Cosentino Lab - Molecular Cell Biophysics @Cosentino_Lab
Research group led by Katia Cosentino at CellNanOS, University of Osnabrück Joined February 2022-
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Following68
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Here comes our @NatImmunol N&V on a recent @Nature paper by the Chi lab @StJude on #mitochondria in the regulation of #IFN signaling in #cancer. Kudos to Katia Cosentino and Joost Verduijn! @RicercaUnimore @FoxChaseCancer Available at rdcu.be/emD1n
So excited that it's finally out! Congrats 🎉🎉 @EleMargheritis for your great work and all our fantastic collaborators!!! Gasdermin D cysteine residues synergistically control its palmitoylation-mediated membrane targeting and assembly | The EMBO Journal embopress.org/doi/full/10.10…
First visualization of super-resolved GSDMD pores at the plasma membrane of pyroptotic cells!!! Fantastic work by Shirin @viten_skap and great collaboration with @PiehlerLab iBiOs Osnabrück and @HummerLab Check our preprint! biorxiv.org/content/10.110…
I am amazed by the number of Italians I encountered at #EBSA2023 who are now living abroad. I have a mix of emotions here. I am sad that my homeland is emptying of outstanding scientists, but I am also proud of their courage in pursuing their dreams and embracing new journeys.
Looking for a great conference to end up 2023? Check out our Innate Sensing and Signalling in Immunology meeting (14-15 December 2023, Boston, USA) abcam.com/events/innate-… Organised by myself, @ClareBryant13 , @JelenaLab , @Rebecca_Coll and @abcam !
Structural basis of NINJ1-mediated plasma membrane rupture in cell death | Nature nature.com/articles/s4158…
This is pretty incredible. Now, there is a druggable target to delay cell death -or at least, membrane rupture. Potentially useful in settings in which caspase inhibitors did not work, from hepatitis (this paper) to stroke 👏@dixitvishva and team nature.com/articles/s4158…
Our RTG "nanomaterials@biomembranes" made it into the "final 11" - many thanks to the terrific team!
Our RTG "nanomaterials@biomembranes" made it into the "final 11" - many thanks to the terrific team!
Great team work @barisch_c and @HolthuisL !!!
Great team work @barisch_c and @HolthuisL !!!
Interested to work with a crowd of crazy scientists and support us in admin matters? We hire at the Biocenter, Medical University of Innsbruck. Full time. MS Office, English & German language required. @CeMM_News, @imed_tweets [email protected] for more info, please RT
Tremendous success: Biologists from Osnabrück University achieve funding by @dfg_public for Collaborative Research Center "Functional Plasticity Encoded by Cellular Membrane Networks". "We're delighted," said President Menzel-Riedl & Minister @FalkoMohrs. vt.uos.de/9zgnp
So honored and humbled to be selected as one of the recipients of the 2022 William B Coley Award, with Judy Lieberman, Feng Shao and Vishva Dixit (@dixitvishva) for our work on the pore forming proteins gasdermins, cancerresearch.org/news/2022/2022…
Congrats @viten_skap Shirin!!! for winning the poster prize at the #DGfB #biophysics2022 meeting in Konstanz!!!🎉🎉
The case for brakes: Why restrain the size of Bax and Bak pores in outer mitochondrial membranes?: Molecular Cell cell.com/molecular-cell…
On #IWD2022, a huge shout out to all those fabulously talented #WomenInSTEM out there, including (but not limited to) all the exceptional female trainees, colleagues, collaborators and supervisors I have worked with over the years! 🎉
The pyroptosis executioner gasdermin D (GSDMD) is a redox sensor. Our new study demonstrates that GSDMD is oxidized to potentiate its oligomerization and pore forming activities, with Cys192 playing a critical role in ROS responsiveness. biorxiv.org/content/10.110…
Happy to announce that @BBAjournals have made the collection of articles on "Death Mechanisms in Cellular Homeostasis" freely accessible for the next 2 months! Feel free to explore and to RT to your network: sciencedirect.com/journal/biochi… @EuroCalcium @Eric_Chevet @crismunozp @MitosRUs
BAX and BAK apoptotic pores are different! They release mitochondrial DNA at different speed ⚡️⚡️⚡️ Check out our latest paper in Molecular Cell authors.elsevier.com/sd/article/S10…

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