Prof. Shane Crotty @profshanecrotty
Vaccines and immune system scientist. Professor, La Jolla Institute for Immunology (LJI), a non-profit research institute @ljiresearch. PhD not MD. lji.org/labs/crotty/ La Jolla, San Diego Joined March 2016-
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Victor is a great follow
This study on response to Omicron after #SARSCoV2 vaccination provides some optimism re “original antigenic sin” biorxiv.org/content/10.110… TLDR: although response to Omicron dominated by preexisting B-cells, antibodies from these cells better at 6 months than 1 month. 🧵 below.
All thanks to @UCSanDiego @UCSDHealth— where you are lifted by a unmatched tradition of interdisciplinary research, great patient care programs, dynamic surrounding research institutes, beaches, palm trees 🌴, fish tacos 🐟 🌮 and above all, the most amazing students and trainees
All thanks to @UCSanDiego @UCSDHealth— where you are lifted by a unmatched tradition of interdisciplinary research, great patient care programs, dynamic surrounding research institutes, beaches, palm trees 🌴, fish tacos 🐟 🌮 and above all, the most amazing students and trainees
Seeing some discussion about this publication with a pretty catastrophic failure to understand/communicate the limitations of the work, so here's my best attempt at clarifying it 🧵 cdc.gov/mmwr/volumes/7…
Nice work @isaak_quast ! That’s a great graphic about the memory B cell re-recruitment 🙏🏼 @harrysutton93
Nice work @isaak_quast ! That’s a great graphic about the memory B cell re-recruitment 🙏🏼 @harrysutton93
Everybody keeps talking about antibody-escaping variants… Nice work from Andrew Godking is showing how magnitude of T cell response against SARS-CoV2 structural proteins (M,NP and Spike) correlates with protection against COVID-19 more than Ab. Go T cells nature.com/articles/s4146…
Carolyn Bertozzi – awarded the 2022 #NobelPrize in Chemistry – has taken click chemistry to a new dimension and started utilising it in living organisms. Her bioorthogonal reactions take place without disrupting the normal chemistry of the cell.
Two Nobel prizes for Barry Sharpless! Extraordinary! And well deserved. Congrats to our neighbors down the street @scrippsresearch !
Two Nobel prizes for Barry Sharpless! Extraordinary! And well deserved. Congrats to our neighbors down the street @scrippsresearch !
As usual, @EricTopol beat us to tweeting about our paper. 😂
As usual, @EricTopol beat us to tweeting about our paper. 😂
Thanks @PC_immuno !
I swear I wouldn’t use actually twice in once sentence when writing a manuscript
I swear I wouldn’t use actually twice in once sentence when writing a manuscript
Edward Nirenberg 🇺.. @ENirenberg
36K Followers 6K Following Views my own, but you can borrow them if you feel so inclined. Anti-disease. Big Nerd Energy. “A homework person.” Fun at parties. Antibody hoarder. he/him
Prof. Akiko Iwasaki @VirusesImmunity
219K Followers 2K Following We study antiviral immunity and viral disease pathogenesis. #COVID19 #longCOVID #vaccines @HHMINEWS @YaleIBIO @YaleMed @YaleCII President of @ImmunologyAAI
Jeremy Kamil is also .. @macroliter
25K Followers 5K Following He, him. CMV virologist exploring how viruses exploit glycoimmune checkpoints #Glycotime | Loves 🥾 🏔️ 🏕️| Y'all on Bluesky or Threads? Linktree below ⬇️
Bloom Lab @jbloom_lab
48K Followers 1K Following Lab studying molecular evolution of proteins and viruses. Affiliated with @fredhutch @HHMINEWS @uwgenome. @jbloomlab@bsky
Tom Peacock @PeacockFlu
50K Followers 1K Following Virologist. Viruses, Influenza, Coronaviruses and SARS-CoV-2. Typos are intenitonal. Fellow at @Pirbright_Inst and @ImperialInfect
Jasnah Kholin - 8964 .. @wanderer_jasnah
10K Followers 1K Following HKer. RNA Virologist working on nidovirus/immune system interactions. Insomniac. Life before death. Journey before destination. 一个健康的社會不該只有一種聲音. 解散警隊. ★ she/佢 ★
Daniel Griffin MD PhD @DanielGriffinMD
20K Followers 176 Following A physician-scientist, board certified in Infectious Disease w expertise in Global Health, Tropical Medicine, Parasitology, and Virology.
