Tim Blower @BlowerLab
Senior Principal Investigator at New England Biolabs and Honorary Professor at Durham University. Views my own. He/him. blowerlab.com New England Biolabs, MA Joined September 2020-
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RptR is a new addition to the growing collection of phage defence-associated transcriptional regulators. Congrats to @YugengZ @TangLabOxford @_MarionSchuller @IvanAhelLab and thank you, it was a pleasure to help out the study! @NEBiolabs. academic.oup.com/nar/article/53…
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Latest BREX story from the lab - turns out there is a nuclease after all! Congrats to Jenny Readshaw and the whole team, including wonderful collabs Barry Stoddard, Brett Kaiser and @DarrenSmithdx. @NAR_Open @NEBiolabs @DurBiol academic.oup.com/nar/article/53…
Tim Blower retweeted
We are delighted to host Professor Tim Blower @BlowerLab as keynote speaker to our MID symposium @WarwickLifeSci Date: 20th of June Venue: GLT1 We invite MBio, PhD students and Postdocs to submit abstracts for posters and talks by 11th of June to @CRodriguesLab
Tim Blower retweeted
For those of you who approached me at @MicrobioSoc #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!
For those of you who approached me at @MicrobioSoc #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!
Super opportunity to join Giusy in Glasgow!
Super opportunity to join Giusy in Glasgow!
Tim Blower retweeted
The final version of our Serratia paper is now out! Congrats to @TomCX99 and (X-less) Suraj, and a big thank you to @BlowerLab and @StephenRG97. tinyurl.com/3vnyvufa
The final version of our Serratia paper is now out! Congrats to @TomCX99 and (X-less) Suraj, and a big thank you to @BlowerLab and @StephenRG97. tinyurl.com/3vnyvufa
Tim Blower retweeted
Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the University of Glasgow @UofGSii ! 🎉 Can’t wait to get started on this exciting new chapter. Stay tuned—I’ll soon be advertising a PDRA position!
Tim Blower retweeted
Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date). @JohnInnesCentre @DurhamU34989 @MCB_UJ
Tim Blower retweeted
Thrilled to share my latest postdoc paper published in @NatureComms NTase toxin targeting serine tRNA 3'-ends by CMP addition in M. tuberculosis H37Rv. Thanks to all the co-authors, @GenevauxPierre @BlowerLab @ONeyrolles rdcu.be/dZle4
Tim Blower retweeted
When experiments don’t work... build a phage costume! 🎃 Happy PHAGEOWEEN!!! 👻🧬#Teamwork
Tim Blower retweeted
journals.asm.org/doi/10.1128/jv… Our thoughts on how toxins bound to TAs are activated: via conformation changes, not by selective degradation of ATs by a protease (makes little sense since both are structured). Remarkable insights determined by studying various TAs as they inhibit phage.
Tim Blower retweeted
Researchers @BlowerLab and colleagues use biochemistry, biophysics, and crystallography to characterize a mechanism of antitoxin induced autophosphorylation that can neutralize nucleotidyltransferase toxins of Mycobacterium tuberculosis nature.com/articles/s4146…
Tim Blower retweeted
Congratulations to @BlowerLab and @tomarrow234 Happy to be involved in this wonderful collaboration! NTase toxins are truly amazing! Dissecting the antitoxin-mediated Toxin auto-phosphorylation rdcu.be/dSXxi
Tim Blower retweeted
My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/
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