My Research Highlight on a carbohydrate-based inhibitor that blocks peptidoglycan polymerization -- Bacteria lose a pep in their step rdcu.be/dGbj7 #glycotime pubs.acs.org/doi/10.1021/ja…

Work was a collaboration with @sjwill99 in Oz, @ronocdrofwarc in Germany , Sjoerd van der Post in Sweden, and Dominic Byrne in Liverpool #glycotime

New manuscript! "Expanding the repertoire of GalNAc analogues for cell-specific bioorthogonal tagging of glycoproteins". Congrats to @abdul_hzafar, Sandhya Sridhar, @BinevaGanka, @drAnnaCioce with @DavidHewings @StacyMalaker! #glycotime Preprint: chemrxiv.org/engage/chemrxi…

Happy to share our paper with @jflovell and Khushi Matta, showing that coupling GlcNAc to porphyrin derivatives enhances cell penetration and light-induced cancer cell death. #PDT #glycotime dlvr.it/T5kw95

🆕The @GlycanTrigger Coordinator, Prof @Salome_S_Pinho, has been appointed as Vice-President, alongside President @BSilva_Santos, to the Board of the @SImunologia for the next 4 years! 👏 They bring with them exciting new ideas and plans to boost #immunology in 🇵🇹 #glycotime

Coming up next week: 📅 May 8, 2024 🕒 3–4 pm CEST Online #BeilsteinTalk "Chemical precision tools to dissect protein #glycosylation" with @DrGlycoBen @TheCrick @impchemistry. Participation is FREE! Just register: 🔗beilstein-institut.de/en/talks/bioch… #glycotime #chembio #BeilsteinTalks

“…we discovered that the LPS receptor Toll-like receptor 4 (#TLR4) is specifically dependent on the oligosaccharyltransferase complex OST-A for N-glycosylation and cell-surface localization” #glycotime cell.com/cell/fulltext/…

Congratulations @a_s_ramirez and co-authors!!! #glycotime

Ana S. Ramírez @a_s_ramirez

4 days ago

Congratulations @a_s_ramirez and co-authors!!! #glycotime

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Happy to share a link to the final published version of our paper on the structural basis of bacterial IgG deglycosylation by EndoS2. Kudos to @mattiascollin for finding this fascinating enzyme. #glycotime doi.org/10.1016/j.jbc.…

@CarolynBertozzi @NatureCatalysis @RamonHu08403543 fantastic work by you and your team #glycotime on discovery of new chimera/dual function enzymes!

Characterization of a cool mucinase subtype bearing features of both glycosidases and proteases ⁦@NatureCatalysis⁩ #glycotime A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases | Nature Catalysis nature.com/articles/s4192…

#glycotime 🚨 Gut microbes have enzymes that break down the heavily glycosylated mucin protein of host animals, but known enzymes recognize only one glycan chain. Now, bioinformatic exploration has uncovered a family of mucinases that targets dense sugar residues‼️

Shinya Fushinobu @sugargroove

3 days ago

#glycotime 🚨 Gut microbes have enzymes that break down the heavily glycosylated mucin protein of host animals, but known enzymes recognize only one glycan chain. Now, bioinformatic exploration has uncovered a family of mucinases that targets dense sugar residues‼️

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Extremely happy to share that our work on how specific #gutbacteria modulate #mucus function under low-fiber #diet is now out in @natcomms! #gutmicrobiota #glycotime #probiotics #fiber nature.com/articles/s4146…

Invitation to participate for 🆓: Online #BeilsteinTalk "Chemical precision tools to dissect protein #glycosylation" with @DrGlycoBen @TheCrick @impchemistry on 📅 May 8, 2024 🕒 3–4 pm CEST. 🔗beilstein-institut.de/en/talks/bioch… #glycotime #chembio #BeilsteinTalks

#glycotime

Nature Communications @NatureComms

4 days ago

#glycotime

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