinne Krizek @CorinKriz
33 Followers 5K FollowingTanisha Anderson @TanishaA15913
66 Followers 3K FollowingSamara Vessel @SamaraVess
30 Followers 5K FollowingHayley Gron @HGron89813
27 Followers 5K FollowingNandhiji @nandhiji
156K Followers 171K Following Spiritual Leader | Yogi | Visionary | Leadership - Declaration of Consciousness 🪔 Author: Mastery of Consciousness | Musician | Artist | Keynote Speaker 🌊Prossy nabunje @Prossynabunje
37 Followers 565 Following God first, self-love, addicted to helping others, student.true BelieverApril Hasencamp @AHasenca
32 Followers 5K FollowingKatelynn Ma @katel_ma
43 Followers 5K FollowingAdelina Moorefield @AdeliMoorefiel
29 Followers 5K FollowingRosalívia @Thanis561371
2 Followers 728 Following Venha comigo na busca por oportunidades lucrativas no mercado digital. Transforme seu futuro! 💹💪Crypto Gee 🐉 $MON @joebaba7
47 Followers 342 FollowingSorrow @lepukne46273
3 Followers 440 Following I want to be in a unique relationship. https://t.co/wdtTUKdYmBMichelle @michelleparado6
193 Followers 3K FollowingBaseStarter @basestarterx
221 Followers 3K Following Content Creation and Sharing App, integrating with #AI #Web3 and #NFT techFabio Echegaray @fabioechegaray
210 Followers 605 Following Researcher in Biological systems, interested in the the question of how does complexity drive all their processes. Curated retweets and opinions are my own.Luis J. Castro-Vega @LuisJaimeCastr3
575 Followers 3K Following Physician scientist working at the Paris Brain Institute @ParisBrainInst. I am focused on uncovering the underlying mechanisms of tumor brain progression.Helal Noman @HelalNoman
51 Followers 1K Following Deputy Medco @MSF , Health Officer @ICRC , Field Manager @Int.Relief. MD, OncologyTom Zaplana @TomZpln
60 Followers 221 Following PhD student @GenoUMR_GM @CEA_jacob_ @UnivEvry in Synthetic Biology/Metabolic EngineeringDesigner Forid6 @designer_forid6
1K Followers 5K Following Hello! I am Faridul. Mainly I am a professional graphic designer I always make a design with my creativity and with my long-time professional experience.Bruno Cabral Braga @cabral_bb
113 Followers 334 Following Researcher on chronic degenerative and metabolic diseases; Diabetes, cardiomyopathies and neurodegenerative disorders.Federal University of Rio de Janeiro @UFRJSharvari @Sharvari_msd
97 Followers 325 Following Research Associate II | VIR Biotechnology | ScM 2020 Molecular Microbiology and Immunology | Johns Hopkins Bloomberg School of Public HealthThe PhD Place @ThePhDPlace
108K Followers 18K Following Empowering doctoral researchers through community 🎓 Weekly Guides @DoctoralStories 📚 Online writing group @AcWriClub ✍️ #AcademicTwitterThe Struggling Scient.. @TheStrugglingS4
52K Followers 23K Following 🤩Science & PhD Life Podcast 🎙️Episodes 🤣PhD Memes 👕Science inspired Merch 📰PhD related BlogsHappy Researchers @hapyresearchers
61K Followers 1 Following Let us share our academic experiences, promote good mental health, and help each other. Run by @hgupta84 #happyresearchersAcademic Chatter™ @AcademicChatter
273K Followers 981 Following Join #AcademicChatter for support & community. Team: @waterlego @Heather_RoseW.PhD_Genie @PhD_Genie
73K Followers 912 Following The PhD_Genie is here to support academics - from early career researchers to well established scholars. Operated by @IdoRosenzweig. #PhDgeniePhD Voice - Independe.. @PhDVoice
137K Followers 85K Following Amplifying the voices of PhD Students. Tag us with # or @PhDVoice. Runs @PostdocVoice. Free PhD Resources https://t.co/jKq1NNX0ch Independently RunDr Zoë Ayres @ZJAyres
83K Followers 22K Following Analytical Scientist 👩🔬 #AcademicMentalHealth advocate 🌱 Founder @academicvoices 💬 Author 📘 ADHDer 💚 'Furiously opinionated'🤭 she/her 🌈 Views my ownAcademic Mom, PhD @Momademia
35K Followers 479 Following Why choose between mom guilt and writing guilt when you can have both? Encouraging and connecting parents in academia. (she/her)Dr Meming @Dr_Meming
64K Followers 2K Following I spend more time making memes than doing research. Some would say it’s procrastination I would say it’s outreach.Edmund 💉 @EdmundOris
