Clinical Pharmacology & Analytical Chemistry Lab @CPACLab
The CPAC Lab, led by Angela Kashuba, dean of @UNCPharmacy, supports the global #HIV research community through expertise in pharmacology Joined April 2020-
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🎉 Happy to share that Eli Rosen was awarded an R01! This collaboration with OHSU will benchmark PK for both long-acting and daily ARVs in rhesus macaques and examine how pre-treatment immunopathogenic damage affects ARV tissue penetration reporter.nih.gov/search/xxd0xcu… #HIVResearch
Our collaboration with University of Colorado compares direct vs. indirect DBS assays for HIV PrEP adherence. We offer guidance for clinical interpretation, including adjustments for sample degradation outside cold-chain. 🔗 doi.org/10.1093/jac/dk… #HIVPrevention #PrEP
Antiretrovirals don’t reach all genital tissues equally—some areas may be underprotected. New imaging from a collaboration with our laboratory reveals why this matters for prevention and cure. #HIVresearch #ARVs #HIVprevention …ncbi-nlm-nih-gov.libproxy.lib.unc.edu/40323085/
New guidelines from a collaboration with our laboratory improve how we read PrEP drug levels in blood spots—helping ensure people get the protection they need. #HIVprevention #PrEP #Adherence …ncbi-nlm-nih-gov.libproxy.lib.unc.edu/40536250/
The HIV PDR is revolutionizing how HIV drug data is shared—making decades of research searchable, standardized, and ready to power the next breakthroughs in treatment and prevention. #HIVresearch #DataSharing Check out our publication here 👉 doi-org.libproxy.lib.unc.edu/10.1002/cpt.36…
#CROI2025 was fantastic! We are incredibly proud of Mackenzie Cottrell and her well-received oral presentation, "Optimizing On-Demand Tenofovir Disoproxil Fumarate/Emtricitabine Dosing in Women for HIV Prevention", which is featured on NATAP! natap.org/2025/CROI/croi…
Check out our upcoming abstract presentation when you're at #ASCPT2025!! A Modeling Approach to Expedite the Development of a New Long-Acting Controlled-Release Multipurpose Formulation Containing Medroxyprogesterone Acetate
Already looking forward to next year's International Workshop on Clinical Pharmacology of HIV, Hepatitis, and Other Antiviral Drugs! Enduring materials from this year's conference available here: academicmedicaleducation.com/meeting/intern…
Excited to announce our work was nominated for the 2024 Charles C. Shepard Science Awards @cdc! ncbi.nlm.nih.gov/pmc/articles/P…
Three papers from our lab for your weekend read! 📚 pubmed.ncbi.nlm.nih.gov/38427361/ ncbi.nlm.nih.gov/pmc/articles/P… ncbi.nlm.nih.gov/pmc/articles/P…
We are so proud of Mackenzie Cottrell for her promotion to Associate Professor @UNCPharmacy!! Check out her published works here 👉ncbi.nlm.nih.gov/sites/myncbi/1…
Congratulations @AKashubaUNC for this well-deserved award!!
Congratulations @AKashubaUNC for this well-deserved award!!
Fun lab outing eating @merrittsgrill BLTs and playing #pickleball!
Check out Amanda Schauer & Yury Desyaterik at #ASMS2024! 💊A Novel Assay to Measure Intracellular Endogenous Nucleotides and Active Antiretroviral Nucleotide Metabolites in Cell Lysate by LC-MS/MS 📷Image Deconvolution Restores MSI Spatial Resolution Following Signal Averaging
Congratulations Mackenzie for this incredible accomplishment!!! 🌟🎉🤩
Congratulations Mackenzie for this incredible accomplishment!!! 🌟🎉🤩

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