Uday Bikkasani @udaybb
Global CTO & Head of Technology Infrastructure at Novartis | #AI #Infrastructure #Data #Digital #IT #CTO | all opinions are personal Hyderabad, India Joined December 2008-
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The most important AI paper of 2025 might have just dropped. NVIDIA lays out a framework for Small Language Model agents that could outcompete LLMs. Here’s the full breakdown (and why it matters):
4 stages of training LLMs from scratch, clearly explained (with visuals):
We live in a brief and fascinating moment right now where there’s an insanely wide gap in productivity between two people just based on the tools they use and their specific workflows with AI. Just a few variables can be the difference between getting a 25% boost in productivity…
R.I.P paid courses... You can use any LLM like ChatGPT, Gemini, or Claude to build a custom course on any topic or subject. Here’s the mega prompt that we use to get world-class education for free:
Knowledge begets more knowledge, algorithms optimising other algorithms - we are using AlphaEvolve to optimise our AI ecosystem, the flywheels are spinning fast...
Knowledge begets more knowledge, algorithms optimising other algorithms - we are using AlphaEvolve to optimise our AI ecosystem, the flywheels are spinning fast...
if you are not skillsmaxxing with o3 at minimum 3 hours every day, ngmi
o3 answers the question I ask all new models: "You have consumed more information than anyone in the history of the world and you've demonstrated an extraordinary ability to make connections among them. What are the most important non-consenus or even not-yet-hypothesized things…
The time is right for another massive unlock: Tokenisation of land assets. To understand how this can turbocharge the economy, see👇 Full video here: youtu.be/mHE3zaaVo9c?si…
Vibe Engineering 🫡
Think about it—We'd never hand out $100 bills to strangers on the street, but we'll readily give an hour of our day to a pointless meeting or mindless scrolling. To live the lives we truly want, we must treat our time with the same (if not more) reverence as we do our money.
Overheard in Silicon Valley: "My biggest lesson from the last year is just, it’s all going to happen. All my childhood dreams of space colonies and brain interfaces and AI and robots. Everything is just… going to happen."
Daily walks help clear your mind
I read Google's paper about their quantum computer so you don't have to. They claim to have ran a quantum computation in 5 minutes that would take a normal computer 10^25 years. But what was that computation? Does it live up to the hype? I will break it down.🧵
New NotebookLM updates, rolling out today: 🎧Pass a note to the hosts – you can now click on ‘Customize’ in Audio Overviews to give additional instructions, such as focusing on a specific topic, source, or even adjusting the audience it’s optimized for. 🎧You can now minimize…
You can learn every single thing that made this possible.
You can learn every single thing that made this possible.
I don't recall another time in CS history where a result like this is obvious to the point of banality to one group. And heretical to another.
The holy grail of Local AI: 🔓Open Source 🏃♀️Runs Fast 💻Runs on your machine 🌐Runs on all machines @mozilla is leading the charge on the new local AI ecosystem: @JustineTunney’s work on @llamafile and @stlhood announced sqlite-vec & $100k in non-dilutive funding for all local…
The more I use Llama 3 the more I think that Zuck may have just killed OpenAI and all other large proprietary AI vendors. The gap between latest GPT4 and Llama 70b is virtually non existent. Even if OpenAI releases GPT5 now, 400b Llama 3 is still training and will most likely be…
AI Agents have the potential to democratize knowledge work in the same way that SaaS democratized software. And as we've seen in the past couple of decades with software, every time you make a service cheaper and more available, you dramatically increase the size of the total…
Introducing Meta Llama 3: the most capable openly available LLM to date. Today we’re releasing 8B & 70B models that deliver on new capabilities such as improved reasoning and set a new state-of-the-art for models of their sizes. Today's release includes the first two Llama 3…

Rylee James @nW1H46RSgySrT
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Deborah @yt1occ506192163
0 Followers 149 Following This steady daily income has doubled my weal th. I easily make $200 a day. Login: black89 Password: bk2882 Website: https://t.co/IwdCKHYEUa
Bala Pillai @balapillai
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navfinallyme @Navkanth1
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Eva Valle Maestro @maes_trova
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花🍻@ネトゲ(�... @dorungi1974
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Jay Peethambaran @techanschauung
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bodhi @antarshukhah
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srinath reddy @srinath_ds
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Devasish Bora @DevasishBora
137 Followers 770 Following Lazy Twitterati. Mostly consumes content and RT. I share my opinion when I strongly feel and believe on any topic
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Asperitas Consulting @Asperitascloud
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枫 Infinity.icp @Infinit64049038
197 Followers 764 Following Distrikt: https://t.co/mtinDicu7t DSCVR: …https://t.co/0PyWs6vtbj
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118 Followers 2K Following I want to be a good example of a good human being. Adventure, travel, music.
