Matthew Cotant, MD @DocMCotant
Medical Oncologist, happily married to love of my life, 3 great kids, many dad jokes. Royal Oak, MI Joined December 2011-
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The need for pneumonectomy should not be considered a criterion for unresectability, and thus should not be used as a justification for CRT. In CheckMate 816, patients who underwent pneumonectomy had a 5-year OS of 80%!
The need for pneumonectomy should not be considered a criterion for unresectability, and thus should not be used as a justification for CRT. In CheckMate 816, patients who underwent pneumonectomy had a 5-year OS of 80%!
🆕🗞️Hot off the press! @NatureMedicine #KRAS Vaccine💉for patients with RAS➕cancers🎯. Benefit➡️durable.🙌🏽 More to come with the randomized study📚✔️! Opens to doors to off the shelf vaccine for so many patients with KRAS/NRAS mutations. @OncoAlert 🔗nature.com/articles/s4159…
EV303: EV-Pembro Significantly Improved Event-Free and Overall Survival and pCRs in cis-ineligible MIBC pts. A practice changing trial to be presented at #ESMO25 @OncoAlert @_SEOM @GuardConsortium @myESMO merck.com/news/keytruda-…
KEYNOTE905: #Pembrolizumab + #EnfortumabVedotin before & after cystectomy improved EFS, OS & pCR vs surgery alone. A new SOC may be on the horizon for this high-risk group can’t wait to see the full data! #BladderCancer #Oncology #Immunotherapy #ADCake @MattGalsky @AndreaNecchi…
I absolutely can’t wait to read this new memoir out from my friend Dr. Nasser Hanna @hannawants2ELCN , a #LungCancer med onc who has been an inspiration and role to me for 20 years. His wisdom is unparalleled. Check it out!! Congrats Nasser!!! @ASCO @tmprowell @chrisdraft
Implications of BRAF V600E in dMMR/MSI-H pts treated with ICIs. Prognostic impact of the BRAF V600E mutation in patients with MSI-high... sciencedirect.com/science/articl… @AACR @JCO_ASCO @ASCO @MayoCancerCare
‼️Press release: #FLAURA2 shows osimertinib + chemo improves OS in EGFR+ lung cancer — “statistically significant & clinically meaningful.” Combos may be in, but informed & shared decision-making stays key. Excited to review full data! @OncoAlert
‼️Press release: #FLAURA2 shows osimertinib + chemo improves OS in EGFR+ lung cancer — “statistically significant & clinically meaningful.” Combos may be in, but informed & shared decision-making stays key. Excited to review full data! @OncoAlert https://t.co/G8xIE9vo0E
Prospective study of stereotactic radiation for treatment of brain metastases (1-10) in SCLC (instead of whole brain radiation) @JCO_ASCO. In 100 pts (median number of metastases was 2), only 22% of pts required salvage WBRT, mOS 10.2m. ascopubs.org/doi/10.1200/JC…
🚨 #Lungcancer survival has more than doubled. New real-world data from France shows 3-year survival for lung adenocarcinoma rose from 16.3% (2000) to 38.6% (2020) driven by earlier diagnosis & targeted treatment. This is what progress looks like. But it must reach everyone who…
The NCCN has included adjuvant atezolizumab (for 1 year) in the treatment of stage pT2c–III dMMR colon cancer. Given the positive trial results, its inclusion is certainly appropriate. However, the guideline adopts a somewhat conservative stance regarding neoadjuvant ICI use,…
Please take a moment to read this blog on the recently activated NRG-GI011 trial in locally advanced #PancreaticCancer ! 👇
Please take a moment to read this blog on the recently activated NRG-GI011 trial in locally advanced #PancreaticCancer ! 👇
🚨 STELLAR-303 makes history! First-ever Ph3 trial to show OS benefit of IO in MSS CRC 🎯 Years of grit & belief led us here 🥹 Endless thanks to Exelixis for the trust & Dr. Hecht for leading this global win with me! 🎉 @UPMCHillmanCC ir.exelixis.com/news-releases/…
📘3 recent updates in NCCN guidelines based on recent studies/approvals ✅Advanced anal SCC, 1L Retifenlimab-carbo-pacli ✅Unres/met pheochromocytoma/paraganglioma Belzutifan ✅Cancer assos VTE Apixaban reduced to 2x2.5 mg after 6months #cancer #oncology #MedX @OncoAlert
These are important data and should change practice for LGL leukemia. @OncBrothers
These are important data and should change practice for LGL leukemia. @OncBrothers
What patients are eligible for adjuvant CDK4/6i? We looked at this in @ConcertAI: the approval of ribo doubled the pts eligible for adjuvant CDK4/6i (15%➡️30%) and provided an option for 10% of pts with N0 disease, those with the most aggressive cancers. esmoopen.com/article/S2059-…
Important to note that in the randomized trial showing equivalence of TCHP and THP that patients got 18 weeks of therapy with THP (not the more common 12 weeks) which might account for both higher pCR rates and lack of need for carboplatin.
