alex math @alexmathalex
ml meets proteins Cambridge, England Joined April 2022-
Tweets679
-
Followers98
-
Following126
-
Likes1K
Biology’s lack of data is holding back its AI boom. Epoch’s latest report shows explosive growth in biological model training data size from 2017–2021 (9.7×/year), but a (2.1x/year) plateau since. AI models for biology are ready to transform science if the data can keep up.
(1/n) Sampling from the Boltzmann density better than Molecular Dynamics (MD)? It is possible with PITA 🫓 Progressive Inference Time Annealing! A spotlight @genbio_workshop of @icmlconf 2025! PITA learns from "hot," easy-to-explore molecular states 🔥 and then cleverly "cools"…
🚀 After two+ years of intense research, we’re thrilled to introduce Skala — a scalable deep learning density functional that hits chemical accuracy on atomization energies and matches hybrid-level accuracy on main group chemistry — all at the cost of semi-local DFT. ⚛️🔥🧪🧬
Researchers can analyze vast protein datasets faster with MMseqs2-GPU in the MSA-Search NIM. Unlock new possibilities for disease research and therapeutic breakthroughs. #drugdiscovery ➡️ nvda.ws/4kMUoqd
Another great example of the UK's ability to develop unique data to push forward AI for bio infrastructure Props to @Basecamp_Res for launching the world's largest biodiscovery dataset, over 10x the number of protein sequences than are currently publicly available 🧬🚀
Protein structure ≠ protein folding/dynamics The new north star: energy‑landscape learning, rather than static structure prediction Next wave: AI that learns free energy for "true" inverse folding
most underrated fundraising strategy: revenue
🧬 News alert: We’re bringing BaseData out of stealth — the world’s largest and fastest growing biodiscovery dataset, built in collaboration with scientists across 26 countries. 🔍 BaseData adds 9.8 billion newly discovered protein sequences to the known tree of life — expanding…
Exciting work by @Basecamp_Res! Great to see the emphasis on diversity and also the comparison with @tatta_bio's Open MetaGenome (OMG) dataset curated from public databases. I'm super curious - how was the team able to 10x the recovered sequence diversity in the past few months?
Exciting work by @Basecamp_Res! Great to see the emphasis on diversity and also the comparison with @tatta_bio's Open MetaGenome (OMG) dataset curated from public databases. I'm super curious - how was the team able to 10x the recovered sequence diversity in the past few months? https://t.co/D16KgobZbJ
Hot takes, pseudocode, score matching, EBMs and staircases found inside: markneumann.xyz/blog/modeling-…
If you cite Muon, I think you should definitely cite SSD (proceedings.mlr.press/v38/carlson15.…) by @CevherLIONS et al. (sorry I can't find the handle of other authors) -- which proposed spectral descent.
🚨Excited to announce that the Sovereign AI Unit is investing £8m in OpenBind: building the world's largest protein-ligand dataset. Backed by a top UK consortium, inc. Isomorphic Labs and Nobel Laureate David Baker, this will help the UK become the home for AI drug design 1/6🧵
Really pleased to share what I have been working on for 2 months: 🇬🇧 UK SovAI are today announcing our £8m seed investment into OpenBind - A consortium that will actually make AI for drug discovery great by generating 500k experiment protein-ligand complexes!! Explainer 🧵 (1/n)
Really pleased to share what I have been working on for 2 months: 🇬🇧 UK SovAI are today announcing our £8m seed investment into OpenBind - A consortium that will actually make AI for drug discovery great by generating 500k experiment protein-ligand complexes!! Explainer 🧵 (1/n)
🚀 Excited to release BoltzDesign1! ✨ Now with LogMD-based trajectory visualization. 🔗 Demo: rcsb.ai/ff9c2b1ee8 Feedback & collabs welcome! 🙌 🔗: GitHub: github.com/yehlincho/Bolt… 🔗: Colab: colab.research.google.com/github/yehlinc… @sokrypton @MartinPacesa
AGI timelines are very bimodal. It's either by 2030 or bust. AI progress over the last decade has been driven by scaling training compute of frontier systems (3.55x a year, 160x over 4 years). This simply cannot continue beyond this decade, whether you look at chips, power,…
There's an obvious way to fix CVD: removing plaques. There are 2-3 companies doing this. Why so few, given how pervasive CVD is? Lowering LDL is nice but removing plaques periodically seems even better.
