Deep mutational scanning @DeepScanning
Curated posts on deep mutational scanning Joined May 2020-
Tweets30
-
Followers60
-
Following59
-
Likes2
Inferring protein sequence-function relationships with large-scale positive-unlabeled learning biorxiv.org/content/10.110…
0
0
0
0
0
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals... sciencedirect.com/science/articl… @tylernstarr
A Method for User-defined Mutagenesis by Integrating Oligo ... bio-protocol.org/e3697#.XzA85vb…
Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR tandfonline.com/doi/full/10.10…
Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2 science.sciencemag.org/content/early/…
Mapping the Functional Landscape of the Receptor Binding Domain of T7 Bacteriophage by Deep Mutational Scanning biorxiv.org/content/10.110…
Altered expression of a quality control protease in E. coli reshapes the in vivo mutational landscape of a model enzyme doi.org/10.7554/eLife.…
The adaptive potential of the middle domain of yeast Hsp90 biorxiv.org/content/10.110…
DropSynth 2.0: high-fidelity multiplexed gene synthesis in emulsions academic.oup.com/nar/article/do…
Diversification of DNA-Binding Specificity by Permissive and Specificity-Switching Mutations in the ParB/Noc Protein Family cell.com/cell-reports/f…
Using deep mutational scanning to benchmark variant effect predictors and identify disease mutations | Molecular Systems Biology embopress.org/doi/full/10.15…
MAVE-NN: Quantitative Modeling of Genotype-Phenotype Maps as Information Bottlenecks biorxiv.org/content/10.110…
A genotype-phenotype-fitness map reveals local modularity and global pleiotropy of adaptation biorxiv.org/content/10.110…
Protein tolerance to random circular permutation correlates with thermostability and local energetics of residue-residue contacts academic.oup.com/peds/article/d…
Using deep mutational scanning to benchmark variant effect predictors and identify disease mutations | Molecular Systems Biology embopress.org/doi/10.15252/m…
Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides pnas.org/content/117/26…
A survey of pairwise epistasis supports an outside-in hierarchy of clade-specifying and function-defining residues in PSD95 PDZ3 biorxiv.org/content/10.110…
Deep mutational scanning retweeted
I teach a structural biology/protein science/biophysics course and it’s fun that we can now include deep mutational scanning as one of the techniques for providing insight into protein stability and structure. Here are some examples I used today: 1/
Balance between promiscuity and specificity in phage λ host range biorxiv.org/content/10.110…
DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies biorxiv.org/content/10.110…
Oana Antonescu @antonescuoana
326 Followers 462 Following protein nerd | scientist @ExpreS2ionB | postdoc in structural biology from @cancer_dk | PhD from #LinderstrømLang @koebenhavns_uni | MPharm
Janine Copp @jn_copp
155 Followers 309 Following antibodies | enzymes | protein engineering | sciencemom | Kiwi | Canadian
Noel Unciano @ntwit_nmu
9 Followers 80 Following
Kotryna Kauneckaitė-... @griguole
12 Followers 165 Following
Mehdi D Davari @mehdi_d_davari
128 Followers 285 Following Group leader at the Leibniz Institute of Plant Biochemistry (IPB)
Umut. Dişel @UmutDisel
1K Followers 5K Following Tıbbi Onkoloji Uzmanı, Medical Oncologist MD, Acibadem Hospital Adana, Turkey. Nextgene Oncogenomics Solutions
Kathleen Sprouffske @ksprouffske
93 Followers 146 Following Data scientist. Cancer epi/genomics, evolution, models.
Christine Mordstein @CMordstein
709 Followers 1K Following RNA Therapeutics | Gene expression regulation RNA by Design Leader @ Centillion | Views my own. ***Find me where the sky is blue ➡️ @cmordstein.bsky.social
David Schnettler @JDSchnettlerF
89 Followers 160 Following Inactive. Find me on Bluesky or Mastodon https://t.co/986si2erZ8 https://t.co/OEJin8eGdc
Center for the Multip... @CEGS_CMAP
479 Followers 86 Following We are a Center of Excellence in Genome Sciences, developing technologies to assess the functional impact of variants in human genes.
Dvir Schirman @DvirSchirman
260 Followers 586 Following @EMBOFellows postdoc in @johan_elf_ lab, @UU_University. Chromosome organization in bacteria, Single-molecule imaging, Systems biology. alumnus of @TPilpel lab
Jaeda Patton @jaedapatton
212 Followers 691 Following sequence space-head 🧬🌌 // PhD student with @JoeThorntonLab @UChicagoGGSB
Xiaohan Li @xlichem
505 Followers 1K Following Postdoc in Miller lab @UoDLifeSciences. Previous: #MSCAFellow @MRC_LMB; PhD @YaleChem; CCME @PKU1898 IDP/IDRs, membrane traffic, protein dynamics, evolution.