Important to note that in the randomized trial showing equivalence of TCHP and THP that patients got 18 weeks of therapy with THP (not the more common 12 weeks) which might account for both higher pCR rates and lack of need for carboplatin.
NSABP B-51: RNI vs no RNI in ypN0 after neoadjuvant chemo (cT1-T3N1) 5y iBCRF➡️92.7% vs 91.8% 5y OS➡️93.6% vs 94.0% 💥No clear benefit from RNI in patients downstaged to ypN0 📌HR+/HER2– needs longer follow-up 📌TNBC may even fare worse with RNI nejm.org/doi/full/10.10…
#ASCO25 And another one! @JCO_ASCO: 5-yr CARTITUDE-1 results for cilta-cel CAR-T. 97 pts, 6 prior #MMsm lines, treated 2018-2019. All likely would have died; instead, 1/3 alive & well 5 yrs out with no maintenance! 👏 Beginning of the end for #plateauenvy? (cc @ninashah33)
#ASCO25 day 4: early LBA session in #BreastCancer A possible new SOC in the first-line setting for HER2+ MBC DESTINY-Breast09: - Median PFS was significantly improved with T-DXd+P vs THP (40.7 months vs 26.9 months) - Benefit consistent across subgroups - Median DOR > 3 years…
👉Results of IMforte trial of: 👉Lurbinectedin + Atezolizumab as 1st line #Maintenance Tx in Extensive stage small cell lung cancer 👉significant improvement in pfs hr 0.54 👉significant improvement in os hr 0.73 #ASCO25 #ASCO #OncoDaily #larvol #oncology @OncoAlert

Charlotte @kristallaloka
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Moh’d khushman @khushmanmd
603 Followers 545 Following Father, husband and associate professor/GI oncologist @ Wash U/SCC. Research interest #molecularprofiling #biomarker discovery #exosomes and #pharmacogenomics
Ron Levitin, MD @rlevitinMD
1K Followers 1K Following Board Certified Radiation Oncologist at the Beaumont Health Lenox Outpatient Center in Southeast Michigan views my own
م. عمر الدعج... @OmarMOAlDajani
59 Followers 137 Following إنسانٌ تستهويه البساطة؛ لا يزال قبطاناً في بحرِ الأفكار؛ لم تكتملْ أوراقه و لم تنفدْ محبرَته؛ يرى الساحل من بعيد، لكن طواقمه كُسالى.
Doctor Podcasts @DoctorPodcasts
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Mark Lewis, MD, FASCO @marklewismd
93K Followers 35K Following Director, GI Oncology, @Intermountain. Interests: neuroendocrine tumors, cancer syndromes, empathy (even had a Whipple myself). Tweets my own.
Hem-Onc Fellows Netwo... @HemOncFellows
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Eris Tollkuci, PharmD... @ErisTollkuci
82 Followers 186 Following Executive Medical Science Liaison @sanofius I Fmr Heme PharmD at @RushMedical + Ast Professor @RFUniversity I Fungi Enthusiast l Opinions are my own I #MMSM
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Plus Therapeutics (Na... @plustxinc
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Christine Lovly, MD, ... @christine_lovly
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Kohei shitara @KoheiShitara
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William Aird @WilliamAird4
30K Followers 320 Following Professor of Medicine at Harvard Medical School #Hematology #MedEd Founder of @TheBloodProjec1
LungCancerRx 🫁💊 @LungCancerRx
874 Followers 166 Following ✍️ Prescribing empowerment, knowledge & hope in #lungcancer | 🤝 Team @adesaimd @fawziaburous @lungoncdoc | 🫶 #lcsm #WCLC25
Together4Cancer @T4Cancer
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Ilana Schlam @IlanaSchlam
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118K Followers 2K Following 2X NL MVP, 7X MLB All Star, Motivational Speaker, owner of ‘Murph’s’ restaurant (Atl) proud father of 8, and proud grandfather of 20.
Sunnie Kim, MD @SunnieSKim
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1.1M Followers 1 Following Author of the #1 NYT bestseller Atomic Habits (https://t.co/aWrO9DWkH5). I write about building good habits. Over 3 million people read my 3-2-1 newsletter.
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Gʀᴇɢᴏʀʏ Rɪ�... @RielyMD
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630 Followers 230 Following
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Paolo Tarantino @PTarantinoMD
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Thread Reader App @threadreaderapp
786K Followers 1K Following I'm a 🤖 to help you read threads more easily. Reply to any tweet of a thread and mention me with the "unroll" keyword and I'll give you a link back 😀