Serological clusters in systemic #lupus erythematosus and its clinical and prognostic implications (#RELESSER registry, n = 1,740 patients)
◦ Cluster 1 (negative for ENA, 44.5%): lower frequency of vasculitis, leukopenia, and lymphopenia.
◦ Cluster 2 (positive aPL antibodies,…
⚠️Y el problema no es el p-valor… sino cómo lo usamos.
🧠¿Qué puedes hacer mejor?
- Informa los resultados exactos, no uses estrellitas.
- Utiliza medidas de efecto.
- Piensa en términos de coste-beneficio y riesgo, no solo en “significativo o no”.
- Considera el tamaño muestral
#Obinutuzumab, a humanized anti-CD20 monoclonal antibody with deeper B-cell depleting capacity compared to #rituximab, is a potential treatment for refractory idiopathic inflammatory #myopathies with severe #musculoskeletal and #lung involvement, as demonstrated by the recently…
2K Followers 2K FollowingRheumatologist. Associate Prof. of Med. Co-Director, Director of Clinical Trials Hopkins Myositis Center. Co-Director, Hopkins Autoimmunity Center of Excellence
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2024 Impact Factor: 2.8
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Profesor Titular en UEM.
Codirector Master eco-MSK en UAH
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5K Followers 56 FollowingPublishing high-quality clinical, therapeutic and translational research for the practicing Rheumatologist. Impact factor 5.431. An Elsevier journal.
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2K Followers 909 FollowingCreated in 2000 as the first glomerular disease center in the United States, we are dedicated to the care of people with rare diseases of the glomerulus.