Flaherty Lab @FlahertyLab
Lab of Daniel Flaherty, Ph.D. Associate Professor of Medicinal Chemistry and Molecular Pharmacology at Purdue University. flahertylab.com West Lafayette, IN Joined August 2015-
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First author J. Med. Chem. paper released and defending your PhD on the same day?! That’s a great day @Katrina_Holly98! Very proud of our newly minted PhD from the lab!
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New paper out today from @Katrina_Holly98 and Prabhakara Rao Tharra on their work on development of bacterial carbonic anhydrase inhibitors against vancomycin-resistant Enterococci. They produced an analog with oral efficacy rescuing mice in a septicemic peritonitis model.
New paper out today from @Katrina_Holly98 and Prabhakara Rao Tharra on their work on development of bacterial carbonic anhydrase inhibitors against vancomycin-resistant Enterococci. They produced an analog with oral efficacy rescuing mice in a septicemic peritonitis model.
So proud of @Purdue_MCMP and @FlahertyLab grad student @molly_youse for successfully defending her PhD today! She did an amazing job and we are super excited for her next steps in her scientific career!
Very proud of @Purdue_MCMP grad student and lab member @molly_youse for being awarded the Jenkins-Knevel Award for Outstanding Graduate Research! This is the highest honor in the Purdue COP for grad research. Very well deserved!
Flaherty Lab retweeted
Design strategy from @FlahertyLab yields improved solubility for AC1 inhibitors with in vivo efficacy in rat model for inflammatory pain. #JMedChem go.acs.org/bu1
Flaherty Lab retweeted
Our postdoc position is still open! #malaria #ubiquitin #proteasome #protein degradation #UPR #artemisinin #resistance #drug resistance
Flaherty Lab retweeted
New ethoxzolamide analogs from @FlahertyLab show improved PK properties and efficacy in mouse model for gonococcal infection. #JMedChem go.acs.org/aDw
Our new paper from @Purdue_MCMP grad student @molly_youse is out. Molly designed new analogs of Ethoxzolamide with improved PK properties and anti-gonococcal activity leading to molecules with oral efficacy in a mouse model for N. gonorrhoeae infection. pubs.acs.org/doi/10.1021/ac…
New paper from the lab led by @Purdue_MCMP grad student @Katrina_Holly98 in collab with Groshong lab at NIAID Rocky Mountain Laboratories. Targeting the oligopeptide transport system in B. burgdorferi. frontiersin.org/articles/10.33…
Flaherty Lab retweeted
Covalent UCHL1 inhibitor with crystal structure and anti-metastatic properties from @FlahertyLab @WendtLab_cancer @kesslerlabox Read in #JMedChem here ➡ go.acs.org/8LT
New paper from the lab covalently targeting UCHL1. Great collab with @WendtLab_cancer @kesslerlabox and Das Lab @ClydeDadChitta! Screening, med chem, crystallography, Ub-proteomics, cellular activity all come together to tell the story. @Purdue_MCMP pubs.acs.org/doi/full/10.10…
Purdue @Purdue_MCMP grad student @molly_youse was awarded 1st Place in the Poster Competition at the 2nd Annual Antimicrobial Resistance Conference for her work in lead opt/studying small molecule properties that affect accumulation in Neisseria gonorrhoeae! Congrats!
I am honored to receive this title. Thank you to Chip and Jane Rutledge and to @purduepharmacy for the support!
I am honored to receive this title. Thank you to Chip and Jane Rutledge and to @purduepharmacy for the support!
Several Flaherty Lab and @Purdue_MCMP students were recognized at the @purduepharmacy Grad Student Research Day today. Congrats to Ryan Imhoff on the Jenkins-Knevel Award and Molly and Menna for poster awards! Thank you to the grad students in lab for all your contributions!
Congrats to @Purdue_MCMP and Flaherty lab grad students @molly_youse and @Katrina_Holly98 for winning best oral presentation and best poster, respectively, at the second annual Purdue University - Notre Dame Symposium! Tons of hard work paid off. Proud of these ladies.
Our department is hiring two positions. One in chemical biology and one in translational neuroscience. Come join a fantastic department with great colleagues!
Our department is hiring two positions. One in chemical biology and one in translational neuroscience. Come join a fantastic department with great colleagues!
Flaherty Lab retweeted
@Purdue_MCMP is hiring for Faculty Positions in Translational Neuroscience and Chemical Biology careers.purdue.edu/job-invite/282…
New paper from my group and @nglab_malaria on the identification of covalent inhibitors against P. falciparum UCHL3. Keep an eye on this work in the future from our groups 😉 @Purdue_MCMP @DrugDiscoveryPU @UNMC_PathMicro sciencedirect.com/science/articl…
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