Michael Mina @michaelmina_lab
220K Followers 1K Following Physician-Scientist, MD,PhD. Immunology, Epidemiology, Infectious disease, Autoimmunity, Biotech, Diagnostics, Math. CSO, CMO. Past: Harvard Faculty. DM’s Open
Yunlong Richard Cao @yunlong_cao
19K Followers 409 Following Biochemistry & Immunology | Host Immune Response, Antibody Drug & Vaccine Design | PhD @Harvard | Assistant Professor at Peking University BIOPIC
Raj Rajnarayanan @RajlabN
17K Followers 694 Following Assistant Dean of Research and Associate Professor, NYITCOM at Arkansas State University | My Tweets are my own
Ryan Hisner @LongDesertTrain
22K Followers 838 Following Teacher "Be ruthless with systems and be kind to people." Michael Brooks, 1983-2020
Tom Wenseleers @TWenseleers
23K Followers 1K Following Professor @KU_Leuven - evolutionary biology, theoretical biology & biostatistics. Working with #insects, #microorganisms (incl. Covid) & #humans.
Danny Altmann @Daltmann10
26K Followers 2K Following Immunology Prof. Ed at OUP OxfordOpenImmunol, Imperial Coll research group with @BoytonRosemary. Co-author - https://t.co/TRqYKSl30V
Viki Male @VikiLovesFACS
24K Followers 2K Following Immunologist working on pregnancy at @ImperialCollege | equality and diversity in STEM | she/her | Because VikiLovesNKCells was too long for Twitter
Stuart Neil @stuartjdneil
16K Followers 1K Following Virologist. 🦠 HIV, EBOV, SARS2 and Flu interactions with their hosts. ‘Biodefense expert’ according to a hack
Andrew Croxford @andrew_croxford
28K Followers 571 Following Immunologist for about 20 years. Just opinions of mine, not representative of any company, foundation or affiliation.
AAI @ImmunologyAAI
23K Followers 738 Following The American Association of Immunologists is an association of scientists dedicated to advancing the knowledge of immunology. @J_Immunol & @ImmunoHorizons
Victora Lab @victora_lab
5K Followers 604 Following Laboratory of Lymphocyte Dynamics at @RockefellerUniv. Opinions are Gabriel’s own. @victora.bsky.social
Adrian Liston @LabListon
10K Followers 5K Following 🇦🇺🇧🇪🇬🇧👨🔬🌈 Professor of Pathology at @CamPathology @Cambridge_Uni. @ImmunolCellBiol Editor-in-Chief. Daddy
Lisa Shan LI @li_shan10
9 Followers 187 Following
LalaVomBerg @Lala000055
279 Followers 640 Following
たくみや @miyaz333
2 Followers 279 Following
Alberto Paniz Mondolf.. @Betopaniz
2K Followers 3K Following Internist/Pathologist/Microbiologist. Director of Molecular Microbiology at Mount Sinai. Addicted to books, good music and the jungle. Scout. Science official.
David Kay @KayDavid26867
90 Followers 2K Following President and CEO of #ROYALBANKOFCANADA. Member and board member of the @BusinessCouncilofCanada, and serve on the advisory board of Catalyst Canada.#Montreal
SilverChubs @ChubsSilver
52 Followers 151 Following Invest in the best asset class of all time - oneself.
Pam C @PammckC
882 Followers 722 Following Mom, wife, engineer, ice cream addict. Trying to focus on what I still can do versus what I can’t while sidelined with dysautonomia from Covid.
Mew | ♀♿️ @mewmasks
179 Followers 542 Following Community Worker🧸 Mask Up 😷🚿Married to Hot Showers 🚿 ⚡️Always in pain ⚡️ —— Yes I Can Park There ♿️
Rosi BN @rosi_bn
1 Followers 189 Following
Michael Alexander @Michaeltikus
888 Followers 2K Following I like animals 🐙 Zoology/Psych PG interested in nature connections, diving and tapirs. Member @Long_Covid / @RenegadeRes Lead contributor @wecrunchme LC-PLAN
Mostafa Salehi-Vaziri @msv_1985
19 Followers 66 Following Virologist studying Arboviruses and VHFs, Love nature & fueling my brain with books & movies #Science #Virology #Outdoors
Ellie @BaronPubel1652
428 Followers 3K Following proud us army… love dogs and hiking and not a lover of the spider’s. Please if you’re thinking of adding me up first ask yourself if you’re a gentleman 👌
AeroVirología Animal.. @AlesandroSherry
369 Followers 3K Following 8.000.000.000Humans Vs #Animal&HumanAeroVirology #SARS2,FLU,#RSV,... Protect -MUCOSA(Nose,Mouth,Eyes) -BROKEN SKIN #TransDisciplinary #OneHealth #UnaSalud
