Cara Adolph @CaraAdolph
Research Fellow @Otago 🇳🇿 Tuberculosis research 🧪🧫 Dunedin, New Zealand Joined June 2021-
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Following131
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A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis by @CaraAdolph, Chen-Yi Cheung, Gregory M. Cook et al at @otago @microtago @MWC_CoRE dlvr.it/T5kYF4
Our latest work reporting that antibiotic resistance produces collateral drug phenotypes in Mtb is now published online in @NatureComms nature.com/articles/s4146…
In @Nature today (open access), we report the structural and mechanistic basis of how bacteria harvest energy from air. We reveal a novel enzyme, Huc, consumes atmospheric levels of hydrogen gas and transfers the derived electrons for aerobic respiration. nature.com/articles/s4158…
New preprint investigating drug-resistance in M. tuberculosis. Fantastic effort from PhD candidate Natalie Waller and all involved. biorxiv.org/content/10.110…
Excited to share the first paper from my PhD work out now in @mbiojournal 🎉 Here, we characterise the role of succinate dehydrogenase in the physiology and drug susceptibility of M.#tuberculosis. Thanks to my supervisors @cooklabuoonz & @mattmcneil86 doi.org/10.1128/mbio.0…
Derivatives of FDA-approved amiloride eliminate drug-resistant M. tuberculosis in vitro by interfering with bacterial energy conservation: nature.com/articles/s4200… @cooklabuoonz
New vacancy for an ARF position to work on mycobacterial genetics (below). otago.taleo.net/careersection/…

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