Cell Guidance Systems @CellGuidance
A biotechnology company focussed on protein formulation, self-assembling protein hydrogels, exosomes and cytogenetics. cellgs.com Cambridge, UK Joined September 2020-
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We have some exciting news for researchers working with mouse EVs! We've expanded our exosome product portfolio with mouse-validated solutions, bringing the same reliability you trust from CellGS to mouse research. Read more at lnkd.in/eTBZXEPp
Could Natural Killer (NK) cell-derived extracellular vesicles (EVs) revolutionise how we fight cancer? Recent NK-EV studies show promising anti-tumour activity across breast, colon, ovarian, and brain cancers. Read the article lnkd.in/eNdDNEXC #Cancer #exosomes
Do exosomes work as cosmetic ingredients? Cosmetics containing exosomes are now widely available. In our blog, we look at the rapidly growing exosome cosmetics market and explore the evidence for their cosmetic effect. Read here: lnkd.in/eDz-QtvF #comsetics #Exosomes
🧬 What are SASP “biological-clock” proteins and why do they matter? SASP proteins, which are secreted by senescent cells and act as biological timekeepers within the body. 👉 Read the article lnkd.in/eEb5BryY #BiologicalClock #Senescence #Biomarkers #Longevity
🚀 A Simpler Way to Model Biological Gradients Modeling gradients in vitro has always been a challenge with complex setups, limited reproducibility, and time-consuming methods. But what if there was an easier way? cellgs.com/blog/an-easier…
🔬💡There's gold in them there proteins! Can the reductive power of proteins purify gold from waste and seawater? 👉 Read the story here: lnkd.in/eBNn44ue #Biotech #MaterialsScience #PODS #UrbanMining #Nanotechnology #ProteinEngineering #GoldRecovery #CircularEconomy
🚀 Next-Gen Organoids Meet PODS® Smart Growth Factor Delivery 🧬 ✅ Long-lasting growth factor signalling ✅ Enhanced survival under stress ✅ Stronger expression of stemness markers (Nestin, CD166) ✅ Superior response to injury cues 🔗 lnkd.in/eSyXX9CA
Generating EV microRNA sequence data can be a technically challenging process. However, with the right workflow, backed up by easy-to-use kits from Cell Guidance Systems and Revvity, it becomes routine. Read more at: lnkd.in/e3WXk9b3 #microRNA #extracellularvesicles
CAR-T in solid cancer? With over 170 companies undertaking almost 2000 projects, CAR-T research is booming. But a myriad of challenges face CAR-Ts in solid cancers. Can they work? Find out more in our weekly blog. lnkd.in/ejj7JCxX #CAR-T
PROTACs: Degrading can be good Our informative weekly blog explores a technology that is bringing more drug targets into sight lnkd.in/eA8XKAv9
Double minutes are tiny chromosome-like structures associated with cancer that can generate uncontrolled increases in oncogene copy numbers. Read more in our weekly blog lnkd.in/eksWyDWe
Dependencies can be vulnerabilities. Does cancer's dependency on macrophages create a vulnerability? cellgs.com/blog/macrophag…
Using Softwell, a recent study has highlighted the importance of matrix elasticity in prostate cancer. Read more in our weekly blog. cellgs.com/blog/hard-luck…
Building better bone marrow models A recent study from Glasgow University describes a bone marrow model that may help to design improved CAR-T cells and guide target selection. Read more in our weekly blog lnkd.in/eFN-b22p
How diet and the gut microbiome influence prostate cancer progression The benefits of a good gut microbiome go beyond the gut and can impact the course of diseases, such as prostate cancer, in other organs. Read more in our weekly blog. lnkd.in/eFzTjSkM
Parkinson's cell therapy survival agent Recent reports of iPSC-based cell therapy for Parkinson's disease may indicate a therapeutic breakthrough. Second-generation cell therapies may benefit from cell survival agents to support implanted cells. lnkd.in/eahFRXbk
The central role of TAMs in cancer Tumour-associated macrophages (TAMs) play a key role in the genesis and aetiology of cancer. Unsurprisingly, TAMs are also in the crosshairs of experimental and approved cancer therapies. lnkd.in/e4b6XecK
Better Nerves for regenerative medicine Nerve conduits improve the growth of nerves across injured tissue. Using sustained-release nerve growth factor PODS improves their performance. cellgs.com/blog/sustained…
Immune cell boot camps in tumours may explain the abscopal effect Read more in our weekly blog lnkd.in/eM7_ibxd
A better understanding of immune evasion is leading to promising new therapeutic strategies. A recent paper highlights the importance of reactive oxygen species, mitochondria and IL-10 secretion from macrophages in generating immune evasion. lnkd.in/eSCUBPK4

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