David Scozzafava @ScozzafavaDavid
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Yann LeCun @ylecun
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Akshay 🚀 @akshay_pachaar
227K Followers 484 Following Simplifying LLMs, AI Agents, RAGs and Machine Learning for you! • Co-founder @dailydoseofds_• BITS Pilani • 3 Patents • ex-AI Engineer @ LightningAI
Fundstrat Capital @FundstratCap
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Kunal Shah @kunalb11
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tobi lutke @tobi
416K Followers 2K Following @Shopify CEO by day, Dad in evening, hacker at night. Aspiring comprehensivist. (tweets auto delete eventually) retweet=noteworthy share, not endorsement
Olivia Moore @omooretweets
67K Followers 842 Following Partner @a16z and twin to @venturetwins | Investor in @happyrobot_ai, @krea_ai, @tomaauto, @partiful, Salient, @scribenoteinc & more
This You? @Thiss_Youu
208K Followers 14 Following "We do a little trolling". DM or tag me for submissions.
Apoorva Govind @Appyg99
32K Followers 1K Following Founder @BesteverAI. Ex @Ubereats. Previously @Apple. Technology Syster. Substack https://t.co/NOfQ180iK5
Ronald P. Karlsberg M... @RonKarlsbergMD
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Joe Lonsdale @JTLonsdale
235K Followers 478 Following I'm an entrepreneur, investor, & philanthropist. I founded @PalantirTech @Addepar @UAustinOrg @8VC & other mission-driven orgs. Bold policy @InstituteCicero
Donald J. Trump @realDonaldTrump
108.8M Followers 53 Following 45th & 47th President of the United States of America🇺🇸
Tesla AI @Tesla_AI
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Jeffrey Emanuel @doodlestein
24K Followers 10K Following Former Quant Investor, now building @lumeraprotocol (formerly called Pastel Network) | My Open Source Projects: https://t.co/9qbOCDlaqM
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203K Followers 645 Following Managing Partner & CIO @Compcircle .Passionate about sports ,markets, politics n movies. Views on mkts personal
Deedy @deedydas
205K Followers 5K Following VC at @MenloVentures. Formerly founding team @glean, @Google Search. @Cornell CS. Tweets about tech, immigration, India, fitness and search.
Dylan Patel @dylan522p
94K Followers 941 Following SemiAnalysis Boutique AI & Semiconductor Research and Consulting DMs are open for consulting, quotes, or to talk shop
Tesla Optimus @Tesla_Optimus
561K Followers 11 Following A general purpose, bi-pedal, humanoid robot capable of performing tasks that are unsafe, repetitive or boring.
John Rush @johnrushx
108K Followers 3K Following I run the most automated org on earth, using the AI Agents I built. @unicornplatform @indexrusher @listingbott @seobotai https://t.co/QIghafVlCy 24 startups → https://t.co/1ML5MmAQ7X
Figure @Figure_robot
141K Followers 1 Following Figure is an AI Robotics company building the world's first commercially viable autonomous humanoid robot.
Dumb Money @DumbMoneyTV
49K Followers 27 Following We are Dumb Money. 3 friends who turned tens of thousands into tens of millions. 👤 @DaveHanson 👤 @ChrisCamillo 👤 @Jordan_Mclain
Chris Camillo @ChrisCamillo
186K Followers 428 Following Being smart isn’t as important as being smart in a different way than others. The $20k to $60M guy in Unknown Market Wizards who’s going all in on humanoids.
Rob Henderson @robkhenderson
176K Followers 806 Following Best-selling author of "Troubled: A Memoir of Foster Care, Family, and Social Class" | Senior Fellow, @ManhattanInst | All Views My Own
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488K Followers 146 Following Nobel Laureate. Co-Founder & CEO @GoogleDeepMind - working on AGI. Solving disease @IsomorphicLabs. Trying to understand the fundamental nature of reality.
Google DeepMind @GoogleDeepMind
1.2M Followers 279 Following We’re a team of scientists, engineers, ethicists and more, committed to solving intelligence, to advance science and benefit humanity.
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878K Followers 0 Following Popped bubbles as we saw them, including our own. We expressed strong opinions. Not investment advice.
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