valeria @ValequinVq
47 Followers 4K Following
Hsuan-Yuan (Sherry) W.. @HsuanYuanWang1
43 Followers 61 Following I am an Immunology Ph.D. student at Duke studying cytomegalovirus vaccine.
Austin Guo @jingao_austin
0 Followers 2 Following
Research & Updates on.. @VACCINES_2024
182 Followers 2K Following Sciinov Group invites you to join us at "Research & Updates on Vaccination & Covid-19" on 17-18 June, 2024 | Online Event
jack Ye @pengling86
70 Followers 561 Following
Sylvia @Sylvia13497722
3 Followers 60 Following
ComplexLife @EarthCells
99 Followers 194 Following
Immuno Centar @Immuno_Centar
24 Followers 58 Following Imunologija | Medicina zasnovana na dokazima | Konsultativne usluge
Lianyu Huang @Lianyu_H
0 Followers 31 Following A virology-loving, Switch game-playing, anime enthusiast on a never-ending adventure! 🦠🕹️🎮🏞️
✨⭐️✨ @Wish2dream23
409 Followers 2K Following Please wear a n95 respirator (mask) 😷 to protect the vulnerable AKA everyone. #covidisNOTover #SARS2isAirborne
Jennings N Darbishire.. @digitalme4
867 Followers 3K Following Tech, Bikes, Music, Food. Ex-Datsun driver. Winning! On Mastadon @DigitalMe
Florin Stoica @FlorinS34764211
26 Followers 24 Following
JOURNAL OF MUCOSAL IM.. @research52518
94 Followers 935 Following
MRC TIDU @MRC_TIDU
2K Followers 2K Following Latest news and announcements from the MRC Translational Immune Discovery Unit (previously called the MRC Human Immunology Unit) @MRC_WIMM
Davanda @Davanda23da
110 Followers 2K Following
Helge Dorfmueller @helged80
475 Followers 629 Following Father, husband, group leader at Uni of Dundee working mainly on #StrepA, opinions are my own
Jalal Alshaweesh @JAlshaweesh
9 Followers 161 Following
FOCIS @FOCISimmunology
2K Followers 343 Following The Federation of Clinical Immunology Societies exists to improve human health through immunology, providing novel education & cross-discipline networking opps.
Andrew Nosal @AndrewNosal
2K Followers 579 Following Associate Professor of Biology at @PLNU & marine biologist at @Scripps_Ocean, interested in #sharkscience, #animalbehavior, #scicomm, & #diversityinSTEM. 🇵🇷
hannah sach @hannah_chan
11 Followers 53 Following
Takuya Hemmi @t_hemmi_v
8 Followers 42 Following TUS AB → KU LiMe / virology vaccinology / Ph.D student
Ricardo Ballesteros-R.. @Sys_Biology
35 Followers 291 Following #Oncology #SystemBiology #Network #Pharmacology #Systemimmunology #Pharmacometrics
AOrdo @AOrdo3
29 Followers 139 Following
Marina Costa Fujishim.. @submarinahere
393 Followers 364 Following A curious mind. ☕️ PhD student in Immunology at @UM_immu interested in mucosal immunology and microbiome. she/her 🇧🇷🇨🇦
Dorian McILROY @dorian_mcilroy
35 Followers 41 Following Brexile in Nantes Opinions expressed here are my own, and do not reflect the views of my employer.
priya goyal @goyal_priya26
14 Followers 586 Following #Ph.D student #Virologist #Host virus interaction #Regulation of host cell glycolysis in Influena virus infection #Open for Post-doctoral position
Imperial INVaR @Imperial_INVaR
205 Followers 134 Following Imperial Network for Vaccine Research is involved in promoting collaborations and research of vaccines.
Eric Wang @ericjidaw
41 Followers 67 Following
Turvey lab @TurveyLab
1K Followers 681 Following Dr. Stuart Turvey and the Turvey lab are commited to improving child health through research. Our research transforms lives. There is urgency to what we do!