Jennifer Michaud @jmmichaud
4 Followers 22 Following
Michael A. Nash @nash_lab
728 Followers 668 Following Professor for Engineering Synthetic Systems - Univ. Basel & ETH Zurich (@UniBasel_en, @ETH_en); Bioengineering, Nanotechnology, Biophysics; Alumnus @UCLA @UW
Santiago Herrera Álv... @santiagoherrer_
1K Followers 2K Following Evolutionary genetics-biochemistry 🧬⛰️ @JoeThorntonLab | Trying to avoid fitness valleys | All things #molevol #popgen #evodevo #cienciacriolla 🇨🇴
José Aguilar-Rodríg... @jaguilarrod
1K Followers 3K Following Evolutionary cell biologist @Stanford. EMBO and SNSF Postdoctoral Fellow with @PetrovADmitri and @JaroszLab. PhD with @WagnerEvolution.
M. Madan Babu @m_madan_babu
2K Followers 2K Following Dept. of Structural Biology, St. Jude Children's Research Hospital Chair in Biological Data Science Director, Center for Data Driven Discovery @StJudeStructBio
Kritika Mehta @Kritika1794
128 Followers 280 Following Postdoctoral Associate @WeillCornell #neuronalMetabolism | PhD @Illinois_alma | Proud alum @iitbombay @univofdelhi | Reduce #CarbonFootprint | she/her
Taylor Mighell @taylor_mighell
240 Followers 700 Following EMBO Postdoc Fellow with @BenLehner at @CRGenomica. GPCRs, synthetic biology, genomics, machine learning, tech development. Alum @ngpohsu. He/him.
Sarah Gersing @s_gersing
66 Followers 121 Following PhD student at #LinderstrømLang Center for Protein Science, @BIO_UCPH
Coline @Coline_Sivelle
6 Followers 119 Following PhD in protein engineering/immunology Currently working on IgE mediated allergies at @AarhusUni
Guillaume Cambray @GiomCambray
193 Followers 133 Following High-throughput synbio (currently profiling viruses for biocontrol of insect pests)
Calin Plesa @calinplesa
1K Followers 2K Following Assistant Prof. @UOKnightCampus. Cofounder @SynPlexityDNA. Protein engineering, gene synthesis, synbio, nanopores, multiplex assays. Opinions my own.
gulliverbear @gulliverbear
38 Followers 131 Following
Jonathan Frazer @Jonnygfrazer
1K Followers 2K Following Probabilistic machine learning for diagnosis and preemptive care. #EvolutionaryMedicine. PI at the @CRGenomica.
Conor Camplisson @ConorCamplisson
118 Followers 560 Following Graduate Student with @oligopain at @uwgenome.
Josh Atkinson @meeeeechigan
1K Followers 3K Following Assistant Prof. in CEE & the @omenndarlingbio institute at @EPrinceton - find me over on bsky
Michael Dorrity @mwdorr
755 Followers 775 Following American biologist, fan of sound. | Group Leader @embl | fish, temperature, developmental timing
Zach Wu @ZvxyWu
1K Followers 592 Following RS at Google Deepmind, previously Arnold/DeLisa research groups at Caltech/Cornell.
Isaac Jia 贾小彦 @Jia_Xiaoyan
66 Followers 91 Following Research Postdoctoral Fellow @ University of Michigan
Alan Rubin @rubin_af
809 Followers 808 Following Trying to figure out what genomic variants do. Computational biologist at @WEHI_research. Previously @uwgenome. Mastodon: https://t.co/6EtfEJxhLP
Flo Chardon @FloChardon
525 Followers 260 Following Scientist and computational biology team lead at the Seattle Hub for Synthetic Biology at the Allen Institute. PhD with @JShendure and @lea_starita.
Kenneth Matreyek @kmatreyek
609 Followers 448 Following X is a broligarchy propaganda platform. This is no longer a professional account; I’ll only use it to yell at politicians not on Bluesky.
Lara Muffley @LaraMuffley
427 Followers 1K Following Director of Program Operations for CMAP, CAVA and the Atlas of Variant Effects Alliance | Fowler Lab @uwgenome | she/her 🏳️🌈
Andrew Glazer @amglazer
472 Followers 557 Following Assistant Professor at Vanderbilt Univ. Medical Center. Arrhythmia genetics, ion channels, high-throughput methods. https://t.co/SME2KRmfPt.
