$BPMC looking to start a position. Really excited for early look at BLU-701 and BLU-945. I like the combination idea to drive deep and and durable responses, potentially covering multiple acquired resistance mutations. Along with the ability to control CNS metastasis.
The hospital system and doctors are partly to blame for the underuse of monoclonals, that can pretty much save most COVID death. I hear them complaining about full ICU’s but they won’t put an infusion tent in the parking lot. Tragedy. Govermment should have ordered them.
Bicycle Therapeutics $BCYC has just fired a shot-heard-round-the-world, threatening to disrupt a huge technology platform in the biotech industry.
Here's a play-by-play on David vs. Goliath, taking on antibody-drug conjugates!
Thread below🧵
❗️BREAKING at @AACR#Targets21: Mirati Therapeutics has disclosed the structure of MRTX1133, their reversible KRAS G12D inhibitor. Fantastic story. Plus hints of a new pan-KRAS inhibitor. Congratulations!
Today has been 🍿
War in BioTwitter and blood and gold in the streets.
Had a wild ride on a $BCYC and watched a Sheep fight a Scorpion.
Thanks all for the fun & commentary
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