i miss gemini-2.5-pro-exp-03-25 so bad :(
The premier conference on Machine Learning for Computational Biology is Sep 9-10 at the NY Genome Center in NYC! Submission deadline is June 1 for 2-page abstracts and 8-page papers (eligible for proceedings track). Registration is now open! (Link below) Please retweet!
We’re now programming energy landscapes, not static folds. Conformational Biasing scans every point mutant 🧬against multiple states in ⏱️<60s on a single 4090—pushing K-Ras ON, tightening Spike-ACE2, rewiring LplA🔧

Jonathan Rayner @JonathanJRayner
123 Followers 1K Following Picking flowers on Earth https://t.co/EKv6gBhIwu
Art @art_555555
33 Followers 308 Following
Kristian Frandsen �... @KrFrandsen
967 Followers 4K Following Researcher @DTUbioengineer Enzyme Discovery | Guest researcher @cpsc_ucph @KU_PLEN | former @HOPE_NNF and #INRAE @BBF_lab | #CAZymes #cryoEM #Engineering #AI
Surag Nair @suragnair
961 Followers 618 Following Machine learning and genetics @Genentech. Previously CS PhD @Stanford.
Nathan Miller @nathanmllr
461 Followers 2K Following Senior Drug Discovery Scientist @DEShawResearch, PhD @mit_hst ‘22, @harveymudd ‘17
Mark Neumann @MarkNeumannnn
3K Followers 1K Following Head of ML at Orbital Materials. BC: Research/Eng at @allenai_org
JM001 @5aaaaaabii
121 Followers 2K Following
Kev Brown @KevBrownGB
2K Followers 2K Following CEO of FanCircles superfan solutions for music artists, influencers and more. Check out our superfan app solutions and FanCircles Notification Passes
Esben Kran @EsbenKC
851 Followers 1K Following I build systems for revolutionaries. @seldonai, @apartresearch, Juniper, ENAIS, AISA.
Fadteam @Fadhli_Latief
131 Followers 3K Following #FadTeam Salamaki Tapada Salama #SircularLivestock #PeternakanSirkular
Martin Mayta @MartinMayta2
214 Followers 573 Following BSc Biotechnology - PhD in Biological Sciences. Teaching assistant professor at @UNRoficial & @UAPArgentina (Argentina)🇦🇷.
Abdul qaim ansar @abdulqaim_ansar
8 Followers 302 Following Undergraduate researcher, Synthetic biologist by profession, Learner by soul.
Ashton C Trotman-Gran... @ATrotmanGrant
3K Followers 2K Following Creative Discovery @ Karyo Studios. Prev: @FiftyYears, @UofT (PhD Immunology). Co-founder, Notch Tx. Stay curious.
Prashant @DeepBioML
3 Followers 266 Following
Efrueeqeq @Efrueeqeq84761
5 Followers 637 Following
Manjit Rana 🇮🇳�... @MR_ManjitRana
598 Followers 1K Following Receptor topology, functionality & evolvability @BruningLab @UniOfAdelaide| MS Med.Gen. @UofGlasgow| Proj Assoc @AIC_CCMB| BDS (H.P. uni)| Fmr Dental Surgeon
CUI LUN🇫🇷🇨�... @omnicui
444 Followers 3K Following Synthetic biology | CRISPR | Institut Pasteur | Adelaide University | SJTU | Professor in Changzhou University
GAMA Miguel Angel �... @miangoar
2K Followers 1K Following Biologist that navigates in the oceans of diversity through the space-time | MSc in Biochem/Bioinfo @ibt_unam 🇲🇽 | Protein evo, metagenomics & AI/ML/DL
