Hongtao Yu Lab @Hongtao_Yu_Lab
Our lab studies the cellular mechanisms that govern chromosome inheritance and integrity. utsouthwestern.edu/labs/yu-hongta… Dallas, TX Joined April 2018-
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Happy to share our new paper @NatureComms showing that insulin-independent insulin receptor (IR) activation mechanism by peptide agonist which activate non-functional IR mutants that cause the insulin resistance syndromes.doi.org/10.1038/s41467…
STAG2 promotes the myelination transcriptional program in oligodendrocytes doi.org/10.7554/eLife.… Beautiful work by @Ningyan8 and @Hongtao_Yu_Lab! Congratulation Ningyan!
Our cryo-EM structure of VASH1-SVBP bound to microtubules comes out @eLife. Great collaboration with Luke Rice lab! doi.org/10.7554/eLife.…
A structure provides insight into how cohesin, a protein that mediates sister chromatid cohesion, entraps #DNA. Read the research in Science: ($) fcld.ly/0vebzlf
Our cryo-EM structure reveals how cohesin-NIPBL entraps DNA. Fantastic collaboration with @bxc82 lab. science.sciencemag.org/content/early/…
Our cryo-EM structure reveals how cohesin-NIPBL entraps DNA. Fantastic collaboration with @bxc82 lab. science.sciencemag.org/content/early/…
Congrats, Eunhee! 👏👏👏
Say farewell to @EunheeChoi12 ! We will miss you!
Exciting to see our work in press! A phenomenal collaboration with @Hongtao_Yu_Lab Researchers Solve Decades-Old DNA Mystery cns.utexas.edu/news/researche…
Read our latest #research on [#Insulin-like growth factor receptor], published with @SpringerNature in @NatureComms [Structural basis of the activation of type 1 insulin-like growth factor receptor] Read here: rdcu.be/bTths
Mooaar! "the loop-extruding complexes most frequently contained two cohesin molecules" science.sciencemag.org/content/early/… By @Hongtao_Yu_Lab @IlyaFinkelstein @ZhubingShi et al. Really fascinating 1 or 2 cohesins for bidirectional extrusion?🤔 Different assays > different conclusions? 🤔
Our cohesin loop extrusion paper is online @ScienceMagazine. Great collaboration with @IlyaFinkelstein lab at UT Austin. @Hongtao_Yu_Lab science.sciencemag.org/content/early/…
Putting a🎀on it! Released today @EMDB_EMPIAR & @PDBeurope, & published @eLife, the 3.2 Å #cryoEM structure of full-length #InsulinReceptor bound to 4 #Insulins by Emiko Uchikawa, Eunhee Choi, Guijun Shang, @Hongtao_Yu_Lab & Xiao-chen Bai from @utswnews. (1/2)

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