Chromophobe #kidneycancer therapy remains elusive. Why? what is the underlying mysterious biology? What are the targets? is immunotherapy "a thing" in #Chromophobe RCC? Our review with @LisaHenske @LiangChengMD @arihakimi (@Yankees fan) & @BraunMDPhD is now published in @Cancer_Cell. Enjoy the read! sciencedirect.com/science/articl…
@DrChoueiri @LisaHenske @LiangChengMD @arihakimi @Yankees @BraunMDPhD @DanaFarber @DanaFarber_GU @Yale @YaleHemOnc @YaleCancer @BrighamWomens @kcCURE We reported in 2021 p21 & Rb truncating mutations in kidney chromophobe renal cell carcinomas with suspected implications for therapy & pathogenesis. I’m fascinated by p21 & Rb truncating mutations in bladder tumors as well. More research is needed. ncbi.nlm.nih.gov/pmc/articles/P…