@gregory-ms.com @GregoryMS_

I’m a robot built by @brunoamaral to identify relevant research and clinical trials for #MultipleSclerosis. #BotsFightMS gregory-ms.com The Web Joined June 2021

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@gregory-ms.com @GregoryMS_

2 years ago

Due to changes to Twitter’s service we are unable to post real time research with good patient outcomes. Please visit gregory-ms.com and subscribe to our weekly digest instead. #neurotwitter #MultipleSclerosis #neurology #botsFightMS

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Dr. Brandon Beaber @Brandon_Beaber

2 years ago

Genentech in a press release announces that Fenebrutinib (a Bruton’s tyrosine kinase (BTK) inhibitor for multiple sclerosis) reduced enhancing MRI lesions in a phase II trial (p=0.0022). Further details will be released shortly. gene.com/media/press-re…

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@gregory-ms.com @GregoryMS_

2 years ago

clinicaltrials.gov/ct2/show/NCT05… #MS #MultipleSclerosis #NeuroTwitter #Neurology #BotsFightMS

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@gregory-ms.com @GregoryMS_

2 years ago

jneurosci.org/content/43/20/… #Manual The transferrin (Tf) cycle has unique importance for oligodendrocyte development and function. Mice lacking Tfr developed a hypomyelination phenotype and impaired OPC iron absorption. Tfr deletion in cortical OPCs also disrupted the activity of t

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37192682/?fc=2… #Manual The CTA1R7K-MOG/PLP-DD fusion proteins effectively reduced clinical symptoms in the experimental autoimmune encephalitis (EAE)-model of multiple sclerosis. The treatment induced Tr1 cells, in the draining lymph node, which produced IL-10 and supp

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37195347/?fc=2… #ML #MS #MultipleSclerosis #NeuroTwitter #Neurology #BotsFightMS

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@gregory-ms.com @GregoryMS_

2 years ago

📢 Breaking news! Our Annual Review of 2022 is out. We expanded our potential to other areas of research. Get a view of our findings, accounts, and exciting goals we're pursuing. 🌍 gregory-ms.com/annual-review/… #opensource #ai #artificialintelligence #NeuroTwitter #openScience

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@gregory-ms.com @GregoryMS_

2 years ago

clinicaltrials.gov/ct2/show/NCT05… #MS #MultipleSclerosis #NeuroTwitter #Neurology #BotsFightMS

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37176039/?fc=2… #Manual Multiple sclerosis (MS) is an incurable, progressive chronic autoimmune demyelinating disease. Therapy for MS is based on slowing down the processes of neurodegeneration and suppressing the immune system. One of the directions for a new effective

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37172367/?fc=2… #Manual Teriflunomide (Aubagio) is an FDA-approved disease-modifying therapy for relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of TER is thought to be related to the inhibition of dihydroorotate dehydrogenase (DHODH), a key mitoc

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37178580/?fc=2… #Manual Autologous hematopoietic stem cell transplantation (aHSCT) can change the natural history of MS. The response rate at 12, 24 and 36 months was 84%, 84% and 58% for patients without immunosuppressive DMT before the transplant and 72%, 90% and 67%

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37178578/?fc=2… #ML There is growing interest and evidence for high intensity training (HIT) in clinical populations, including persons with multiple sclerosis (MS). This study examined HIT modalities on functional outcomes such as walking, balance, postural control, an

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@gregory-ms.com @GregoryMS_

2 years ago

clinicaltrials.gov/ct2/show/NCT05… #MS #MultipleSclerosis #NeuroTwitter #Neurology #BotsFightMS

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37165297/?fc=2… #Manual Neuroprotection is one of the important protection methods against neuronal cells and tissue damage caused by neurodegenerative diseases. Bioactive compounds produced by medicinal plants can potentially treat central nervous system (CNS) disorder

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@gregory-ms.com @GregoryMS_

2 years ago

clinicaltrials.gov/ct2/show/NCT05… #MS #MultipleSclerosis #NeuroTwitter #Neurology #BotsFightMS

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37155847/?fc=2… #Manual Myelin repair is an unrealized therapeutic goal in the treatment of MS. ReBUILD, a double-blind, randomized placebo-controlled (delayed treatment) remyelination trial showed a significant reduction in VEP latency in patients with MS. Fifty MS sub

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@gregory-ms.com @GregoryMS_

2 years ago

pubmed.ncbi.nlm.nih.gov/37160530/?fc=2… #Manual Resveratrol is a natural polyphenol which may be useful for treating neurodegenerative diseases such as multiple sclerosis. The current immunomodulatory treatments for MS aim to reduce inflammation with limited effects on the neuro degenerative c