73K Followers 15K Following Twitter Growth Coach for Football Creators, Influencers, Podcasters & YouTubers. DM “Football” to grow & monetize your Twitter Audience in 30 days or less.Vishwanath Upadhyay�.. @vishu272
2K Followers 5K Following PhD Scholar, Molecular Medicine, M.tuberculosis, Nontuberculous mycobacteria; BJP, sapiosexual, sports,whiskey & beer lover; Secularism, liberalism are scamsJen Heemstra @jenheemstra
101K Followers 14K Following Professor and Chair of @WashUChem, proud member of @HeemstraLab. I'm a researcher, but I'm a #MentorFirst. Tweets mine.Samuel Ajayi 🇳🇬.. @SamdGreat01
189K Followers 1K Following PhD Candidate, Nuclear Physics, @floridastate University. Believer, Husband Father, Nigerian. Follow for tweets & youtube videos on scholarships/assistantshipsMaster Academia @MasterAcademia_
24K Followers 6K Following Master Academia shares knowledge and resources in five categories: 📚 Academic Skills 🎓 Career Advice 🌐 Networking Hacks 🔍 Research Essentials 📝 Thesis TipsPonyPilot @sharolynhill21
924 Followers 28 Following Failure is all I need and it's just as valuable to me as success. We only grow when I know how to do everything well No Porn #Shopping #BeachAdam Warmoth @AdamWarmoth
537 Followers 2K Following Product @ Archer. Formerly Anduril, Uber Elevate, Kitty Hawk, Stanford Mechatronics / Engineering Physics / Water PoloCarlson Cheng @carlsoncheng_
222 Followers 232 Following 23. looking for ai research role. llms & complex systems. prev dev @dao_hq @pixlxyz @visceralAI. dm’s open.Benjamin Gibbs @BGGthoughts
968 Followers 566 Following CEO @ReadyRobotics. Entrepreneur. Video gamer. Amateur scientist. Webcomic enthusiast. Avid student of the Singularity.Pierre Claver Niyonku.. @clavenkuru
47K Followers 44K Following Senior Journalist https://t.co/flDLbsdBql https://t.co/2VHavtGoM7 @RadiyoyacuVOA Bio: https://t.co/UV6WA8uC4S #InternationalJustice #Investigative #HumanRights #OSINT #FactCheckerCole Winans @colewinans
3K Followers 2K Following Software eng and Founder/CEO. Focused on AI and building great products. Built/sold Flyreel (acq'd by LexisNexis), ScoutIQ (acq'd by ThreeColts).xschmackx @xschmackx
204 Followers 922 Following PROTON is the CHOSEN ONE #Metallicus | $XPR | #MetalX | #WebAuthMack Burtlin \\\🐐 .. @theNoozDotXYZ
3K Followers 5K Following #YeshuaIsKing \\\ #PPC #FYMM #FYF #coutts4 📺https://t.co/xCByMCtqhVJean Pierre @JeanBarriosL
60 Followers 556 Following ME GUSTA ACTUAR HE TENIDO EL GUSTO DE PARTICIPAR EN VARIOS ELENCOS DE ACTUACIONLittle Shell Kwe @aanjiniigikwe
3K Followers 3K Following *Actual* Little Shell Kwe - Enrolled member of the Montana #LittleShell Tribe 🦬🪶⚜️☘️ @MTLittleShellMary J Harper @okinite
310 Followers 2K Following Chi Healing Energy ,Trading , Nature , Animals , Music , 528 Hz , Integrity . #GG33 #Gain28. https://t.co/tEcvER786Pjoannmay🌊🌊🌊 .. @joannmay91
13K Followers 13K Following #resist🟧#Ian writing, poetry, also on #substack Images are not mine.Carlo Cisco @CarloCisco
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682 Followers 542 Following We provide music catalog valuations and analysis.Marco Essomba @marcoessomba
33K Followers 36K Following Founder & CTO @blockapt | #CyberSecurity Expert | Top100 Global @GetEngati Influencer | Tweet #Tech #Startup #QuantumSecurity #AI #ML | 🇨🇲🇬🇧🇺🇸🇦🇺🇨🇦🇳🇿Nayrhit @NayrhitB
3K Followers 2K Following Kick-off AI-assisted SEO with Gush. https://t.co/6OA9qNrpv4 Backed by Lightspeed, Sparrow & Beenext.Arthur MacWaters @ArthurMacwaters
310 Followers 932 Following Princeton ➡️ McKinsey ➡️ YCombinator ➡️ Legion HealthMatthias Smith, CEO -.. @SBA_Matthias
26K Followers 6K Following CEO @ Pioneer Capital Advisory / I help business buyers using the SBA 7(a) loans get funded / $65 million closed in '23 / Aiming for $100 million in '24Trier and Company @triercompany
11K Followers 3K Following We're an award-winning Integrated Communications Agency for disruptive technology companies. We're passionate communications pros. #Content #PR #AgencyLifeNandhiji @nandhiji
156K Followers 171K Following Spiritual Leader | Yogi | Visionary | Leadership - Declaration of Consciousness 🪔 Author: Mastery of Consciousness | Musician | Artist | Keynote Speaker 🌊Shauryam Gupta @shauryam_gupta