Nikil @bionikil
60 Followers 772 Following Just a guy loving the art of biomolecules https://t.co/rLc0lnTMd6
hadeel hosseny @HossenyHadeel
169 Followers 3K Following
Bebeto @Bebetou60702079
2 Followers 459 Following
Ching-Shin Huang @chingshinhuang
84 Followers 708 Following Structural biologist. Open science supporter. Opinions are my own.
Mayur Shirude @MayurShirude3
49 Followers 327 Following Phd student @ RGCB Trivandrum. Exploring epigenetic regulation of hematopoiesis and leukemogenesis. A traveller, 🇮🇳
MasooTiii @Masoud_Kalantar
5 Followers 430 Following PhD at UNR - student in manipulating proteins to make a better world 😅
Rafeeque Mavoor @rafeequemavoor
4K Followers 625 Following 🎨Scientific Illustrator Helping researchers learn scientific illustration through live workshops. 🎓 Founder @scidartacademy
Earaietvu @Earaietvu8814
28 Followers 377 Following
Yann Vander Meersche @yann_vander
94 Followers 298 Following Computational Structural Biologist - WhiteLab Genomics
Hasmeath @Hasmeath8qf
88 Followers 2K Following
Lucas Chae 🌳 @lucas_chae
4K Followers 826 Following iso audience wow fit 🐶https://t.co/c048Y0A0zv other apps 🎯https://t.co/N5aLfEddMJ ⏱️https://t.co/RwTKGKV6jt ADHD Focus 🔔https://t.co/TiPhR0bCPS ADHD Todo 🏳️🌈
Tesmeposm @TesmeposmbwuAi
109 Followers 5K Following
Luessee @Luessee6Hj
136 Followers 5K Following
Tewcla @TewclawiXD
119 Followers 5K Following
Smisha @Smisha34Ln
98 Followers 4K Following
Edward Francisco Mend... @otalvaro_17
237 Followers 1K Following PhD student @uniGoettingen @mpi_nat @CompBioPhys 🇨🇴🫓🏳️🌈🥑
Madson Aragão @madsondeluna
392 Followers 486 Following PhD Student in Bioinformatics. Interested in Machine Learning, Genetics and Protein Design. All opinions/views are my own. #FirstGen 🧬
High Yield Harry @_highyieldharry
245 Followers 5K Following Levered Finance Memes & Satire. Parodying Finance. Instagram FinMeme Account. Sign up for my Credit and Buyside focused Newsletter⬇️
Sawsueski @SawsueskiG5264
62 Followers 2K Following
Soojung Yang @SoojungYang2
926 Followers 899 Following Molecular simulations and AI for proteins! PhD student @ MIT @RGBLabMIT / website: https://t.co/xHAeCEclfm
David Johnson 🟢 @DavidJohns836tt
53 Followers 784 Following I'm Dave Johnson, Powerball winner of $298.3 million! Giving away $30,000 to every individual who is ready to claim. § Follow me now!
