ISARIC4C @CCPUKstudy
The ISARIC Coronovirus Clinical Characterisation Consortium is recruiting COVID-19 patients. Urgent public health research supported by @NIHRresearch @HPRUezi isaric4c.net Joined February 2020-
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The results of the BESS trial will be announced at 14:40GMT today at the European Society of Paediatric and Neonatal Intensive Care, Alicante, Spain.
Timely collation, linkage and analysis of data has been key to informing the public health and clinical response in outbreaks of MERS, COVID-19, and Childhood Acute Severe Hepatitis of Unknown Origin @CCPUKstudy @ISARIC1 #DataSavesLives
Timely collation, linkage and analysis of data has been key to informing the public health and clinical response in outbreaks of MERS, COVID-19, and Childhood Acute Severe Hepatitis of Unknown Origin @CCPUKstudy @ISARIC1 #DataSavesLives
I have laid out how sharing data improves direct patient care, NHS effectiveness and supports medical research gov.uk/government/spe… The Information Commissioner, National Data Guardian and I have explained the benefits of clinical staff sharing data to support patient care.
I have laid out how sharing data improves direct patient care, NHS effectiveness and supports medical research gov.uk/government/spe… The Information Commissioner, National Data Guardian and I have explained the benefits of clinical staff sharing data to support patient care.
In general, the impact of Covid-19 on causing critical illness, i.e needing intensive care, in children lessened over the first two years of the pandemic, including when the omicron variant became dominant @CCPUKstudy @ISARIC1
In general, the impact of Covid-19 on causing critical illness, i.e needing intensive care, in children lessened over the first two years of the pandemic, including when the omicron variant became dominant @CCPUKstudy @ISARIC1
@EckerleIsabella @edwardcholmes Yes, along with loss of biodiversity, changing habitats of animals, illegal wild life trade, urbanisation, trade and travel. All key drivers more frequent & complex epidemics & pandemics. The epidemic events are symptoms of our changing world & need to address the key drivers
TL;DR: Our preprint was 1ST to report association btwn #AAV2 & hepatitis cases, found on metagenomic sequencing in 9/9 early 🏴cases vs 0/58 controls. #adenovirus found in 6/9 cases. Cases also >likely to carry HLA DRB1*04:01 allele (8/9; 89%) vs 🏴blood donors (16%) 2/
Doctors, scientists, & public health teams are working together, learning lessons from their responses to past outbreaks pandemics. This new way of working has led to the rapid discovery of the cause of this mystery disease @ISARIC1 @kennethbaillie @ProfCalumSemple
Doctors, scientists, & public health teams are working together, learning lessons from their responses to past outbreaks pandemics. This new way of working has led to the rapid discovery of the cause of this mystery disease @ISARIC1 @kennethbaillie @ProfCalumSemple
U.S. FDA Advisory Committee (VRBPAC) voted support the safety and effectiveness of GSK AREXVY™ (RSVPreF3 OA), 12-0 on effectiveness and 10-2 on safety. precisionvaccinations.com/rsv-vaccine-vo…
Cases (n=9): - admitted 14 March-4 April 22 - recruited to @CCPUKstudy - 4 male; median age 3.9 (IQR 3.4-5.1) - most had GI symptoms 1-11 wks b4 hepatitis - no immunocompromise - none had covid 💉 - Hep A-E, EBV/CMV, HHV6/7, HSV, autoantibodies neg - no transplants/ deaths 2/
@ISARIC1 @CCPUKstudy publication on our data platform. Thank you all partners & members for your contributions. rdcu.be/cSWBU
Comment piece from David Ulaeto, Miles Carroll & me: Evolutionary implications of human transmission of monkeypox: the importance of sequencing multiple lesions thelancet.com/journals/lanmi… We need multiple lesion samples & sequencing now to prove this @ISARIC1 @CCPUKstudy
Timely release of our latest @CCPUKstudy study, led by @LanceTurtle, evaluating impact of #immunocompromise (IC) on outcome in hospitalised #COVID19. TL;DR: Despite effective 💉& Rx, IC individuals remain at ⬆️ risk of death from COVID19 compared to immunoconpetent persons.
Timely release of our latest @CCPUKstudy study, led by @LanceTurtle, evaluating impact of #immunocompromise (IC) on outcome in hospitalised #COVID19. TL;DR: Despite effective 💉& Rx, IC individuals remain at ⬆️ risk of death from COVID19 compared to immunoconpetent persons.
🚨New preprint🚨 Adeno-associated virus 2 infection in children with non A-E #Hepatitis A case-control investigation of 9 early cases in #Scotland & 58 controls. @CVRinfo @P_H_S_Official @RHCGlasgow @CCPUKstudy @ucl @UKHSA @emcat1 🧵1/ medrxiv.org/content/10.110…
Great result and further evidence of the value of preparedness studies set up in readiness for future outbreaks of novel disease @gail_carson (the original CI), @ProfCalumSemple (CI & coLead) @kennethbaillie (coLead), @p_openshaw (coLead), @OutbreakJake & many more
Great result and further evidence of the value of preparedness studies set up in readiness for future outbreaks of novel disease @gail_carson (the original CI), @ProfCalumSemple (CI & coLead) @kennethbaillie (coLead), @p_openshaw (coLead), @OutbreakJake & many more
Brilliant News Jo and Team. Thank you so much for your help with @CCPUKstudy @ISARIC1
Brilliant News Jo and Team. Thank you so much for your help with @CCPUKstudy @ISARIC1
Many many congratulations to @ShonaCMoore, winning the Outstanding Contribution During The Covid-19 Pandemic, Shona and the team in our outbreak laboratories delivered the @CCPUKstudy which saved lives and enabled discovery on #COVID19
For UK hospitals that are ISARIC4C sites or are treating monkeypox patients and want to offer participation in the UK version of the CCP, see the updated UK CRF at isaric4c.net/protocols/ @CCPUKstudy
For UK hospitals that are ISARIC4C sites or are treating monkeypox patients and want to offer participation in the UK version of the CCP, see the updated UK CRF at isaric4c.net/protocols/ @CCPUKstudy
From @CCPUKstudy
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Peter Openshaw @p_openshaw
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Professor Calum Sempl... @ProfCalumSemple
6K Followers 2K Following I work with interesting people to reduce the impact of Severe Infections and Outbreak of Public Health Interest @BESStudy @CCPUKstudy @ISARIC1.
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ISARIC4C @ISARIC4C
9 Followers 2 Following Please follow ISARIC Coronavirus Clinical Characterisation Protocol UK study @CCPUKstudy , and not this account. Wishing you well, Calum Semple @ProfCalumSemple
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Professor Calum Sempl... @ProfCalumSemple
6K Followers 2K Following I work with interesting people to reduce the impact of Severe Infections and Outbreak of Public Health Interest @BESStudy @CCPUKstudy @ISARIC1.
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