313 Followers 144 Following CEO of https://t.co/mau2zANjyj | IIT Kharagpur | Engineering the most reliable Trading PlatformMazna A. @maznaa32
109 Followers 547 Following CEO at @steedstrat. Generated 7 figure ecom brands. Dedicated to empowering ambitious dads to stay calm when everyone panics & scaleup their businesses to 200X‼Danny G @the_danny_g
445 Followers 563 Following Mental health + AI founder—@LegionHealth (YC S21) | ex-MSFT | Join my startup and mental health journey and hear the lessons I've learned along the way.Chitra Nawbatt @chitranawbatt
10K Followers 2K Following Investor, entrepreneur & business builder, content creator. Multi-industry grad from tech, media @Reuters @BNNBloomberg @CTV, consulting, Wall Street. GratefulAnita M. Jovic @anijov
2K Followers 2K Following @InputOutputHK l Founder of Anax3 Ltd l Experience life and happiness - the goal is to die with memories, not dreams.Orville Skeete @carlnbp
2K Followers 4K Following I'm an internet marketer, making money with affiliate marketing online. I use free tools like Google that allows me to search the web & express myself blogging.Charityvest @Charityvest
666 Followers 891 Following Modern tax-deductible giving accounts for individuals + collaborative giving funds for communities. Stock & crypto giving. Support any charity. 🚀SVRHM 2022 Workshop @svrhm_workshop
690 Followers 930 Following 4th @NeurIPS2022 Workshop: Shared Visual Representations in Human and Machine Intelligence. Organizers: @ArtDeza @joshuacpeterson @apurvaratan @cocosci_labRosanne Liu @savvyRL
33K Followers 970 Following Cofounded & running @ml_collective. Host of Deep Learning Classics & Trends. Research at Google DeepMind. DEI/DIA Chair of ICLR & NeurIPS. Writing https://t.co/IbycyGfnDRDavid Pfau @pfau
22K Followers 1K Following Knowledge manifests itself in radiant dreams that shimmer like the wild sun Views are my own pfau at sigmoid dot social on 🦣 https://t.co/xqtVHHVI17 on 🦋Kosta Derpanis @CSProfKGD
48K Followers 198 Following #CS Associate Prof @YorkUniversity, #ComputerVision Scientist Samsung #AI, @VectorInst Faculty Affiliate, TPAMI AE, #CVPR2024/#ECCV2024 Publicity Co-chairShahab Bakhtiari @ShahabBakht
3K Followers 1K Following || assistant prof @UMontreal || leading the systems neuroscience and AI lab (SNAIL) || @Mila_Quebec || #NeuroAI || vision and learning in brains and machinesPeyman Milanfar @docmilanfar
68K Followers 263 Following Distinguished Scientist at Google Research. Computational Imaging, Machine Learning, and Vision. Tweets = personal opinions. May change or disappear over time.Jesse Pujji @jspujji
175K Followers 8K Following Tweets about building ambitious bootstrapped companies. Exited @ampush. Now building a $1B+ bootstrapped venture studio @GatewayXAndrea Orrego 🛋 @andreaOrrego
1K Followers 2K Following Founder @atelierhomeapp | Peruvian in Colorado 🇵🇪 | Mom of Norah & Ingle | Cory's other half | she/her | #casafam | @ganasvc scout | ArchitectAnt A @AntDX316
747 Followers 975 Following The real envy shouldn't be the richest of this world but the envy of those resting in a peaceful afterlife Until then, ASI needs to happen. Play @Planetside2Michal Takac (e/ia) @michaltakac
1K Followers 1K Following CEO @TheDimensionLab | @siml_ai (AI-driven simulations) | https://t.co/zEEcY4OCgg | @questspacesk | @parallelpoliske | ex-@decentraland | PhD in CyberneticsThomas Weinstein @konabiz
338 Followers 677 Following Web Dev, Creative Design, Marketing, Video & Music Production, Domainer, Organic Farming - Kona, Big IslandDavis Nunez @davisnunez_
241 Followers 174 Following Entrepreneur with passion for building and growing businesses | Co-Founder @ Solar Blaze (Bootstrapped from $0 to 7 Figures SaaS - exited)Nikolas Pareschi, MSF.. @Nikolaspareschi
12K Followers 261 Following Professional Gambler I try my best to control myself and only make bets with positive expectancy Former World Champion Trader - 2017Peter Shirley 🔮�.. @Peter_shirley
13K Followers 5K Following Former IndianaU, CornellU, UUtah, Rayscale, Nvidia, PurityLLC, Nvidia, now Activision #raytracing. #60fps #ViewsAreMyOwnMithu Storoni @MithuStoroni