Vanessa Nguyen @vanesngu
20 Followers 73 Following
Wenjun Xie @EvoCatalysis
258 Followers 727 Following Assistant Professor @UFPharmacy, understanding how natural enzymes are evolved to design reaction-based drugs
Papaleo Labs @ElePapaleo
1K Followers 2K Following We are an enthusiastic group of researchers in cancer bioinformatics and cancer structural biology. Our homes are at DCRC and DTU Health Tech (DK)
Nicolas Jonsson @NicolasJonsson
137 Followers 264 Following PhD Student | Computational biology | Structural bioinformatics | Machine Learning @ the #LinderstrømLang Centre for Protein Science @uni_copenhagen 🇩🇰
Johanna Tiemann @j0kaso
797 Followers 649 Following Senior Data Scientist @Novonesis. She/her. LGBTQ+
Mohammed AlQuraishi @MoAlQuraishi
11K Followers 350 Following MLing biomolecules en route to structural systems biology. Asst Prof of Systems Biology and CS @Columbia. Prev. @Harvard SysBio; @Stanford Genetics, Stats.
Kritika Mehta @Kritika1794
128 Followers 280 Following Postdoctoral Associate @WeillCornell #neuronalMetabolism | PhD @Illinois_alma | Proud alum @iitbombay @univofdelhi | Reduce #CarbonFootprint | she/her
Pawan Kumar @pawanomar29
30 Followers 274 Following Enthusiastic Learner and Cheminformatician by profession. Opinion matters and it is mine.
xavier salvatella @xsalvatella1
1K Followers 1K Following Scientist at @icreacommunity and @irbbarcelona, working in biophysics. I like mechanisms, driving forces, conformations, non-covalent interactions.
clara rehmann @ramencult
16K Followers 820 Following raising a bearded dragon, writing in Python, getting a PhD. Kern Ralph co-lab @ UofO ( she/her 🏳️🌈 )
Jonathan Mosley @JDMosley_Moses
411 Followers 408 Following Physician Scientist interested in how genetics impact health and disease. Opinions my own (and the puppet master).
Guillaume Cambray @GiomCambray
193 Followers 133 Following High-throughput synbio (currently profiling viruses for biocontrol of insect pests)
Junyue @junyue_cao
2K Followers 345 Following
John Karanicolas (he/... @JohnKaranicolas
732 Followers 518 Following Advancing scientific knowledge to benefit human health. Head of computational drug discovery at AbbVie.
The Vilcek Foundation @Vilcek
4K Followers 3K Following The Vilcek Foundation raises awareness of immigrant contributions in the United States and fosters appreciation of the arts, sciences, and humanities.
Kortemme Lab @KortemmeLab
1K Followers 48 Following Our lab @UCSF focuses on protein design to engineer advanced functions and understand cellular processes! Tweets by lab members unless signed with TK.
Colin Jackson @Jackson_Lab
2K Followers 1K Following Protein Engineering and Evolution. Views my own.
Calin Plesa @calinplesa
1K Followers 2K Following Assistant Prof. @UOKnightCampus. Cofounder @SynPlexityDNA. Protein engineering, gene synthesis, synbio, nanopores, multiplex assays. Opinions my own.
Pallav Kosuri @PallavKosuri
787 Followers 214 Following DNA origami, molecular motors and cardiac biology | Assistant Professor @salkinstitute | 🇸🇪
Jonathan Frazer @Jonnygfrazer
1K Followers 2K Following Probabilistic machine learning for diagnosis and preemptive care. #EvolutionaryMedicine. PI at the @CRGenomica.
Victor V. Lobanenkov @boris_ctcf
2K Followers 5K Following Verifiable facts and personal notes related to paralogous CTCF & CTCF Like BORIS factors which share eleven near-identical DNA\RNA\protein-binding Zn fingers
Liz Tseng @Magdoll
4K Followers 1K Following Applications product manager @PacBio. #RNA/#GeneTherapy/#bioinformatics. @uwcse PhD. she/her. Aerialist/pole dancer. Opinions are my own.
Bryson Lab @TheBrysonLab
4K Followers 2K Following Engineering innate immunity // Host-pathogen interactions // Systems Biology // Tuberculosis @MIT @MITDeptOfBE
Stephan Hacker (inact... @StephanHacker2
5K Followers 2K Following Inactive account. Find me at: @stephanhacker2.bsky.social @[email protected] https://t.co/kPr9QkAN2S
Josh Atkinson @meeeeechigan
1K Followers 3K Following Assistant Prof. in CEE & the @omenndarlingbio institute at @EPrinceton - find me over on bsky
Ben Livesey @BenLivesey6
41 Followers 7 Following Postdoctoral researcher at the Institute of Genetics and Molecular Medicine, Edinburgh. Likes proteins, cats.
Michael Eisen @mbeisen
73K Followers 13K Following I science & try to make science open. Tweets do not represent my employer's views, but are always correct. My conflicts of interest https://t.co/77P0LDdz6j.
Kenneth Matreyek @kmatreyek
609 Followers 448 Following X is a broligarchy propaganda platform. This is no longer a professional account; I’ll only use it to yell at politicians not on Bluesky.
