Discover the dynamic influx-efflux tug-of-war in live Gram-negative bacteria! @Manabendra_IITK group shows that E. coli's AcrAB-TolC tripartite RND efflux pump can still expel drugs even with one component missing, thanks to its bipartite resilience.
📑 go.acs.org/auV
Excited to share my contribution in the field of Multidrug resistance!! Here, We provide first evidence of efficiently working bipartite complexs of AcrAB-TolC efflux pump in living E.coli bacteria | The Journal of Physical Chemistry Letters pubs.acs.org/doi/10.1021/ac…
Discover how osmotic stress impacts drug permeation across the E. coli cell envelope! Fascinating research from @Manabendra_IITK group finds membrane permeability, not electrostatic screening, prevents QACs from entering the cells. @Deepak3a3@IITKanpurgo.acs.org/9zt
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