Vik Dhillon @OpsBug
Physician, author, ML enthusiast. Interested in biology of aging. Tweets = own. 📸: George Dunbar Detroit, MI Joined August 2013-
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Vik Dhillon retweeted
New online! Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia nature.com/articles/s4157…
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Vik Dhillon retweeted
“garbage in, garbage out”: last week, Nature Methods published an article (nature.com/articles/s4159…) comparing the deep learning models trained on scRNA-seq (single-cell transcriptomes) which were published in recent years — GENEFORMER, scGPT, scBERT, scFoundation, and others.
Vik Dhillon retweeted
#IntheSpotlight A FABulous Couple: Adding PHENotype to GENotype Improves HMA/VEN Response Prediction in AML brnw.ch/21wUNVw
Vik Dhillon retweeted
Everyone working in a STEM field should read this - ‘writing is thinking’ nature.com/articles/s4422…
Vik Dhillon retweeted
We are excited to share our work on "closing the loop" 🔄 - a framework enabling single-cell foundation models (scFMs) to learn from experimental validation and dramatically improve their predictive accuracy! (1/n)
Vik Dhillon retweeted
Excellent example of the core issue I was trying to get at wrt "virtual cells" - optimizing a prediction objective will not necessarily provide an accurate representation of physical or biological phenomena. It's extremely important to be very clear about this. 1/
Excellent example of the core issue I was trying to get at wrt "virtual cells" - optimizing a prediction objective will not necessarily provide an accurate representation of physical or biological phenomena. It's extremely important to be very clear about this. 1/
Vik Dhillon retweeted
Clu+ HSCs represent myeloid/platelet-biased HSCs that expand with age, whereas Clu– youthful HSCs become underrepresented with age. ow.ly/cyJP50WkB7y #hematopoiesisandstemcells
Vik Dhillon retweeted
🚨New paper on theories of ageing I discuss the major mechanistic theories of ageing in light of recent findings as well as the fundamental nature of the ageing process. Theoretical work is more important than ever in biology, including in ageing. nature.com/articles/s4155…
Vik Dhillon retweeted
New research shows that heat application, not cold, enhances recovery from muscle damage physoc.onlinelibrary.wiley.com/doi/full/10.11…
Vik Dhillon retweeted
Still digesting all the data from #ASCO25. Wanted to share my thoughts on a topic I found particularly fascinating: the timing of checkpoint inhibitor infusions. I'm no expert in chronobiology, but the data presented seem compelling and sparks a lot of questions.
Vik Dhillon retweeted
Vik Dhillon retweeted
Over the last 2 weeks, I took a deep dive into Evo 2, Arc's Genomic Foundation model. But, I couldn't find a crisp primer on Evo 2 that covered the decisions for the ML architecture, the inference-time scaling results or the mechanistic interpretability results. So, I wrote one!
Over the last 2 weeks, I took a deep dive into Evo 2, Arc's Genomic Foundation model. But, I couldn't find a crisp primer on Evo 2 that covered the decisions for the ML architecture, the inference-time scaling results or the mechanistic interpretability results. So, I wrote one!
Vik Dhillon retweeted
There are traditionally two types of research: problem-driven research and method-driven research. As we’ve seen with large language models and now AlphaEvolve, it should be very clear now that total method-driven research is a huge opportunity. Problem-driven research is nice…
Vik Dhillon retweeted
Delighted to share our study out in @CellStemCell today from the dream team @PapaemmanuilLab @iannisaifantis1 @AkEisfeld @landau_lab! We profiled IDH-mutated AML patients to define how IDH and co-mutations shape the disease at baseline and responses to IDH-inhibitors. 🧵👇
Vik Dhillon retweeted
Adult Acute Lymphoblastic Leukemia: 2025 Update on Diagnosis, Therapy, and Monitoring |American Journal of Hematology | Blood Research Journal | Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10…
Vik Dhillon retweeted
A number of people have asked me why we titled our recent paper "On the Biology of a Large Language Model". Why call it "biology"?
