Simone Fouché @SimoneFouche
NGS and genomic dark matter 💜💜💜 Cape Town, South Africa Joined June 2011-
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Simone Fouché retweeted
945 Han Chinese @nanopore sequenced & analyzed! Identified SV with functional impact (e.g WWP2 & GSDMD) & validated them on mouse models + HELA ! Spoiler non coding SV impact enhancers :) Amazing collaboration with Shaohua Fan @FudanUni Link: medrxiv.org/content/10.110… @BCM_HGSC
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Simone Fouché retweeted
Omics! Omics! First Illumina Complete Long Reads Preprint omicsomics.blogspot.com/2024/05/first-…
Simone Fouché retweeted
Tandem repeat @GenomeInABottle benchmark @NatureBiotech out today: rdcu.be/dFQNN . Characterization of 1.7 million TR + benchmark variants + new method to overcome var. representation issues! Great work lead by Adam E. @BCM_HGSC & great collab. from so many! (1/4)
Simone Fouché retweeted
Human telomere length is chromosome end–specific and conserved across individuals | Science science.org/doi/10.1126/sc…
Simone Fouché retweeted
Imprinted genes and the manipulation of parenting in mammals go.nature.com/46gtLlO #Review by Rosalind M. John @preg_lab, @mj_higgs & @ProfAntIsles @cardiffuni @neurosciencecu
Simone Fouché retweeted
If you’re interested in rapid in-situ metagenomics with Oxford @nanopore MinION, here’s a great example of how a lab-in-a-suitcase approach can achieve same-day on-site results, allowing “real-time functional and taxonomic monitoring of microbial communities in remote areas”.…
Simone Fouché retweeted
☃️David's paper about mutational coldspots in the human genome is now out in @NAR_Open! Read the latest and greatest version here: academic.oup.com/nar/advance-ar…
☃️David's paper about mutational coldspots in the human genome is now out in @NAR_Open! Read the latest and greatest version here: academic.oup.com/nar/advance-ar… https://t.co/VpQICP0RhE
Simone Fouché retweeted
Considering building a human pangenome? Dive into our latest preprint for insights on the sequencing technologies and the minimal coverages needed for accurate assemblies biorxiv.org/content/10.110… Joint work with Prof JJ Liu lab w/@msprasad693, @JosipaLipovac and Filip Tomas!!
Simone Fouché retweeted
Gapless assembly of complete human and plant chromosomes using only nanopore sequencing | bioRxivc Happy @keygene could contribute to this work. @nanopore #T2T #duolex biorxiv.org/content/10.110…
Simone Fouché retweeted
Pls RT We have a #postdoc fellowship within the #GenomicsForHealthInAfrica #AfricaEuropeCoRE Come and make an impact on the millions of Africans living with #RareDiseases and #Cancer The @RareGenomicsRSA team is amazing, as are all our collaborators in the MAGIC lab in the #BMRI
Pls RT We have a #postdoc fellowship within the #GenomicsForHealthInAfrica #AfricaEuropeCoRE Come and make an impact on the millions of Africans living with #RareDiseases and #Cancer The @RareGenomicsRSA team is amazing, as are all our collaborators in the MAGIC lab in the #BMRI
Simone Fouché retweeted
Interested in chromosome number or centromere structure evolution? Giant chromosomes and mini-chromosomes? Pathogenicity-specific horizontal gene transfer? Find all these and more in this massive piece of work led by @MarcoACoelho1 and @MrciaDavidPalm1. biorxiv.org/content/10.110…
Simone Fouché retweeted
New in @ScienceMagazine with @jaegc. A combinatorially complete fitness landscape with >260.000 E.coli genotypes shows unexpected 🤯 properties. Despite ~500 fitness peaks in this landscape, adaptive evolution can easily navigate to highest fitness peaks science.org/doi/10.1126/sc…
Simone Fouché retweeted
📢CALLING ALL MICROBIOLOGISTS📢 Do you use CFU assays? Here is a new high-throughput, low-waste viability assay for microbes All you need is agar media, pipette tips and a standard camera 🧫📸 nature.com/articles/s4156… @meyerct6 @danastamo
Simone Fouché retweeted
