Stephen Sykes @TheSykesLab
Sykes Lab focused on the study of healthy and malignant hematopoiesis. thesykeslab.com Missouri, USA Joined May 2019-
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Stephen Sykes retweeted
How it started (undergrad who thinks grant writing is fun🤓) vs how it’s going (A PAPER IN BLOOD🩸!) excited to share the FULL ATF6 story with the world! Thank you to my amazing co-authors and mentor @TheElfLab for helping my six year long dream come true! ashpublications.org/blood/article/…
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Stephen Sykes retweeted
Read our latest #research on #extramedullaryAML published with @SpringerNature in @BloodCancerJnl Thanks to the @LeukemiaRF for funding this work! ⬇️⬇️⬇️ rdcu.be/eADE4
Stephen Sykes retweeted
I am deeply honored and immensly grateful to the scientific community at ISEH for receiving this award! And a big shoutout and thank you to all the brilliant and hard-working former and current members of my lab who made the progress possible that led to this award! 😊 🙏
I am deeply honored and immensly grateful to the scientific community at ISEH for receiving this award! And a big shoutout and thank you to all the brilliant and hard-working former and current members of my lab who made the progress possible that led to this award! 😊 🙏
Stephen Sykes retweeted
#StandUpForScience2025 @SitemanCenter @WashUOncology @washumedicine DONT’T CUT SCIENCE FUNDING!!!
Stephen Sykes retweeted
Stephen Sykes retweeted
Unsolicited advice to new PIs and my opinion only not fact: As a new Assistant Professor, you have a 1-1.5 year window where you can get an R01 without a corresponding author paper IF you have a high impact 1st author paper from your postdoc. After that, it seems no amount of…
Stephen Sykes retweeted
Stephen Sykes retweeted
Our preprint using EGFL7 to expand HSCs is FINALLY out 🙌🏻 🎉 🩸 biorxiv.org/content/10.110…
Stephen Sykes retweeted
Stephen Sykes retweeted
Delighted to see our CLN1 & CLN2 Enteric Nervous System gene therapy paper published in @ScienceTM today! Big team effort with many great colleagues @HeuckerothLab @WashUMedPeds & directly inspired by Batten families @BDSRA @NIH_NINDS @noahs_hope1 science.org/doi/10.1126/sc…
Stephen Sykes retweeted
Excited to share our latest work published today in @SciImmunology and featured on the cover! This study demonstrates that thrombospondin-1 (Thbs1) is a driver of hematopoietic aging and that targeting Thbs1 suppresses inflammaging and restores systemic and HSC healthspan.
Excited to share our latest work published today in @SciImmunology and featured on the cover! This study demonstrates that thrombospondin-1 (Thbs1) is a driver of hematopoietic aging and that targeting Thbs1 suppresses inflammaging and restores systemic and HSC healthspan.
Stephen Sykes retweeted
@c_constan Entirely the wrong spin. A positive spin is that LLMs can be used to integrate interrelated findings to develop research questions to be tested. Until the experiment is run it is foolish to assume we know the outcome no matter who is doing the predicting.
Stephen Sykes retweeted
Very fun and productive collaboration with Bobby Bowman & @rosslevinemd modeling mutation order and oncogenic dependency in AML. I've always wanted to do this but we were previously limited by available tools... this is a huge step forward! authors.elsevier.com/c/1k4rd5TA51hP…
Stephen Sykes retweeted
My very talented graduate student @nsarellano9 wrote a highlight in @eLife on beautiful work by first author Rebecca Warfvinge that links cellular heterogeneity in CML stem cells to TKI response. Check both out below! elifesciences.org/articles/92074 elifesciences.org/articles/103775
Stephen Sykes retweeted
T-48 hrs until the start of our 3rd Annual @WashUHeme Retreat! Excited to hear about the latest research from our trainees & faculty, and especially thrilled to welcome @aswolberg for the Evan Sadler Special Lectureship! #hematology @WashUDeptMed
Stephen Sykes retweeted
Here's the workshop I really want to attend: "how to use ChatGPT to fill out mindless university bureaucratic paperwork"
Stephen Sykes retweeted
BM Fibroblasts -say what 👀 Our paper is finally out!! Using our unique model of AML with long latency to investigate changes in BMM before disease onset: rdcu.be/dVNvj 🩸 🧬 🧪 #AML #Leukemia #Fibroblasts #microevironment
Stephen Sykes retweeted
You truly won’t believe your eyes when you come to Sundance for #WBC25!!!!
Stephen Sykes retweeted
This week selection of papers in myeloid leukemia biology and therapy is out! In a shameless self-promotion the pick of the week is our group paper on SCD inhibition in AML! Enjoy it biomed.news/bims-tremyl/20… Thanks as always @Bims_BiomedNews Below the pick nature.com/articles/s4137…
Stephen Sykes retweeted
I am very excited to share that our manuscript from @Ferraro_lab @washumedicine is out in @CCR_AACR . We show through several orthogonal methods the changes that mutant Myc orchestrates in the hematopoietic compartment resulting in AML. aacrjournals.org/clincancerres/…
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