Jay Shendure @JShendure
14K Followers 316 Following Genomics technology developer. Developmental biology adult learner. Professor at @uwgenome @HHMINEWS @BrotmanBaty. He/him.
Genomics Salon at UW @GenomicsSalon
191 Followers 11 Following A place for interdisciplinary discussion of science and society at University of Washington. https://t.co/fZT8qtGUGn
Andrew Glazer @amglazer
472 Followers 557 Following Assistant Professor at Vanderbilt Univ. Medical Center. Arrhythmia genetics, ion channels, high-throughput methods. https://t.co/SME2KRmfPt.
Dmitri Petrov @PetrovADmitri
14K Followers 4K Following Evolutionary Biologist at Stanford. Rapid Evolution, Adaptation, and Genomics. Open Science advocate.
KerryGeilerSamerotte @KSamerotte
1K Followers 544 Following Evolutionary cell biology. Epistasis. Pleiotropy. Yeast. Science outreach.
Brooke Angell @beangell95
32 Followers 67 Following @IBiSatNU grad student | former @UWgenome lab tech | @Middlebury class of 2018
Dr Gaetan Burgio @gae... @GaetanBurgio
11K Followers 1K Following Group leader, Australian National University ANU, Australia. Geneticist working on infections & #CRISPR. Opinions and views ....
Papaleo Labs @ElePapaleo
1K Followers 2K Following We are an enthusiastic group of researchers in cancer bioinformatics and cancer structural biology. Our homes are at DCRC and DTU Health Tech (DK)
Marqusee Lab @MarquseeLab
1K Followers 1K Following The Marqusee Lab @UCBerkeley uses #biophysics to study #proteinfolding in basic and cellular contexts. Account is student/postdoc run. All tweets in kcal/mol.
Nicolas Jonsson @NicolasJonsson
137 Followers 264 Following PhD Student | Computational biology | Structural bioinformatics | Machine Learning @ the #LinderstrømLang Centre for Protein Science @uni_copenhagen 🇩🇰
James Fraser (A$AP J) @fraser_lab
7K Followers 1K Following Professor and Chair @UCSF/@UCSF_BTS - dynamic structural biology and open science - (he/him)
Amelie Stein @_amelie_rocks
2K Followers 3K Following Assoc Prof @ U of Copenhagen. Better at plots than blots. ❤️ proteins, strong feelings about many others things, too. Trying to listen & learn. She/her.
Joseph Rogers @JosephRogers100
662 Followers 675 Following Cyclic peptide finder, protein folder, drug discoverer. Associate Prof. at University of Copenhagen.
Alex Nisthal @AlexNisthal
40 Followers 61 Following
Debora Marks @deboramarks
4K Followers 189 Following Mission: design of biological interventions for environment and human health (to save the world)
Ben Lehner @BenLehner
5K Followers 4K Following Head of Generative and Synthetic Genomics @sangerinstitute; Systems + Synthetic Biology @CRGenomica; Co-founder https://t.co/5N3PvqNXec https://t.co/l6NKYFgZBP
Kresten Lindorff-Lars... @LindorffLarsen
15K Followers 2K Following Protein and coffee lover, father of two, professor of biophysics and sudo scientist at the #LinderstrømLang Centre for Protein Science 🇩🇰
Cathy Smith @smithcat1661
98 Followers 216 Following Bioinformatistatistician PhD student @UMich studying genomics and free food.
Javon kate @javon_kate
1K Followers 4K Following Keep on swimming 💪 The principle of true art is not to portray but to evoke ✨🎨
Peter Kasson @peterka... @kassonlab
1K Followers 130 Following We study physical mechanism at the pathogen-host interface. Professional account @[email protected]
Alfonso Cortés Salga... @AlfonsoCorts9
782 Followers 831 Following Medical Oncologist | Breast & Gynaecological tumors | Ramón y Cajal University Hospital
mutational signatures... @mutSignatures
251 Followers 6 Following Twitterbot for tweets and #PubMed articles with keywords of mutational signatures and hashtags #MutationalSignature. Updated daily. Curated by @zhiiiyang.Trends for United States
24,9 B posts
6.072 posts
60,3 B posts
38 B posts
2.338 posts
11,4 B posts
17,5 B posts
3.474 posts
5.834 posts
23,1 B posts
22 B posts
6.268 posts
6.795 posts
5.477 posts
2.152 posts
16,8 B posts
3.464 posts
16,8 B posts
You might like
Kim Reynolds
@kimreynolds_lab
646 Followers
Benedetta Bolognesi
@Bennibolo
1K Followers
Max Frenkel, MD, PhD
@CasualVariant
301 Followers
Xianghua (Cici) Li
@XianghuaLi2
135 Followers
Moez Dawood
@MoezDawood
220 Followers