Bio_Strand @Bio_Strand

Passionate about oncology research and new biotech advances. Side tracked by digestible *shiny objects* in genetics, synthbio, public health and data sci. Cambridge, MA Joined July 2019

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David R. Liu @davidrliu

5 years ago

Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative C•G-to-T•A point mutation in LMNA. 1/11 drive.google.com/file/d/1oH4W0z…

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Dr. Angela Rasmussen @angie_rasmussen

5 years ago

Hold up. The accidental low dose in the AstraZeneca trial was because Oxford insisted that NANODROP was more accurate than qPCR?! Ahahahahahahahahahahahaha reuters.com/article/us-hea…

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Michael Baym @baym

5 years ago

This is good advice for all science. Also the alt text: "We reject the null hypothesis based on the 'hot damn, check out this chart' test."

XKCD Comic @xkcdComic

5 years ago

This is good advice for all science. Also the alt text: "We reject the null hypothesis based on the 'hot damn, check out this chart' test."

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Neville Sanjana @nevillesanjana

5 years ago

A TWEETORIAL on our new CRISPR-sciATAC preprint. Our lab has been working on combining pooled CRISPR screens with single-cell chromatin accessibility for nearly 4 years so very happy to see this work finally out there in the world. biorxiv.org/content/10.110…

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Stuart Schreiber @SchreiberStuart

5 years ago

Lonafarnib, a farnesyltransferase inhibitor having a novel structure, approved for treatment of Hutchinson-Gilford Progeria Syndrome.

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Nik Joshi @Joshilabyale

5 years ago

A classic mistake is to start interpreting the results of your experiment before you’ve run all your samples. It can lead to unnecessary heartache or disappointment. Good idea to finish collecting your data before you try to decide what happened.

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Yale School of Public Health @YaleSPH

5 years ago

Dr. Anthony Fauci lays out three ways future scientific communicators can build trust: 1) Always go by the data 2) Admit when you don't know something 3) The goal is not to show how smart you are. It's to get people to understand what you're talking about. #FauciAtYale

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Sek Kathiresan MD @skathire

5 years ago

👇🏽one year ago today. Prescient

Joe Biden @JoeBiden

6 years ago

👇🏽one year ago today. Prescient

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Oded Rechavi @OdedRechavi

5 years ago

“This reviewer would like to see him use a stick”

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Mark Lewis, MD, FASCO @marklewismd

5 years ago

My patients with cancer shouldn’t be more afraid of losing their insurance than their life-threatening disease

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David R. Liu @davidrliu

5 years ago

A deep, informative analysis of #coronavirus airborne transmission risks that uses 5 documented #COVID19 "superspreader" events to estimate transmission parameters, then models infection risk of indoor dining, office mtg, class, taxi, shopping, flying. 1/2 medrxiv.org/content/10.110…

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Sam Rodriques @SGRodriques

5 years ago

New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstrating how we can encode the age of an RNA into its sequence to achieve "temporal transcriptomics" nature.com/articles/s4158…

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Jennifer Haythe MD @DrJennHaythe

5 years ago

1918 pandemic advice .. simple, direct, still true 😷

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Fyodor Urnov @UrnovFyodor

5 years ago

... I think at least 10k of those came from the genome editing field. Or so it seems.

Quite Interesting @qikipedia

5 years ago

... I think at least 10k of those came from the genome editing field. Or so it seems.

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Oded Rechavi @OdedRechavi

5 years ago

Guessing the reviewers’ identity

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Miles of infinity between 0 and 1 @neurooruen

5 years ago

My pregnant physician wife and I are currently COVID positive. We are currently quarantining with our 2 yo daughter who is likely also positive based on symptoms. We have both been working in hospitals taking every precaution humanly possible, especially because of the pregnancy.

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Florian Krammer @florian_krammer

5 years ago

That's leadership. Anthony Fauci is a national treasure.

Adam Phillippy @aphillippy

5 years ago

That's leadership. Anthony Fauci is a national treasure.

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Screaming Pectoriloquy (𝕖𝕩𝕖𝕔𝕦𝕥𝕖𝕕) @Caulimovirus

5 years ago

Thinking about all the times I’ve been told not to let a patient’s insurance status influence my medical decision making, something that’s been on my mind after spending ~2 hours trying to figure out a safe insulin plan for a newly diagnosed diabetic without any insurance.

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Not so Exhausted Anymore, Ph.D. @PhdExhausted

5 years ago

Since @AcademicChatter tweeted about it today, here's my "normalize" tweet *Normalize saying, "I need more time"* In the long run pulling all-nighters won't get you far, a healthy lifestyle definitely will.