Rahul Prasai @rahulprasai
pharma commercial strategy; @unc @kenanflagler alum; here for all biotech, current event, and sports content; tortured phx suns & tottenham fan; views my own. Washington, D.C. Joined April 2024-
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𝐂𝐡𝐚𝐧𝐝�.. @CParkMD
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is this particular to kevin? outside of steph, this seems to apply to an entire generation, including the defining player of this era.
I don't know what KD wants in a coach. Whatever it is, he hasn't found it since OKC, if he had it there. He just never seems happy with anyone that's coached him. Maybe that really is a them problem. I just don't know why it's been such a big issue place to place.
@NicoGagelmann @drkeithsiau @Satyayadav__ @arshiet @drsanjeev1980 @anujtiwari11 Also seems to have a complex karyotype 😭😭
TP53 mutated cancer against any therapy😰
Disease-Specific Hashtags [CTO] for Online Communication About Cancer Care [11/5/15] - @subatomicdoc et al. @JAMAOnc ow.ly/UiZ81
Healthcare Hashtag Project - via @symplur @healthhashtags symplur.com/healthcare-has…
@WindyCOYS Pretty sure he just doesn’t want to publicly throw Jedinak under the bus. He’s not Stevie Wonder he 100% knows we have a problem defending set pieces
"He was outstanding. He's a World Cup winner and I've just got to get some of what's in him into some of the others." Postecoglou on Romero ⬇️ theathletic.com/live-blogs/pre…
Have rarely season Postecoglou that angry after a game this season. Says the rest of the players need to be more like Romero.
Assuming Arsenal and City keep winning, City’s visit to Spurs on May 14 is going to be so weird. Most of the home fans will presumably be desperate not to win
Biggest summer signing for us will be a set piece coach.
I was too busy with Arsenal Spurs, I’ve just seen Bournemouth beat Brighton 3-0. Andoni once again yeah..
Spurs 3 main issues - final 3rd ball retention - defending transitions - defensive set pieces 🧵 on how to fix it (good news is it won’t be that difficult as long as they’re smart) Spurs are very good at lots of things. Need to fix these three
Hard to digest. But if you take the emotion, the scum and the occasion out of it there were a lot of positives to take from that second half. We’re far from the finished article but to be 3-0 down and show that much fight represents how much the players believe in Ange’s project
If we lose today (& there's a good chance we will) there are going to be some hysterical takes about Ange & his inflexibility, the quality of the squad, the gap between us & them. The thing to remember is that it's just one game (albeit, obviously, a huge one for us as fans).
Book went from the best off-ball guard in the league being asked to completely change his position and put up 27 and 7 on 61% ts on a team that was constantly in turmoil Then had to go to the playoffs and played one of the better defenses of the modern era and he’s not that guy?
I gave Book benefit of the doubt but I said on my priv in January Don was playing like SG1 this year and nothings changed since then to make me think differently
If you're framing this defeat as a lack of guts, energy, motivation, tactical nous... well, I staunchly believe you're wrong. A really rough non-penalty decision on Kulusevski that was instantly punished, and Spurs being Spurs on set pieces. So much to enjoy about Ange's Spurs.
excited for May awareness for #bladdercancer honored to serve mutual mission with @BladderCancerUS joined by @JLWrightMD patient advocates, survivors, community! Join us for annual walk on May 18: secure2.convio.net/bcani/site/TR/… @arkhaki @BLawenda @OncoAlert @spsutkaMD @CChuMD
Answer: in terms of potency, DM1 (maytansine derivative) >> DXd, SN-38 & doxo. The ⬇️ potency of DXd/SN38, however, allowed to include them in DAR 8 ADCs w/ cleavable linkers, among the reasons why T-DXd > T-DM1 in DB03. europepmc.org/article/pmc/pm… nature.com/articles/s4146… @raffcolo
Which of the following ADC payloads is more potent?
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