Another book review dropped! Are mutations random? | Evolution | Oxford Academic academic.oup.com/evolut/article…
Simone Fouché retweeted
Mobile element insertions in rare diseases: a comparative benchmark and reanalysis of 60,000 exome samples. #MobileElements #RareDiseases #Benchmarking @ejhg_journal nature.com/articles/s4143…
Simone Fouché retweeted
Happy to see this paper out! With @AmLarracuente, we review the implications of intragenomic conflicts mediating the co-amplification of gene families on sex chromosomes, and how this process might be fueled by sex-biased mutation. royalsocietypublishing.org/doi/10.1098/rs…
Simone Fouché retweeted
Another paper in our @RSocPublishing special issue on the resolution of evolutionary conflicts: ‘Genetic conflict and the origin of multigene families: implications for sex chromosome evolution’ Great work from @emilianomarti7 + @AmLarracuente! royalsocietypublishing.org/doi/10.1098/rs…
Simone Fouché retweeted
I always assumed that the P-element was the latest invader in D.mel. -> I was wrong, there is Spoink; many thanks to @signor_molevol @r_pianezza @Almoro_Scarpa for super fun collaboration :) biorxiv.org/content/10.110…
Simone Fouché retweeted
Our latest work now in @Nature. Check out what else we're doing at TheDarkMatterProject.org
Our latest work now in @Nature. Check out what else we're doing at TheDarkMatterProject.org
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Bioinformatics at UM6... @BioinfoAtUM6P
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antisense. @razoralign
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443 Followers 316 Following Group Leader—Developmental Molecular Genetics Lab and NHMRC Emerging Leadership Fellow at Mater Research Institute-UQ. Mama of 2. She/her. Views my own.
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658 Followers 623 Following Moved to @marcofumasoni.bsky.social. Leaving the profile up for a little longer before closing it for good.
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1K Followers 744 Following Wheat genetics, evolution, genome biology and plant-pathogen interaction
Sridhar Bhavani -Whea... @SridharBhavani
350 Followers 197 Following Principal Scientist, Wheat improvement lead for East Africa, Head of rust reseach CIMMYT. Expertise in wheat breeing, rust pathology genetics, https://t.co/zeMOKIHraa, NARES
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309 Followers 120 Following
Thomas Walle @science_wallet
753 Followers 951 Following trying to help patients by understanding their individual immune status 🇪🇺 https://t.co/fvbzNRmYGZ…
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517 Followers 569 Following Interests: Bioinformatics, SVs, SNVs, comparative genomics, data science.
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155 Followers 192 Following Experimental Population Geneticist, Evolution of Genetic Systems, Science Twitter Account
Katalin Kariko @kkariko
66K Followers 231 Following I am a scientist, working on the therapeutic use of in vitro transcribed mRNA.
Alice Laigle (moved t... @AliceLaigle
237 Followers 486 Following PhD student in @danielcroll's team 🇨🇭. Chromatin & Evolution 🍄-🌾. Hobbies: 🧗🏼♀️🎨⛵🌍 🇲🇫 (She/her) 🦋 @alicelaigle.bsky.social
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2K Followers 342 Following UOttawa Professor - University Research Chair - If you know the enemy and know yourself, you need not fear the result of a hundred battles
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4K Followers 3K Following Prof @ASU, host/producer @ZombifiedMedia & author. Figuring out how to thrive in the apocalypse! Ask me about my alternative book tour: @apocaroadshow
Toby Kiers @KiersToby
5K Followers 501 Following Executive Director SPUN Professor of Evolutionary Biology (VU, Amsterdam) Evolution of Cooperation, Symbiosis, Fungi https://t.co/lBs7l7gpZ2 / https://t.co/0OMWTOYtY3 (she/her)
Cejka Lab @CejkaLab
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