Metallobiochemistry lab at UTSA @FeRadLab
Dr. Aimin Liu's MetalloBioChemistry Lab at the University of Texas at San Antonio (student run). Joined July 2020-
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The Welch-funded project at @UTSAChemistry, led by PI Aimin Liu (@Dr_Feradical), has resulted in a new publication in the high-profile chemistry journal Angewandte Chemie. This work uncovers how the iron-containing oxindole-installation enzyme MarE shifts gears in oxygenation…
New publication alert! Check out our findings on MarE chemistry and how our engineered loop-swapping between MarE (SLGGR) and TDO (GTGGS) showed the importance of its role in directing oxygenation outcomes! @angew_chem @UTSAChemistry doi.org/10.1002/anie.2…
Proud to celebrate Ephrahime Traore and Romie Nguyen on earning their PhDs! 🎓✨ Watching you grow as scientists has been a true privilege. You’ve tackled tough experiments, late-night writing, and endless revisions! Excited to see where science takes you next! Congratulations!
The world of enzyme catalysis is expanding! Ms Graciano & @Dr_Feradical highlight the increasing diversity of protein-derived cofactors, crucial for enzyme innovation. Read their review: doi.org/10.1039/d4cs00… #enzyme #biocatalysis #cofactor @UTSA @NSF @NIGMS @WelchFoundation
Check out our new publication! Structural insights into 2-oxindole-forming monooxygenase MarE: Divergent architecture and substrate positioning vs. tryptophan dioxygenases sciencedirect.com/science/articl… @WelchFoundation @jbiolchem
Whoa, hey there boss! Your innovative ideas and consistent support puts your students (us!) in optimal conditions to thrive. We are very happy to see UTSA recognize your efforts! @UTSAChemistry @UTSASciences @UTSAtoday utsa.edu/today/2024/11/…
Excited to share our new publication in JBC on the enol/keto tautomerization of oxaloacetate by ACMS decarboxylase (doi: 10.1016/j.jbc.2024.107878)! This finding highlights the need for further biological testing. #ACMSD #enzymology #Oxaloacetate #metabolism
Excited to share our new publication in JBC on the enol/keto tautomerization of oxaloacetate by ACMS decarboxylase (doi: 10.1016/j.jbc.2024.107878)! This finding highlights the need for further biological testing. #ACMSD #enzymology #Oxaloacetate #metabolism
Temperature is an important factor for pathogenic protein. See how KatG regulates its activity by an N-OOH adduct and uses its MYW cofactor to direct its oxidizing power towards peroxide decomposition rather than peroxidase activity @angew_chem @UTSA
Temperature is an important factor for pathogenic protein. See how KatG regulates its activity by an N-OOH adduct and uses its MYW cofactor to direct its oxidizing power towards peroxide decomposition rather than peroxidase activity @angew_chem @UTSA
New NIH grant! Join us to study amino acid metabolism, oxidation, crosslinking by metalloenzymes using Chem Biol, site-directed incorporation of noncanonical amino acids, spectroscopy, crystallography, and cryoEM (bit.ly/4daCqK9; contact: [email protected]) #ScienceJobs
We were very happy and honored to have lab alumnus Capt. Ian Davis join us for a dinner with the whole group. It was great to hear about your new work and life experiences and know that you are thriving, Ian! @GeorgiaStateU @UTSA @UTSAChemistry
The Liu lab Summer2024 pickleball competition was a great success. Our students need to work harder to improve their pickleball skills since @Dr_Feradical gave no quarter and decisively won! Can't let this happen again... @UTSAChemistry @UTSA @UTSASciences
ADO is pivotal in the regulation of oxygen sensing and thiol metabolism. We present evidence of a catalytic metal(3+)-bound superoxo intermediate, challenging the status quo of a high-valent ferryl intermediate in the thiol dioxygenase mechanism @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Rest in peace, Dr. Jarzecki
News of our own Dr. Ian Davis, at the Diagnostic Systems Division USAMRIID: His leadership has been instrumental in developing a groundbreaking blood testing protocol, using an innovative approach to significantly improve disease surveillance capabilities mrdc.health.mil/index.cfm/medi…
Check out the most recent work from Romie and how she revealed the structural rationale for the unprecedented high-spin ferric-hydroperoxo (also known as compound 0) in CYP121 bit.ly/46cFNfC. Congratulations Romie! Can’t wait to see your next new finding! @UTSASciences
Check out the most recent work from Romie and how she revealed the structural rationale for the unprecedented high-spin ferric-hydroperoxo (also known as compound 0) in CYP121 bit.ly/46cFNfC. Congratulations Romie! Can’t wait to see your next new finding! @UTSASciences
Congratulations @LiuFange !
UTSA faculty Prof. and Chair Audrey Lamb was elected as a 2022 AAAS Fellow in Chemistry. This is a significant recognition by a world-renowned scientific council. Congratulations! @UTSASciences @UTSA aaas.org/news/elected-f…
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