Journal of Clinical Psychopharmacology @JCPjournal
Journal of Clinical Psychopharmacology keeps clinician-scientists and trainees up-to-date on the latest clinical developments in psychopharmacologic agents. psychopharmacology.com Lippincott Williams & Wilkins Joined January 2011-
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A 2025 Executive Order calls SSRIs a “threat” to youth. Our latest editorial and podcast revisit the evidence: #SSRIs remain safe, effective, and essential for many youth with anxiety, depression, and OCD. 🎧 Podcast: jcpjournal.libsyn.com/fact-versus-fe… 📰 Editorial: journals.lww.com/psychopharmaco…
In treatment-resistant #depression, positive mental health (PMH) — hope, confidence, meaning — predicted remission better than symptom severity. PMH improved most with #aripiprazole. Measuring PMH may guide next-step care. 🎧 jcpjournal.libsyn.com/how-does-posit… 📰 journals.lww.com/psychopharmaco…
Our September/October 2025 issue (Volume 45, issue 5) is now available online: journals.lww.com/psychopharmaco… Brief synopsis of the new issue from the Journal of Clinical Psychopharmacology Editor-in-Chief is below.
A new case in JCP details extreme nonmedical use of #tranylcypromine: a patient took up to 2400 mg/day over nearly 10 years, far exceeding safe limits. The report underscores the drug’s abuse potential and the need for careful monitoring in complex cases. journals.lww.com/psychopharmaco…
A new systematic review explores the potential of #chromium and #selenium supplementation to support treatment of psychiatric symptoms. Preliminary evidence suggests benefits for mood, anxiety, and obsessive-compulsive symptoms. More in our current issue: journals.lww.com/psychopharmaco…
Glucagon-like peptide-1 receptor agonists, best known for treating diabetes and obesity, may also reduce alcohol use and relapse risk in alcohol use disorder. Read more in our current issue: journals.lww.com/psychopharmaco… #psychopharmacology #addiction #AUD #GLP1 #systematicreview
A recent open-label trial found that #methylphenidate significantly improved emotion dysregulation in most children, but for those who didn’t respond, #aripiprazole — either alone or in combination — proved effective. Read more in our current issue: journals.lww.com/psychopharmaco…
In >20K patients with MDD, #pharmacogenomic testing led to 39% fewer significant gene-drug interactions and reduced psychiatric hospitalizations and ED visits. PGx-guided care shows real-world impact. Read more: journals.lww.com/psychopharmaco…
Can a patient's family history of medication response help guide treatment for mood disorders? Although this approach is widely used, a new systematic review finds that the supporting evidence is limited. 📘 Article: journals.lww.com/psychopharmaco… 🎧Podcast: jcpjournal.libsyn.com/a-systematic-r…
Are doctors being subtly influenced by the #pharmaceutical industry — even through e-prescribing alerts? Dr. Jeffrey Mattes’ guest editorial and podcast expose how marketing shapes clinical decisions. 🎧 Podcast: jcpjournal.libsyn.com/how-does-drug-… 📰 Editorial: journals.lww.com/psychopharmaco…
A new retrospective study of 14 pregnancies in women with schizophrenia treated with #clozapine found a 36% #miscarriage rate, but no congenital malformations among live births, normal infant growth, and no adverse effects during breastfeeding. 🔗 journals.lww.com/psychopharmaco…
A newly published case report in JCP presents what may be the first documented instance of a #manic episode potentially triggered by #primidone in a patient with essential tremor and a history of depression. 🔗 journals.lww.com/psychopharmaco…
Rare impulse control problems associated with #aripiprazole may be overlooked. A new case series highlights two patients with prior substance use disorders who developed compulsive substance use while on aripiprazole, which resolved after discontinuation. journals.lww.com/psychopharmaco…
Developing a Clozapine Titration Monitoring Algorithm: Integration of Evidence and Clinical Experience at a University Hospital dlvr.it/TLynZ4
New study of over 120,000 #clozapine therapeutic drug monitoring samples finds #smokers may need lower #plasma levels than nonsmokers for treatment-resistant #schizophrenia. Adverse drug reactions appear earlier in nonsmokers, particularly in women. 🔗 journals.lww.com/psychopharmaco…
How Does Drug Company Marketing Affect Physician Prescribing? dlvr.it/TLwhHR
In a new study from Mayo Clinic, EHR-derived outcomes (like antidepressant non-refill) were tested as proxies for treatment response. Findings support non-refill as a scalable, real-world measure of antidepressant tolerability. Read more in our new issue: journals.lww.com/psychopharmaco…
Childhood Bruxism Associated With Sertraline Dose Increase: A Case Report dlvr.it/TLvg2Q
Question: Is it safe for people with cancer and other serious conditions to combine cannabidiol with melatonin when neither has worked well enough for insomnia when used alone? dlvr.it/TLrDJ4
Can a patient's family history of medication response help guide treatment for mood disorders? Although this approach is widely used, a new systematic review finds that the supporting evidence is limited. 📘 Article: journals.lww.com/psychopharmaco… 🎧 Podcast: jcpjournal.libsyn.com/a-systematic-r…
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