Yuval Itan @ItanLab
Human disease genomics, precision medicine and machine learning. Associate Professor at @IcahnMountSinai itanlab.org New York, USA Joined March 2018-
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Yuval Itan retweeted
Extremely proud to see this published in @JExpMed. Kudos to Marjon Wouters and thank you @alexbolze @ItanLab @ERC_Research and @FWOVlaanderen. Have a look:
Extremely proud to see this published in @JExpMed. Kudos to Marjon Wouters and thank you @alexbolze @ItanLab @ERC_Research and @FWOVlaanderen. Have a look:
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Yuval Itan retweeted
1/ 🧬Excited to share that our study entitled Dominant negative ADA2 mutations cause ADA2 deficiency in heterozygous carriers led by @IsabelleMeyts, has been published in @JExpMed : hubs.la/Q03FRV7l0
Yuval Itan retweeted
Dogs are humanity's best friend—but how long has it been that way? 🐕 This Science study investigated ancient dog genomes, revealing a complicated genetic legacy that reflects a long, shared history with humans. Learn more on #InternationalDogDay: scim.ag/4mQjPbv
Yuval Itan retweeted
LDAK-KVIK is our new tool for mixed-model association analysis (MMAA) of quantitative and binary traits. LDAK-KVIK has the power of BOLT-LMM, but the computational demands of REGENIE. See the tweets below for more information.
Yuval Itan retweeted
A MUST-READ Review on Penetrance of Human Monogenic Inborn Errors (of Immunity, or not): Incomplete penetrance in inborn errors of immunity: A skeleton in the closet—The sequel rupress.org/jhi/article/1/…
Yuval Itan retweeted
Published today. Our review on Incomplete Penetrance. Four governing principles. Details here. 👇🏼@Columbia @KidsAtColumbia @ColumbiaGenDev rupress.org/jhi/article/1/…
Yuval Itan retweeted
Tracing the evolution of sequencing into the era of genomic medicine. #Sequencing #GenomicMedicine #Review @NatureRevGenet nature.com/articles/s4157…
Yuval Itan retweeted
.@alexisjbattle & co. from @AJHGNews' latest article developed GLEANR, a computational method to identify genetic pathways shared among complex traits, presenting it as a powerful tool for discovering both trait-specific and trait-shared pathways: bit.ly/3UZ5vAV #ASHG
Yuval Itan retweeted
PhD position opening in my lab! Grab your chance to dive into the genetics and pathophysiology of inborn errors of immunity and apply! @FWOVlaanderen @ERC_Research @Info4PI @KU_Leuven funded, in an international spirit. kuleuven.be/personeel/jobs…
Yuval Itan retweeted
Google’s research on a Personal Health Large Language Model (PH-LLM) is now published in @NatureMedicine Magazine!
Yuval Itan retweeted
A superb Review on a new syndromic IEI, due to GOF mutations in G protein-encoding GNAI2: MAGIS syndrome: Phenotypes, pathogenesis, and treatment rupress.org/jhi/article/1/…
Yuval Itan retweeted
Latest from us. Universal antiviral made! How? Transient gene therapy. Which genes? Only 10 suffice, out of thousands of antiviral host genes. How did we choose? Got inspired by patients and gene promoters. Read in detail 👇🏼 science.org/doi/abs/10.112…
Yuval Itan retweeted
Gene-Set Enrichment Analysis and visualization on the web using EnrichmentMap: RNASeq. #GSEA #WebTool #RNAseq @BioinfoAdv academic.oup.com/bioinformatics…
Yuval Itan retweeted
Our paper is now out in final form at Nature Genetics! For those who missed the preprint, we used large-scale Perturb-seq targeting transcription factors to push primary fibroblasts into diverse transcriptional states, including those observed in cell atlas studies.
Yuval Itan retweeted
Nature research paper: Whole-genome sequencing of 490,640 UK Biobank participants go.nature.com/45KBcTN
Yuval Itan retweeted
Decoding nature’s grammar with DNA language models. #Genomics #LLMs #AI @PNASNews pnas.org/doi/10.1073/pn…
Yuval Itan retweeted
Parabricks, a genomics startup with the goal to GPU-accelerate NGS analysis, was acquired by @nvidia in 2019. The Parabricks team has recently published their body of work showing GPU-accelerated, universal analysis that supports a wide range of sequencing platforms - including…
Yuval Itan retweeted
Can LLMs predict the results of CRISPR screens in silico, before the experiment is run? A team led by Aly Khan, AI/ML head at #CZBiohubCHI, has built a scalable LLM-based prediction framework. Read the 📃 just accepted to #BioNLP workshop at @aclmeeting! aclanthology.org/2025.bionlp-1.…
Yuval Itan retweeted
Our Japanese multi-omic immune cell atlas is out in @NatureGenet! We projected omics layers — from germline/somatic mutations to metagenomics — into single-cell space to uncover dynamic immune regulation. nature.com/articles/s4158…
Yuval Itan retweeted
A postdoc position is open in my lab to develop AI/ML models for predicting functional effects of genetic variants and to lead large-scale PheWAS in major biobanks. Strong programming skills, a solid publication record, and a background in human genetics are required.
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