Excited to share our latest in @CellBiomat@CellPressNews! We present a generative AI approach that designs novel antibiotics from scratch.
Using diffusion models guided by a protein LM (ESM-2), we sample novel, grammar-consistent sequences and triage them with our APEX AI…
A lung from a genetically modified pig has been transplanted into a person for the first time. Lungs are complex organs to transplant, but the surgery is a step towards clinical trials.
go.nature.com/3V6sbiZ
RFdiffusion2 now available! Atomic-level scaffolding for complex active sites
Available on @tamarindbio now.
RFdiffusion2 shows state-of-the-art atomic-level scaffolding that generalizes to complex, multi-island active sites, and it reliably yields active enzymes with modest…
One of the first synthetic gene circuits was called the REPRESSILATOR.
It was made from 3 genes, and it "programmed" cells to blink in flashes of green. It also helped kickstart the field of synthetic biology.
But where did the idea to make the repressilator even come from?…
A new paper, in Nature Chemistry, proves that there are still tons of "basic" things to discover in biology. There is so much room at the bottom.
TL;DR: Researchers discovered a new type of post-translational modification, called “oligophosphorylation.” Rather than being tagged…
I had no idea that humans lost our natural defense against HIV to fight an even worse retrovirus that no longer exists
Old world monkeys still have this immunity - we share the same gene (Trim5-α) - but ours was repurposed millions of years ago
Ep w @jacobkimmel out tomorrow
Our paper on autonomous scientific research is accepted to Findings of #EMNLP2025! 🎉
We introduce Agent Laboratory, a framework that accelerates scientific discovery by teaming human researchers with LLM agents.
A few years later, two of the greatest organic chemists in the world: Woodward from @Harvard and Eschenmoser from @ETH_en achieved what is often regarded as the “Everest of organic synthesis”:-the total synthesis of Vitamin B₁₂. A 12 year effort with nearly 100 postdocs.
A few years later, two of the greatest organic chemists in the world: Woodward from @Harvard and Eschenmoser from @ETH_en achieved what is often regarded as the “Everest of organic synthesis”:-the total synthesis of Vitamin B₁₂. A 12 year effort with nearly 100 postdocs. https://t.co/mSRE5P4NdU
@KarolinaZioloP@donaldtusk@NCN_PL Pani Minister, czy dobrze rozumiem, ze 8 miesięcy trwały między resortami nauki i finansow ustalenia, że można obligacje wykorzystać bez ustawy? Czy ncn dostał decyzje na piśmie?
A recent survey of nearly 900 postdocs at the Max Planck Society reveals:
🔹 28% show signs of severe depression
🔹 25% struggle with severe anxiety
🔹 More than half oppose contract caps that force them out after 4–6 years
🔹 International researchers (75% of the cohort) face…
Longevity gene therapy paper retracted. First retraction for George Church. Situation involved BioViva, co. headed by unlikely longevity figure Liz Parrish.
Best quote from co-author: “I have retired and I am in Greenland. I do not have to talk to you.”
retractionwatch.com/2025/08/13/geo…
@ladanuzhna IMO the reason people don't work on this is they aren't aware that terraforming Mars would take a couple decades and cost as much as the interstate highway system. A big deal, but not 'romans making LLMs'
Somebody's gotta see it first @Pioneer__Labserikadebenedictis.com/s/The-case-for…
Two recent papers used deep learning to either create, or discover, new antibiotics.
I'll first look at the paper that made new antibiotics from scratch (and then maybe write another post about the discovery paper.) The crazy thing about this paper, in particular, is that they…
Death to PDFs. Would love to see something like a knowledge graph where each paper has figures that are connected to analysis scripts and raw data, as well as the claims being made and how they tie in to other figures in the paper, references, etc. Each node (whether it be claim,…
Death to PDFs. Would love to see something like a knowledge graph where each paper has figures that are connected to analysis scripts and raw data, as well as the claims being made and how they tie in to other figures in the paper, references, etc. Each node (whether it be claim,…
From 1927-1947, Harvard operated a "Fatigue Laboratory." A lot of their research was never published. But we know they were involved in:
1. Lots of self-experiments.
2. Development of early methods to study molecules in blood.
3. Refining meals given to soldiers during WWII.…
Protein designers have long dreamed of building new enzymes from scratch.
Unfortunately, enzymes are highly dynamic; they move around a lot and have intermediate states that are difficult to design computationally.
But a recent paper from David Baker’s group at the Institute…
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1K Followers 908 FollowingMax Planck Research Group Leader
tRNAslational Control of eukaryotic Gene Expression
Structural Biology #tRNA #Elongator #Urm1 #RNA
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Od nauk ścisłych po humanistykę.
Wysoki poziom publikowanych tekstów.
#eksperymentmyslowy
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336 Followers 440 FollowingChemist :) Assistant Professor at @czt_uam in Poznań. Head of the @fhratzLab. Organic and coordination mechanochemistry🧪Popularization of science🤓
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Views my own.
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152 Followers 365 FollowingWe are a global leader in the innovative design and manufacture of highly-customized controlled environment chambers. #HelpingYouCreateBetterScience
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Wiele lat w @Radio_TOK_FM Mama cudnego synka.
4K Followers 900 FollowingNews and discussion for EMBO Young Investigators and Installation Grantees. Expect tweets about EMBO activities, publications, awards, collaborations etc.
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