Teresa @Teresa40334182
20 Followers 2K Following
Michael MΞrritt @devm0de
255 Followers 2K Following software engineer @cisco, dev ops, web dev, backend and security focused. #beach #skiing #memes
上山下海 @alternate_xyz
35 Followers 461 Following
Grace @GraceSciences
210 Followers 5K Following
Edward Nirenberg 🇺.. @ENirenberg
36K Followers 6K Following Views my own, but you can borrow them if you feel so inclined. Anti-disease. Big Nerd Energy. “A homework person.” Fun at parties. Antibody hoarder. he/him
Prof. Akiko Iwasaki @VirusesImmunity
219K Followers 2K Following We study antiviral immunity and viral disease pathogenesis. #COVID19 #longCOVID #vaccines @HHMINEWS @YaleIBIO @YaleMed @YaleCII President of @ImmunologyAAI
Bloom Lab @jbloom_lab
48K Followers 1K Following Lab studying molecular evolution of proteins and viruses. Affiliated with @fredhutch @HHMINEWS @uwgenome. @jbloomlab@bsky
Tulio de Oliveira @Tuliodna
61K Followers 650 Following Director of CERI (Centre for Epidemic Response & innovation) @StellenboschUni and KRISP (KZN Research Innovation & Sequencing Platform) @UKZN. Tweets my own.
Daniel Griffin MD PhD @DanielGriffinMD
20K Followers 176 Following A physician-scientist, board certified in Infectious Disease w expertise in Global Health, Tropical Medicine, Parasitology, and Virology.
Michael Mina @michaelmina_lab
220K Followers 1K Following Physician-Scientist, MD,PhD. Immunology, Epidemiology, Infectious disease, Autoimmunity, Biotech, Diagnostics, Math. CSO, CMO. Past: Harvard Faculty. DM’s Open
Dr Emma Hodcroft @firefoxx66
80K Followers 825 Following Die Virenjägerin! 🏹🧬 Co-developer of @nextstrain! Using phylogenetics, I study viruses. I like ✈️ & 🐈 @[email protected] @firefoxx66.bsky.social
Tom Wenseleers @TWenseleers
23K Followers 1K Following Professor @KU_Leuven - evolutionary biology, theoretical biology & biostatistics. Working with #insects, #microorganisms (incl. Covid) & #humans.
Vincent Racaniello @profvrr
180K Followers 388 Following 🌍 Earth's Virology Professor 🎙 https://t.co/Z9gk3N2HaS host 🎥 https://t.co/GhFkgkbJBI
Danny Altmann @Daltmann10
26K Followers 2K Following Immunology Prof. Ed at OUP OxfordOpenImmunol, Imperial Coll research group with @BoytonRosemary. Co-author - https://t.co/TRqYKSl30V
Viki Male @VikiLovesFACS
24K Followers 2K Following Immunologist working on pregnancy at @ImperialCollege | equality and diversity in STEM | she/her | Because VikiLovesNKCells was too long for Twitter
AAI @ImmunologyAAI
23K Followers 738 Following The American Association of Immunologists is an association of scientists dedicated to advancing the knowledge of immunology. @J_Immunol & @ImmunoHorizons
Paul Offit @DrPaulOffit
50K Followers 293 Following Infectious disease pediatrician and author of "Tell Me When It's Over" https://t.co/YlNp6Np5jt
Victora Lab @victora_lab
5K Followers 604 Following Laboratory of Lymphocyte Dynamics at @RockefellerUniv. Opinions are Gabriel’s own. @victora.bsky.social
Immunity @ImmunityCP
64K Followers 339 Following Cutting-edge research in immunology from around the world, and commentaries by thought leaders. Cell Press. Tweets by Immunity editors.