Vik Dhillon retweeted
Vik Dhillon retweeted
Just out: My 2024 Update on diagnosis, risk stratification, and treatment of myeloma. #AJH @MayoCancerCare 10 Tables; Algorithms Includes current data including trials published this month! #ASCO24 onlinelibrary.wiley.com/doi/10.1002/aj…
Vik Dhillon retweeted
What protects individuals from developing blood cancers? Thrilled to share my work in @bloodgenes lab, describing inherited resilience protecting blood stem cells from clonal hematopoiesis by modifying RNA regulation. 🧵👇(1/n) biorxiv.org/content/10.110…
Vik Dhillon retweeted
🚩mini #tweetorial on Ph like ALL 1⃣/8⃣ ⚡️“Ph-like”or BCR-ABL1-like ALL was described by the COG& Dutch COG by GEP in 2009 ⚡️Adopted in 2016 update of WHO as provisional entity ⚡️lacks the BCR-ABL1 translocation but similar gene expression as Ph+B ALL #medtwitter #hemonc #leusm
WSU/DMC Internal Medi... @wsuim
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Sushmitha Nanja Reddy @NanjaSushmitha
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Suresh Balasubramania... @malignantheme
346 Followers 157 Following Translational hematologist interested in myeloid neoplasms/CHIP. Dual faculty at Karmanos and CCF. Tweets are mine and don’t reflect the views of my employer!
Abdul Moiz Khan @abdulmoiz92
887 Followers 2K Following Hematologist/Oncologist at SwedishAmerican Hospital UW Health | Former Chief Fellow @karmanoscancer @waynestate | IM @AlbanyMed | @kemuofficial alumnus |
Richa Parikh @richaparikh36
637 Followers 469 Following Multiple myeloma and BMT specialist @WinshipAtEmory | Alumni @karmanoscancer @UAMSMyeloma @UAMSintmedicine | Lifestyle factors in plasma cell disorders
Joel M. Topf, MD FACP @kidney_boy
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Cambridge Society of ... @culongevity
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Anisha Rajavel @AnishaRajavel
17 Followers 86 Following Hematology/Oncology Fellow 🧬 Karmanos Cancer Institute
Sankalp Arora, MD @sankalparoraMD
957 Followers 391 Following Heme/Onc fellow @MDAndersonNews | Alum @uabimres and Seth GSMC/KEMH | Interests include Heme malignancies, BMT/Cellular therapy | @ASCOTECAG |
Kim Aldecoa, MD @kim_aldecoa
192 Followers 381 Following Hem/Onc fellow at @UCIrvineHealth | Former IM Chief @THO_WSU_IM @waynemedicine | Passion for Teaching | RMT, MD 🇵🇭
Fernanda Gutierrez-Ro... @fergutierrezro1
201 Followers 179 Following Research Fellow at NHLBI 🩸🧬| Focused on genomics, hematopoiesis, BMFs and autoimmunity | #SAA #IBMFS #CHIP #BMF #VEXAS #genomics
Dear Son. @DearS_o_n
1.3M Followers 406 Following A dad to 5 sons. I give actionable advice to young men on how to live their full potential. My full guide coming out soon!
Ian Maurer 🧬 @imaurer
1K Followers 1K Following CTO @GenomOncology #genomics #precisiononcology #nlp
Lucas Camillo @lucascamillomd
547 Followers 48 Following Medical Student @Cambridge_Uni • ML Advisory Lead @ShiftBioscience • Fellow @FundacaoEstudar
Khaled Saab @_khaledsaab
3K Followers 388 Following Researcher @OpenAI, prev: RS @GoogleDeepMind PhD @StanfordAILab @HazyResearch
Bartomeu Colom @Bartomeu_Colom
2K Followers 756 Following Senior scientist @altos_labs, previously @sangerinstitute. Stem cells, somatic mutations & cell competition in aging and early cancer. Views are my own.
Georgio Medawar, MD @GeorgioMedawar
451 Followers 508 Following Hem/Onc fellow @MUSChealth @muschollings | IM @RWMCIM | Interests in Leukemia, BMT, Cellular Therapies | 🇱🇧 🇺🇸
Chris Mason @mason_lab
12K Followers 940 Following Professor of Genomics, Physiology, & Biophysics @WeillCornell Medicine. Co-Founder / COI @BiotiaNYC, @UrsaBio & @Onegevity (@thornehealth)
Paolo Gallipoli @PaoloGallipoli
915 Followers 323 Following Clinical academic haematologist CRUK ACSF @CR_UK. Barts Cancer Institute @qmbci Interest in myeloid leukemia biology and therapy. Tweets are mine
Ghayas Issa @GhayasIssa
774 Followers 299 Following Leukemia Physician at MD Anderson. Research in AML, CML, other leukemias if it's the right genotype. Views expressed here are my own.Trends for United States
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