Matteo Parri @MatteoParri2
Microscopist, cell biologist and former research @uni_firenze. Microscopy applications and support @NikonInst, love for classical music. Firenze, Italy Joined December 2019-
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🔴 Meet silicon-rhodamine-enabled identification #SeeID, a method for #NIR light-mediated proximity labeling using silicon rhodamine as both a photocatalyst and fluorophore, demonstrated at an ~2 mm labeling depth in a mouse brain. 🔗 View the article: nature.com/articles/s4146…
🔬 What can the @CrestOptics X-Light V3 #SpinningDisk #Confocal or DeepSIM #SuperResolution #SIM system do for your imaging? 🧠 This image compares widefield, the X-Light V3, and DeepSIM for imaging of a mouse hippocampal coronal section. 🔗 Learn more: bit.ly/45G8Ueh
📄🔬 Preprint research introduces a combination of #SuperResolution single molecule localization #Microscopy #SMLM and expansion microscopy #ExM (7-8X expansion) able to resolve the 8 nm periodicity between alpha/beta-tubulin heterodimers in microtubules: bit.ly/3HJm0Ot
🔬🧘 The ECLIPSE Ti2-I motorized inverted #Microscope helps keep your #IMSI/#ICSI workflow simple. ✨ Push a button to switch between key observation mode settings for the #IVF lab, including optimal illumination brightness. 🔗 More about the Ti2-I: bit.ly/4ojf1w9
⚡ Supercharge your #Microscopy with our #SuperResolution #NSPARC detector and Enhance_ai software module 🔗 This #AppNote shows how Enhance_ai can provide nearly the same image quality from a 2D NSPARC image as from an image in a 3D deconvolved Z-stack: bit.ly/3J0Y3mk
📄 In a recent #Microscopy #AppNote, we validate the @AIMBiotech idenTx series of #OrganOnChip plates for a 3D #Angiogenesis assay of drug efficacy. 🔬 High-res 3D imaging was performed using the Nikon AX #Confocal #Microscope system. 🔗 Learn more: bit.ly/3TT2QZa
🤔 What’s it like using Nikon’s #DeepLearning-based NIS_ai modules for the NIS-Elements #Microscopy software? 📹 In this video, we outline the use of our Segment_ai module for segmentation of image features. 🔗 Learn more: bit.ly/4nZjDri #AI #Microscope #Imaging
⏱️ 🔬 How much time can the ECLIPSE Ti2-I motorized inverted #Microscope for #ICSI and #IMSI save your workflow? 📹 In this video, the same ICSI workflow was completed ~44% faster using the Ti2-I compared to a manual microscope. 🔗 Learn more: bit.ly/4kBJxhJ
🖼️ Image from @MoffittNews shows a patient-derived xenograft ovarian cancer model. 🔬 Imaging was performed using a Nikon AX R #Confocal #Microscope system. Cell nuclei are in blue, epithelial cells in green (EpCAM), infiltrating T cells in red (CD4), and actin in magenta.
🔬 #FeedbackMicroscopy with NIS-Elements bridges the milli- and micrometer scales. 🔗 In this #Microscopy #AppNote, we describe a pipeline for automated whole juvenile medaka fish imaging, identification of neuromasts, and high-res follow-up imaging: bit.ly/3SQDg6z
🧬 Understanding how drugs work at the molecular level is important for #DrugDevelopment. #smFISH is used to quantify how drugs impact mRNA expression. 🔗 Our #NikonBioImagingLabUSA team has extensive smFISH experience and are ready to assist you: bit.ly/3FTbaVe
👀 ICYMI, we’ve released plan-corrected versions of our well known 20X and 40X long working distance water immersion objectives with superior image flatness. 🔗About the new CFI Plan Apochromat LWD Lambda S Series 20XC and 40XC water immersion objectives: bit.ly/45Eo6Zt
📄🔬 New preprint details the combination of #SuperResolution single molecule localization #Microscopy #SMLM with shock freezing and observation using a microscope housed in a liquid-helium cryostat to realize sub-nanometer localization precision: bit.ly/4kBQFLl
🐟🔬 Preprint research from the lab of Dr. Brant Weinstein at the NICHD details a #TissueClearing method using the water-based LUCID clearing reagent for cellular-resolution 3D imaging of whole larval and juvenile #Zebrafish. 🔗 View the preprint here: bit.ly/4k6VSv3
📣 #AACR2025 begins tomorrow, April 25th! Find us at booth 3606 to learn about out our #Microscopy solutions for #CancerResearch. 🔗 More information: bit.ly/3S0jYeh 🧑🔬 You can also book a micro-consultation with the #NikonBioImagingLabUSA: bit.ly/4lzZWoD
🎉 Announcing the 100th anniversary of our original JOICO #Microscope 🎉 🔬 As we mark 100 years of #NikonMicroscopy, we reaffirm our strategic vision as described by our key message: “Accelerating life science with the power of light.” 🔗 More info: bit.ly/4l8NJae
🔬 Our recent #Microscopy #AppNote compares the performance of our GA3 software package for NIS-Elements with other commercial and open-access software options for nucleus and cell segmentation and quantification using pseudoislet #Organoid images: bit.ly/43wD2be
We're thrilled to announce that our historic Nikon microscopes will be on display at ARTIS | Natura Artis Magistra - #Micropia in Amsterdam, NL 🔬✨ Included at the exhibit is the JOICO, our very first microscope introduced in 1925! Learn more 👉 bit.ly/4hECG5I
New #AppNote explores how the Nikon AX / AX R #Confocal system with @PicoQuant LSM Upgrade Kit combines the power of #FLIM with data-driven “feedback #Microscopy” using the NIS-Elements software – where real-time analysis results guide the experiment: bit.ly/41vxs6n
A perspective in @CellRepMethods compares #Imaging methods for whole-brain mammalian #Connectomics, focusing on the potential of developing a high-throughput pipeline combining #SuperResolution expansion #Microscopy #ExM and #LightSheet: bit.ly/3XDjE8C #Neuroscience

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