ASI @duskUK
4 Followers 81 Following We're a new deep tech startup, currently in funding negotiations.
Matt Burgess @MattBurgessFSP
16 Followers 125 Following ML Talent Acquisition Lead - Flagship Pioneering @Flagshippioneer is a venture creation engine focusing on building exceptional AI companies
Lucas Chae 🌳 @lucas_chae
4K Followers 826 Following iso audience wow fit 🐶https://t.co/c048Y0A0zv other apps 🎯https://t.co/N5aLfEddMJ ⏱️https://t.co/RwTKGKV6jt ADHD Focus 🔔https://t.co/TiPhR0bCPS ADHD Todo 🏳️🌈
Kyle Tretina, Ph.D. @AllThingsApx
4K Followers 461 Following Follow for AI in Digital Biology and Drug Discovery @NVIDIA, ex Insilico Medicine, ex Yale, PhD UMaryland, views are mine, DM for collabs
Mark Neumann @MarkNeumannnn
3K Followers 1K Following Head of ML at Orbital Materials. BC: Research/Eng at @allenai_org
Rafeeque Mavoor @rafeequemavoor
4K Followers 625 Following 🎨Scientific Illustrator Helping researchers learn scientific illustration through live workshops. 🎓 Founder @scidartacademy
JCIM & JCTC Journals @JCIM_JCTC
10K Followers 976 Following Tweets from Journal of Chemical Information and Modeling (JCIM) and Journal of Chemical Theory and Computation (JCTC) from @ACSPublications
Ruiyu Wang (王瑞雨... @ruiyuwangmd
172 Followers 290 Following Postdoc researcher. @tiwarylab University of Maryland, College Park. PhD, Dr. Eric Borguet (@TUChemBot), Dr. Carnevale (@carnevalelab)
clem 🤗 @ClementDelangue
155K Followers 5K Following Co-founder & CEO @HuggingFace 🤗, the open and collaborative platform for AI builders
Thomas Wolf @Thom_Wolf
94K Followers 6K Following Co-founder at @HuggingFace - open-source and open-science
Olexandr Isayev 🇺�... @olexandr
10K Followers 4K Following #CompChem Prof @CMU_Chem. Connecting chemical sciences with AI & #MachineLearning. #tarheels fan. Care:#design, #photography #Ukraine #cats🐈 Rants are mine
Madson Aragão @madsondeluna
392 Followers 486 Following PhD Student in Bioinformatics. Interested in Machine Learning, Genetics and Protein Design. All opinions/views are my own. #FirstGen 🧬
Retro Biosciences @RetroBio_
7K Followers 3 Following We're Adding 10 Years to Healthy Human Lifespan
Logan Kilpatrick @OfficialLoganK
209K Followers 2K Following Lead product for @GoogleAIStudio + the Gemini API. My views!
Jason Kelly @jrkelly
29K Followers 2K Following Co-founder and CEO at Ginkgo Bioworks ($DNA)🧬 Former Chair of US National Security Commission on Emerging Biotechnology 🇺🇸
José Luis Ricón Fer... @ArtirKel
22K Followers 1K Following Head of Theory at @RetroBio_ , enjoyer of things, blog: https://t.co/8xDYgWAJHB
Marlene Wind @MwiWind
11K Followers 3K Following Prof. European politics and law at @uni_copenhagen 🇪🇺 Special Advisor to HR/VP | @EUI_EU alumni | Columnist at @Berlingske | Personal account
Ben Chamberlain @DrBPChamberlain
2K Followers 793 Following Building foundational models of science @EITOxford https://t.co/qukbizP2Yn 🎓 https://t.co/Ln7xZeV3OA
Lykke Friis @lykkefriis
56K Followers 5K Following Director @thinkeuropa; @ecfr co-chair; board of @teamdanmark Fm. 🇩🇰minister of climate, energy and gender equality #miasanmia🇩🇪
Jennifer Lin @Jlindig0
2K Followers 759 Following Curing rare diseases using science and market dislocation. CEO @ AUG Tx (P3 in ultra-rare). @thielfellowship
The Align Foundation @Align_Bio
2K Followers 284 Following Improving life science with programmable experiments. 🧬 🤖 Home of the Protein Engineering Tournament & Open Datasets Initiative
Simona Cristea @simocristea
9K Followers 497 Following cancer genomics AI scientist; head of Data Science & AI and group leader @DanaFarber_Hale; research scientist @Harvard; phd @eth.🇷🇴🇸🇪🇨🇭🇺🇸
Ali Madani @thisismadani
7K Followers 1K Following Founder & CEO of Profluent (https://t.co/GpoVdKW1zQ, we're hiring!). AI+Biology to cure disease. Berkeley PhD. formerly Research @ Salesforce AI.
Biology+AI Daily @BiologyAIDaily
14K Followers 266 Following Protein/Antibody Designer, AI for drug design, Deep learning and large language model. Share daily papers on biology + AI
Walker Deibel @walkerdeibel
14K Followers 52 Following I help people buy businesses and invest in alternatives / WSJ Bestselling Author #BuyThenBuild / Advisor on $500,000,000+ in acquisitions
Michael Levin @drmichaellevin
63K Followers 3K Following Scientist at Tufts University; my lab studies anatomical and behavioral decision-making at multiple scales of biological, artificial, and hybrid systems.
