CSHL Press publishes celebrated books, journals and other media in the fields of genetics, cell and molecular biology.cshlpress.org Cold Spring Harbor, NYJoined May 2010
The new issue of @genomeresearch is now live. Follow the link to new research on HER2 isoform diversity and drug resistance in breast cancer, off-target site detection in prime editing, and more! tinyurl.com/Genome-Res-35-9
The new issue of @genomeresearch is now live. Follow the link to new research on oxygen stress and gene regulation in the brain, a new C. elegans reference genome, and more! tinyurl.com/Genome-Res-35-8
NEW ISSUE ALERT!!!
Inspired by the 2025 CSHL Symposium on Aging & Senescence, this issue features a collection of Outlook, Perspective, and Review articles on the impact of aging on metabolism, immunity, reproductive health & cancer.
Online now:
➡️ genesdev.cshlp.org/content/39/15-…
The new issue of @genomeresearch is now live. Follow the link to new research on single-cell multiomics of muscle response to endurance exercise, a method for Nanopore data compression, and more! tinyurl.com/Genome-Res-35-7
The new issue of @genomeresearch is now live. Follow the link to new research on TP53 regulation of transposable elements in cancer, gut microbiome–associated protists, and more! tinyurl.com/Genome-Res-35-6
The new issue of @genomeresearch is now live! Follow the link to a new ultra-long nanopore sequencing toolkit, a unified analysis of atlas single-cell data, and more! tinyurl.com/Genome-Res-35-5
NEW ISSUE ALERT!!!
Check out the new Research Papers, Review, Perspective and Outlook Articles online now at Genes & Development.
Click on the link for more:
➡️ genesdev.cshlp.org/content/current
📽️ G&D Tapes 📽️
G&D author, Jelani Lyda talks about a new study in #GenesDev by Riley et al. reporting the role of ClpCP protease and novel protein MdfA in driving metabolic differentiation and dormancy during bacterial sporulation.
Learn more here:
➡️ tinyurl.com/gd352535
SF3B1: from core splicing factor to oncogenic driver.
This article from the #RNASpecialIssue discusses how specific transcripts affected by aberrant splicing in SF3B1-mutant cells contribute to the initiation and progression of cancer. It also highlights the prognostic value and…
RNA-binding proteins at the crossroads of disease: Fragile X Syndrome and Spinal Muscular Atrophy.
Discoveries of the SMN complex and its unanticipated function in RNP assembly, essential for spliceosomal snRNP biogenesis, advanced understanding of RNA biology and pathogenesis.…
SPECIAL ISSUE Part 2! This month @genomeresearch publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches. tinyurl.com/Genome-Res-35-4
Connecting genotype and phenotype in minor spliceosome diseases. This article from the #RNASpecialIssue outlines the current structural and functional knowledge of the minor spliceosome, and discusses emerging challenges in connecting molecular dysfunctions to clinical…
Our review epub @CSHLPress. Great ride led by Luis Batista @WashUHematology & by @CeiFccc@FoxChaseCancer contributing to an understanding of telomerase RNP - the immortality enzyme hijacked by 85% cancers and the untapped "fountain of youth" for aging diseases.…
This Perspective from the #RNASpecialIssue summarizes the current knowledge of translation dysregulation in cancer, with emphasis on the eukaryotic translation initiation factor 4F complex. It outlines recent endeavors to develop novel treatment strategies to combat cancer:…
Adenosine-to-inosine RNA editing by ADARs, first discovered in the 1980s, plays a complex role in disease. This #RNASpecialIssue review explores current knowledge, therapeutic potential, and key unanswered questions. bit.ly/3F3Vqy1
Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay.
This paper from the #RNASpecialIssue explores promising approaches employed to regulate NMD for therapeutic purposes, and highlights potential challenges in future clinical development.…
Cytoplasmic regulation of the poly(A) tail length as a potential therapeutic target: This review from the #RNASpecialIssue discusses the distribution, regulation, and mechanisms of cytoplasmic polyadenylation element-binding proteins (CPEBs), highlighting their dual roles in…
🧬 This National Children's Book Day, meet the tiny heroes inside us all!
Stem Cells to the Rescue from @CSHLPress is a rhyming science adventure that shows kids how our bodies heal. A fun, fact-filled read for classrooms, curious minds & future scientists!
#ChildrensBookDay…
Alternative splicing (AS) is crucial for heart function, and its disruption is linked to cardiac disease. While research focuses on gene missplicing, this article from the #RNASpecialIssue highlights nonsplicing roles of AS factors. The authors propose a novel disease mechanism…
17K Followers 2K FollowingAssistant prof at @StanfordMed. Interested in aneuploidy, mitotic kinases, cancer therapeutics, and drug development. Co-founder x2.
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