JExpMed @JExpMed
32K Followers 1K Following The Journal of Experimental Medicine publishes immunology, cancer, stem cells, microbial pathogenesis, vascular biology, neurobiology. Est. 1896 - @RockUPress
Paul G Thomas @PGTimmune
5K Followers 3K Following Department of Host-Microbe Interactions, St. Jude Children's Research Hospital
Daniele Focosi, MD Ph.. @dfocosi
6K Followers 55 Following Hematologist, PhD in Virology, MSc in clinical trials, transfusion physician. Opinions are mine. Retweets/likes ≠ endorsements
Deepshika Ramanan @ShikaRamanan
883 Followers 181 Following Immunologist. Damon Runyon Postdoctoral Fellow @harvardmed. Mom
Goran Bajic, Ph.D. @gogo_science
2K Followers 488 Following I take pictures of molecules. Assistant Professor at Mount Sinai #vaccines #immunity #viruses #antibodies #cryoEM 🏳️🌈
Isaak Quast @isaak_quast
151 Followers 215 Following Senior Scientist and Group Leader studying the germinal centre response in the Tarlinton lab @MonashImmPath @MonashCCS, NHMRC Peter Doherty Fellow
The Nobel Prize @NobelPrize
1.1M Followers 509 Following The official Twitter feed of the Nobel Prize @NobelPrize #NobelPrize
Harry S @harrysutton93
249 Followers 304 Following Post doc in the Crotty lab at the La Jolla Institute of Immunology. Trying to help imagine life without disease a single cell at a time
Carolina Lucas @carolilucas
3K Followers 479 Following Assistant Professor @YaleIBIO ImmunoVirus ❤️ Alum @Virusesimmunity lab | #womeninSTEM 🇧🇷/🇺🇸
Garry P. Nolan @GarryPNolan
81K Followers 71 Following A world sans hues is a dream yet told. Cancer Bio, Immunology, Bio-Computation, 🏳️🌈, UAP/SETI. Negative posters blocked w/o pause.
Moderna @moderna_tx
150K Followers 558 Following Our mission is to deliver the greatest possible impact to people through mRNA medicines.
Jenna Guthmiller @GuthmillerJenna
2K Followers 1K Following Assistant Professor at @CUAMCImmu_micro. Influenza viruses, memory B cells, and regulation of humoral immunity
Michael Worobey @MichaelWorobey
12K Followers 260 Following Viruses. Pandemics. Professor and Head of Ecology and Evolutionary Biology at the University of Arizona. Tweets mine.
Allison Krug MPH @KrugAlli
7K Followers 2K Following Epidemiologist + pro coach specializing in health & wellness, runner, rider, hiker, hockey mom. Mil spouse. Passion for kids and education. 日本に4年間住んでた。
Christopher Barnes, P.. @cobarnes27
4K Followers 1K Following Assistant Professor of Biology @Stanford | Father | Structural Biologist ❄️🔬| Mentor | Advocate✊🏾| Eater and cooker of southern food 😋#BLACKandSTEM👨🏾🔬
The Bjorkman Lab @bjorkmanlab
2K Followers 323 Following Bjorkman lab @Caltech / Managed by Bjorkman Lab Members
Sarah Caul @Sarah__Caul
5K Followers 190 Following MBE. Currently working on PSP Review. Previous Head of Mortality @ONS during the pandemic. All views are my own, re-tweet and like doesn't imply endorsement.
Baumjohann Lab @BaumjohannLab
1K Followers 1K Following Research on T helper cells in #Immunity and #Autoimmunity in the lab of Dirk Baumjohann #TfhCells #GerminalCenters @ImmunoSens @UniklinikBonn @UniBonn
Daniel Mucida 🍉 @danmucida
8K Followers 1K Following Immunologist @RockefellerUniv @HHMINews, anti-racist, anti-fascist, anti-apartheid 🇧🇷🇺🇸🇵🇸🇨🇺 opinions are my own and do not reflect those of my employers
Carolyn Moderbacher @CModerbacher
20 Followers 15 Following
Waggoner Lab @LabWaggoner
7K Followers 4K Following Research lab of Dr. Stephen Waggoner. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer.
Camp Half-Blood Updat.. @chbupdates
66K Followers 96 Following Unofficial updates from Camp Half-Blood. ⚔️
Mondo Mascots @mondomascots
195K Followers 4K Following Celebrating the weird, wonderful mascots of Japan. My Instagram: https://t.co/lzuob9XErO . ゆるキャラが大好きなイギリス人です。
Verified @verified
4.2M Followers 2 Following Individuals can get a blue checkmark with @Premium. Organizations can sign up for Verified Organizations here: https://t.co/mIt8n1qdTe
Jennifer Juno @scientist_JJ
579 Followers 664 Following 🇨🇦 in 🇦🇺 Scientist. Geek. Feminist. She/her. Lab head (@viralvaxlab) at @TheDohertyInst and @Unimelb. I stare at dots a lot.