Seth Bannon @sethbannon
33K Followers 673 Following Entrepreneur, investor. Founder of @fiftyyears. Make something civilization needs. Also: https://t.co/xhMPeOCKIN
Chaitanya K. Joshi @chaitjo
9K Followers 973 Following PhD student @Cambridge_CL. Research Intern @AIatMeta and @PrescientDesign. Interested in Deep Learning for biomolecule design.
Matt Clifford @matthewclifford
33K Followers 2K Following Co-founder @join_ef; Chair @ARIA_Research; UK AI
Kevin K. Yang 楊凱�... @KevinKaichuang
21K Followers 6K Following Principal Researcher in BioML @MSFTResearch (@MSRNE). He/him/他. 🇹🇼
Jue Wang @jueseph
2K Followers 760 Following Research scientist @googledeepmind. Formerly @UWproteindesign @ginkgo @HMS_SysBio.
Andrew White 🐦�... @andrewwhite01
27K Followers 2K Following Head of Sci/cofounder @FutureHouseSF. Prof of chem eng @UofR (on sabbatical). Automating science with AI and robots in biology. Corvid enthusiast
Tom Blomfield @t_blom
66K Followers 883 Following Group Partner at @ycombinator Cofounded @gocardless and @monzo
Tony Kulesa @kulesatony
9K Followers 2K Following biotech startups @pillar_vc and @petribio Prior: @MIT, @BroadInstitute
Yunha Hwang @Micro_Yunha
4K Followers 1K Following Building genomic intelligence, Asst Prof @MITBiology, @MITEECS, @MIT_SCC, Chief Scientist @tatta_bio https://t.co/gF8HeJo5hU
Kamil Pabis @Aging_Scientist
2K Followers 734 Following Singapore based Aging Researcher. @vita_dao, longevity advocacy, progress studies, city planning, open science, AI, democracy & economics of SE asia.
Kresten Lindorff-Lars... @LindorffLarsen
15K Followers 2K Following Protein and coffee lover, father of two, professor of biophysics and sudo scientist at the #LinderstrømLang Centre for Protein Science 🇩🇰
Hyung Won Chung @hwchung27
38K Followers 302 Following AI Research Scientist @Meta Superintelligence Labs. Past: @OpenAI / @Google Brain / PhD @MIT
Esben Kran @EsbenKC
851 Followers 1K Following I build systems for revolutionaries. @seldonai, @apartresearch, Juniper, ENAIS, AISA.
Patrick Kidger @PatrickKidger
11K Followers 213 Following I do SciML + open source! 🧪ML+proteins@ https://t.co/04dWAWzCyl 📚Neural ODEs: https://t.co/ODOKWjub5k 🤖JAX ecosystem: https://t.co/8kXzaG9XVf 🧑💻Prev. Google, Oxford
Amy Lu @amyxlu
4K Followers 2K Following Senior Research Scientist @IsomorphicLabs building AI for drug discovery. Prev: CS PhD @berkeley_ai, @PrescientDesign, @insitro, @UofT. 🇨🇦
Corin Wagen @CorinWagen
3K Followers 655 Following CEO + co-founder @RowanSci // ☧, husband/father, computational/organic chemist
Sam Rodriques @SGRodriques
15K Followers 192 Following Director and CEO at FutureHouse. Building an AI scientist. https://t.co/rQYoPOxsYo
Pranam Chatterjee @pranamanam
4K Followers 339 Following Generating biologics to program biology! 💻🧫 Assistant Professor at @Penn | Co-Founder @GametoGen and @UbiquiTxINC | Formerly @MIT '16 '18 '20 and @harvardmed
Demis Hassabis @demishassabis
488K Followers 146 Following Nobel Laureate. Co-Founder & CEO @GoogleDeepMind - working on AGI. Solving disease @IsomorphicLabs. Trying to understand the fundamental nature of reality.
Julie Kovacs @Kovac4186Julie
208 Followers 195 Following