Crys Conn @CSConn_PhD
Assistant Prof @PennMedicine #RNA translation in cancer bio. Advocate for Science, Research, Healthy living & Equality #STEM #FirstGen #Fluid They/them CSConnLab.com Philadelphia, PA Joined April 2011-
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Crys Conn retweeted
Proximity-specific ribosome profiling using LOV-BirA reveals two distinct strategies for mitochondrially-localized translation: one for long coding sequences and one for short. It was a pleasure to contribute to this beautiful work from Jonathan Weissman @JswLab and @JingchuanLuo…
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Crys Conn retweeted
This preprint from Helen Sakharova is one of the coolest things to come out of my lab: “Protein language models reveal evolutionary constraints on synonymous codon choice.” Codon choice is a big puzzle in genome information, and we have a new angle. biorxiv.org/content/10.110…
Crys Conn retweeted
New exciting work from Jae Ho Lee in our lab, in a fantastic collaboration with Alessandro Ori @AOri_lab and Alessandro Cellerino @Alessan82703458 on why and how the brain ages and becomes vulnerable to neurodegenerative diseases science.org/doi/10.1126/sc…
Crys Conn retweeted
(1/n) Excited to share our new preprint! We uncover that RNA actively promotes nucleation and function of pathogenic condensates, amplifying locus-specific oncogenic transcription and promoting tumorigenesis. #epigenetics #condensates #cancer #RNA biorxiv.org/content/10.110…
Crys Conn retweeted
Early methionine availability attenuates T cell exhaustion @NatImmunol nature.com/articles/s4159…
Crys Conn retweeted
Super excited to share our newest piece out today @NatureRevCancer linking age-induced metabolic reprogramming to cancer development. nature.com/articles/s4156…
Crys Conn retweeted
Remembering the remarkable Marie Skłodowska Curie - awarded the 1903 physics prize and 1911 chemistry prize - who passed away #OTD in 1934.
Crys Conn retweeted
Hello RNA World! Ever wonder what's "talking to" your favorite transcript, but were too scared to ask? In our review in @CellReports, @FKHM and I highlight new RNA-focused tools for discovering RNA interactions across organizational scales. Checkit! tinyurl.com/ydn6e3ac
Crys Conn retweeted
I am delighted to share our new study uncovering the role of innate immunity in regulating cell plasticity and reprograming of prostate tumor initiating cells published in @NatureCancer . Congrats @ChenJiang919 and @yura__song , the first authors, nature.com/articles/s4301…
Crys Conn retweeted
WE ARE HIRING: Postdoc Positions! Join us at UPenn in vibrant Philly, cutting-edge science, great city, amazing team. Please share and let's get in touch!
Fantastic lecture by, new to UPenn, faculty Dr. Booker. Welcome to Penn and thank you for openly hosting a wonderful lecture for all today!
Fantastic lecture by, new to UPenn, faculty Dr. Booker. Welcome to Penn and thank you for openly hosting a wonderful lecture for all today! https://t.co/lVke3pwpPk
Crys Conn retweeted
Control of epithelial tissue organization by mRNA localization: nature.com/articles/s4146…
Crys Conn retweeted
Second paper on HMGA2 mediated basal identity in #PancreaticCancer from Sita Kugel @fredhutch. This one is an elegant mechanistic dissection of the multi step cascade through which HMGA2 overexpression orchestrates basal lineage state: nature.com/articles/s4146…
Second paper on HMGA2 mediated basal identity in #PancreaticCancer from Sita Kugel @fredhutch. This one is an elegant mechanistic dissection of the multi step cascade through which HMGA2 overexpression orchestrates basal lineage state: nature.com/articles/s4146… https://t.co/8FOdZvKgPV
Crys Conn retweeted
WE ARE HIRING (Postdoc Position)! Please share this with anyone who might be interested. Philly and UPENN are waiting for you!
Crys Conn retweeted
Really excited to see this published! From observations we made in our lab… to a blood test that works in real life scenarios… all thanks to the many scientists, ML researchers and engineers at @exaibio who have worked on bringing this to the clinic. Kudos Babak and the team!
Really excited to see this published! From observations we made in our lab… to a blood test that works in real life scenarios… all thanks to the many scientists, ML researchers and engineers at @exaibio who have worked on bringing this to the clinic. Kudos Babak and the team!
Cool new work explaining the dynamics of mRNA translation with the ribosome to inhibit SG localization- by the Moon Lab @smslmoon #ribosomes #uORF #mRNATranslation #StressResponse genesdev.cshlp.org/content/early/…
Crys Conn retweeted
Quality over quantity: Small RNA pauses translation elongation to lift protein activity dlvr.it/TKZLgx
Crys Conn retweeted
Check out our latest preprint, led by @schen_sc, that brings together an amazing team of scientists from several labs to tackle a fundamental problem in biology: how do cells regulate expression of their tRNAs? biorxiv.org/content/10.110…
Crys Conn retweeted
Beyond grateful to share that my main PhD thesis project, Targeting PIKfyve-driven lipid metabolism in pancreatic cancer (@LyssiotisLab @ArulChinnaiyan), has just been published in @Nature! @UMRogelCancer @UMICHpancreas @UMichMedSchool @UMichPath @UMichResearch @UMichCMB
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