Emily Waltz @EmWaltz
1K Followers 303 Following Journalist, truth seeker, mother. Associate Editor @IEEESpectrum covering power & energy. Former biotech reporter for @Nature journals. Geek out with me!
Infection Prevention .. @RnInfection
596 Followers 507 Following Infection prevention USA based x 42 years. MM personal interest. Views and opinions my own. @[email protected]
Parham Rad @P1RAD
152 Followers 269 Following Immunology, Oncology and the Antidote to Dystopia. Traversing Science @LJIresearch
Iannacone Lab @iannaconelab
3K Followers 679 Following Our lab @MyUniSR and @SanRaffaeleMI seeks to dissect the complex dynamics of immune responses to pathogens and tumors. #Immunology #HBV #SARSCoV2 #COVID19
HandLab @thehandiestlab
3K Followers 761 Following Microbiome & the immune system: best frenemies forever. Univ. of Pittsburgh/UPMC Children's Hospital/R.K. Mellon Institute for Pediatric Research #immigrant
Carla Nowosad @CarlaTheNove
1K Followers 939 Following Assistant Professor, #MucosalBCellLab @NYUgrossman. Poorly adjusted Brit in NYC. Constantly thinking about Germinal Centers & avoiding matcha. Views all mine
neil_ferguson @neil_ferguson
129K Followers 32 Following Infectious disease modeller/epidemiologist. Director of J-IDEA and the MRC Centre for Global Infectious Disease Analysis
The Virus Monologues�.. @virusmonologues
5K Followers 1K Following FREE PALESTINE : STOP ZIONIST GENOCIDE : FREE PALESTINE Wendy Burgers: Viral immunologist, Prof @IDM, University of Cape Town
msdiamondlab @msdiamondlab
2K Followers 622 Following We are the members of the Diamond lab at WUSM: cutting edge virology, immunology, and microbiome research, and antiviral vaccine and therapeutics development.
Freja Kirsebom @freja_kirsebom
7K Followers 688 Following Senior epidemiologist - COVID-19 vaccines @UKHSA. PhD in the immunology of respiratory viral infections @imperialcollege.
Teddy Yewdell @TYewdell
2K Followers 886 Following Group Leader/Principal Scientist @Genentech. B cells, autoimmunity, immune memory, tiki taka & geggenpressing 🐘: @[email protected]
Robert Johnston @rjj_hwy1
190 Followers 396 Following Cancer Immunology | Drug Discovery | Reverse Translation | Highway 1 enthusiast | @genentech
Prof. Christina Pagel @chrischirp
204K Followers 950 Following Prof Operational Research @UCL_CORU, health care, women in STEM. Member of @independentsage. Tweets personal. chrischirp at bluesky. https://t.co/nNW5zMenx2
Mallory Harris (@mala.. @malar0ne
4K Followers 3K Following thinking about infectious diseases & misinfo @ Stanford || PhD student || I check this website and dms rarely nowadays she/her
Michal Tal, PhD @ImmunoFever
13K Followers 10K Following Immunoengineer @MITdeptofBE captivated by #inflammation, #SexDifferences #Lyme, #COVID, and planetary health. prev/ @Yale, @Stanford. @immunofever.bsky.social
MedPage Today @medpagetoday
77K Followers 6K Following Healthcare is complicated. We explain it. #MedPageToday Retweets, likes, and comments are not endorsements.
Prof. Peter Doherty @ProfPCDoherty
116K Followers 808 Following Immunologist, Nobel laureate and author of THE BEGINNERS GUIDE TO WINNING THE NOBEL PRIZE, THE KNOWLEDGE WARS & AN INSIDER'S PLAGUE YEAR
Katalin Kariko @kkariko
70K Followers 262 Following I am a scientist, working on the therapeutic use of in vitro transcribed mRNA.
Locci Lab @LocciLab
1K Followers 303 Following We study the biology of T follicular helper cells and germinal centers in health and disease. Opinions are Michela's. @Penn @Pennmedicine @[email protected]
Sharon L Schendel @slschendel
101 Followers 425 Following Biophysicist who stumbled into virology; love colicins; bowler b/c golf takes too long; write for fun; Rotarian; Hoosier; Worry less,paddle more 🚣Views my own
uché blackstock, md @uche_blackstock
140K Followers 5K Following mama, physician, founder & @nytimes best-selling author, LEGACY: A Black Physician Reckons with Racism in Medicine 👩🏾⚕️🩺 @vikingbooks 🔗 in bio👇🏿!