4K Followers 2K Following MD, PhD. Author of “Hyperefficient” (Hachette) out on 17th September 2024🇺🇦 Dr. Stefanie.. @StefanieRobel
2K Followers 2K Following Author: Writing a book for research teams. Associate Professor Neuroscience. Helping PIs to create low-stress lab & mentoring systems @Glia_LeadershipMichael Recce @mlrecce
358 Followers 1K Following CEO of AlphaROC Inc. Scientist, engineer and investor. Tweets about books, science, data and math. Views expressed here are my own.Cosmic microwave background - radiation left over from the Big Bang - was discovered by Arno Penzias and Robert Wilson who initially thought it was just background interference in their measurements. Learn more: bit.ly/3VgO7cf
#OTD in 1897, British physicist J. J. Thomson presented his research on cathode rays culminating in the discovery of the electron. The announcement took place during an evening lecture at the Royal Institution in London. In 1906, he was awarded the #NobelPrize in Physics.
Let the Best Drug Win with Errik Anderson youtu.be/lZl9GwhOyYs
NK Cells and Curing Cancer with Nina Horowitz youtube.com/watch?v=Wte5Wb…
Antibody therapeutics have become a major class of biologics used to treat a wide range of diseases, particularly cancer: 1. Innovation in antibody formats and engineering is enabling improved efficacy and safety
Let the Best Drug Win with Errik Anderson youtu.be/lZl9GwhOyYs Errik is the CEO and Founder of Alloy Therapeutics. Founded in 2017, Alloy democratizes access to drug discovery platforms and services. In our conversation, we discuss Alloy's product offering and story
"I was taught that the immune system was incapable of recognizing cancer because cancers are comprised almost entirely of the same substances as normal tissues. The immune system is trained to avoid attacking ‘self’." - Edgar Engleman
Detecting chromatin interactions between and along sister chromatids with SisterC by Marlies E. Oomen, Adam K. Hedger, Jonathan K. Watts, and Job Dekker
Adimab model for RNA RNA therapeutics are beginning to have repeatable success in the clinic. With RNAi taking the lead in terms of approvals. However, IP for chemical modifications, delivery, formulation are becoming (temporary) barriers for new entrants.
LLMs to match patients with clinical trials Around a third of trials stop because of recruitment problems with >80% of them delayed due to them. LLMs have many possible use cases in biotech, but trials & anything that relies on texts seem like the best fits for scalable products
Locanabio @locanabio: - Founded in 2016 to develop RNA-targeting drugs - Focusing on neurodegenerative, neuromuscular & retinal diseases - With its CORRECTX platform relying on ADAR systems that modify RNA cleavage, splicing, gene replacement, translation enhancement & editing
Scientist Stories: Hans Clevers, Organoids and Drug Discovery youtube.com/watch?v=dGVmgT…
Vorasidenib An oral first-in-class dual IDH1/IDH2 inhibitor with efficacy in Phase III trials for IDH-mutant grade 2 gliomas, discovered through structure-based drug design (SBDD) of a prior mIDH inhibitor, developed by Agios and Servier
"Being a successful entrepreneur requires having an immense belief in your product, along with a willingness to fight for your product on every level." - Andrea Pfeifer, Co-Founder and CEO of AC Immune
Glycobiology in the clinic Glycans decorate every cell in the body. As well as most proteins and most recently found on RNA. Advances in glycoproteomics/chemical biology has led to several drug candidates in the clinic targeting glycosylation.
Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression led by James Zengel @JamesZengel from the Jan Carette @CaretteLab lab
Expansion Therapeutics @expansionrx: - Founded in 2016 to develop small molecules targeting RNA - ID'ing druggable RNA structures - Building a pipeline to treat myotonic dystrophy type 1 (targeting splicing), ALS & FTD (translation), and tauopathies
"By asking a novel question that you don't know the answer to, you discover whether you can formulate a way of finding the answer, and you stretch your own mind, and very often you learn something new." - Walter Gilbert, Nobel Prize winner for inventing DNA sequencing