Representation matters 😀 #SLB2022 #BlackinImmuno
Here are a few slides that elaborate on this topic: slides.com/jbloom/sars2-v…
Here is an updated plot showing the remarkable similarity in the patterns of where spike mutations occur in the #SARSCoV2 variant BQ.1.1 versus the long terms hotspots of evolutionary change in human CoV-229E.
Omicron keeps finding new evolutionary tricks to outsmart our immunity - @K_G_Andersen and other experts discuss what the variant landscape may look like in the future. @NPR @robsteinnews npr.org/sections/healt…
First up, Australia: After a close start, BQ clan is out to an early lead, at 7% frequency. XBB clan is also growing, but more slowly and only up to 3.5%. Sample sizes are quite consistent up to 12 Oct, although some smaller states are lagging (WA, SA, TAS).
There are some positive signs in Germany's most recent SARS-CoV-2 genomic data. * The share of BQ.1.1 doubles every 10d, but ... * Overall cases have solidly declined (-5% per day) * Absolute BQ.1.1's numbers increased only slowly (0-5% per day)
In some ways, the anti-science rhetoric is even more intense now than it was in the last election cycle. Read the latest from @owermohle trib.al/4ZBXGya
🎉My turn! Super excited to join @KECKSchool_USC @uscnorris as an Assistant Professor in early 2023. My lab will decode inter-cellular communication and intra-cellular molecular programming to develop precision immune therapeutics. Stay tuned for lab website and hiring! 1/n
Always nice to see my son’s apple return home from it’s daily school outing
For what it's worth. The highest level of BQ.1.1 I've seen from wastewater so far was about 30%. That was from a sample collected over 2 weeks and the sewershed still isn't showing any meaningful increase in total viral levels.
I wish one of the takeaway messages from the pandemic was IF YOU HAVE A COLD STAY AWAY FROM OTHER PEOPLE. People will sneeze or cough and then yell across the room “It’s not COVID, I took a test.” Okay bro, I don’t want to catch your flu or RSV either.
Just published @ScienceMagazine A nasal vaccine booster (after primary vaccination) induces mucosal immunity —IgA, memory B and T cell—against the sarbecovirus family in the experimental model science.org/doi/10.1126/sc… by @VirusesImmunity @tianyangmao and team @YaleIBIO @YaleMed
Very hopeful sign France is the 1st country in Europe to see the BQ.1.1 variant dominance (>50%). So far, so good. {Booster rate in France is 65%, US 41%)
.@deeptabhattacha is right. 3-5 weeks is “too short to reach firm conclusions.” At first, you’ll only boost existing antibodies. It takes months for our immune system to update its B cells to make Omicron-specific antibodies. @robsteinnews npr.org/2022/10/25/113…
@macroliter @EricTopol Some of the discrepancy could also be due to looking at memory B cells versus serum antibodies. Beneficial adaptations in B cells may not clearly manifest in serum antibodies until next exposure. See below from discussion of Kaku et al:
But unique aspect of Kaku et al study is to compare Omicron neutralization by antibodies from B cells at 1 versus 6 month after breakthrough infection (Cao et al only looked 1 month). After 6 months, antibodies have affinity matured to be much more potent against Omicron!
Importantly, this finding is shared across the other two studies: the cross-reactive antibodies elicited by Omicron boosting generally don’t neutralize Omicron as well as they neutralize the “old” viral strain:
It is now established that response to Omicron booster vax or breakthrough infection is dominated by boosting pre-existing B cells; see below. (Studies differ on if it’s just dominated or overwhelmingly dominated, maybe due to differences including CoronaVac vs mRNA vax?)
The study is by @chengzi_kaku & @LauraWa27423872, w contributions from others including @tylernstarr and myself. It is highly complementary to recent studies by @yunlong_cao et al (x.com/yunlong_cao/st…) and @TheBCellArtist (x.com/thebcellartist…).
This study on response to Omicron after #SARSCoV2 vaccination provides some optimism re “original antigenic sin” biorxiv.org/content/10.110… TLDR: although response to Omicron dominated by preexisting B-cells, antibodies from these cells better at 6 months than 1 month. 🧵 below.
Trends for United States
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