Laurence Legeai-Mallet_Lab @LLM_Lab
Lab interested in molecular and physiopathological bases of osteochondrodysplasia with a focus on FGFRs related skeletal dysplasia @institutimagine @Univ_Paris institutimagine.org/fr Imagine Institute,Paris,FRANCE Joined January 2022-
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Congrats to Lea and the team of @LLM_Lab @InstitutImagine
Congrats to Lea and the team of @LLM_Lab @InstitutImagine
I am pleased to announce my thesis publication in @JCI_insight on Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralisation in mice buff.ly/3XzexFv . Thanks to my amazing mentors and colleagues @LLM_Lab
#Cover: Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice: buff.ly/3XzexFv Image: μCT image of the fifth lumbar vertebra of a 10-week-old mouse. @LLM_Lab @Inserm #BoneBiology #Genetics
Encore l'@InstitutImagine à la société américaine de génétique Los Angeles 2022 : communication sélectionnée de Laurence Legeai-Mallet @LLM_Lab sur les essais pré cliniques dans l’hypochondroplasie, avec QED Therapeutics ! #ASHG22
@JeromeGuicheux @GordonConf @RMeS_UMR1229 @LLM_Lab @ColnotLab Always fun to be around the Frenchies … Having a nice time at the meeting
project partners are @TomVanAgtmael @TheRuggieroLab @aforlino @MD_Briggs @FZaucke @KasiaPirog1 @BonaldoLab #evercyte #medetia @LLM_Lab @LifeTecGroup
Cornille et al @LLM_Lab show that FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model bit.ly/3HTBVns From our #Neuroimmunology & #Neurodegeneration collection: bit.ly/38Ermcv #KSNeuroImmune22 #KSNeuroDegen22
Maxence Cornille, Stéphanie Moriceau, Laurence Legeai-Mallet @LLM_Lab and colleagues suggest that modulation of the FGFR3 signaling pathway might be of value for treating the neurological and cognitive impairments observed in craniosynostosis. bit.ly/3HTBVns
Happy to finally share our study on « Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia » now published rdcu.be/cGaie #BoneRes #achondroplasia #epicatechin #FGFR3 #primarycilia @NaturePortfolio @SpringerNature
Looking at a zebrafish head to see what’s happening in skull sutures. It's the objective of our starfish team composed of Dr Emilie Dambroise, Rachel Pereur (PhD student) and Yvan Marc (engineer) doi.org/10.1002/jbmr.4…
#LesRDVdelaRecherche🔬 Notre 1er RDV de la recherche de l'année c'est mardi pro avec les Pr Valérie Cormier-Daire & Laurence Legeai-Mallet pour une présentation sur "Un nouveau traitement pour #achondroplasie". #maladiesrares 👀 Vite inscrivez-vous ➡ forms.gle/uuM1cF2szCdqgW…
For whom interested in the association of BMN111 and LB100 in achondroplasia treatment. See our last publication in collaboration with Dr. Laurinda Jaffe doi.org/10.1172/jci.in…. #jciinsight #achondroplasia #Bones #cartilage @InstitutImagine @UConn
Hello, We are new on tweeter, we are a bone and cartilage research lab with a focus on FGFR3. Now, connected to the scientific community and we will be delighted to share exciting science. @InstitutImagine #ECTS #ASBMR

Umarevathy @Umarevathy2
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Vinatier Claire @ClaireVinatier
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LBI Trauma @lbitrauma
277 Followers 163 Following official account of the Ludwig Boltzmann Institute Traumatology, The Research Center in Cooperation with AUVA
Conny Schneider @currifex
408 Followers 602 Following cartilage TE @lbitrauma, open innovation @LBG_SHoW * enjoys biochemistry, cell culture, imaging * science communication, webdesign and administration
Caroline Caetano @ccaetanodasilva
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The Kusumbe Lab @Anjali_Kusumbe
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Ludovic MARTIN @BouhoursMartin
0 Followers 34 Following
Andrique Caroline @ndrqcaro
40 Followers 164 Following 🇫🇷 Midwife student/Post-doc @LabBRIO_UP @Univ_Paris #midewifery #bonebiology #mineralizedtissue
Pooja Dudeja @654Dudeja
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ColnotLab @ColnotLab
246 Followers 138 Following We study the biology of stem/progenitor cells in musculoskeletal development, regeneration and diseases.
Kasia Pirog @KasiaPirog1
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ECTS_Science @ECTS_science
2K Followers 1K Following European Calcified Tissue Society @ECTS_soc Science account maintained by the social media action group of researchers. #ECTS2025
surfeclaire @soudaisclaire
5 Followers 18 Following
helendietmar @helendietmar
118 Followers 225 Following Postdoc in Heidelberg🇩🇪, with an interest in cartilage & extracellular matrix biology. Views are my own. PhD from @UniofNewcastle @IGM_skeletal 🇬🇧🇪🇺
JCI insight @JCI_insight
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Maxime Taverne @DrMaximeTaverne
14 Followers 67 Following Postdoc fellow at Necker Pediatric Hospital, Paris
Meriem GARFA TRAORE �... @Meriem_GT
61 Followers 157 Following Head of Cell Imaging Facility at Necker campus (@SfrNecker, @NeckerInem, @InstitutImagine)
Tilotta Françoise @TilottaFra
3 Followers 23 Following DDS, PhD, @LabBRIO_UP, Université Paris Cité, AH-HP
Sciomics GmbH @sciomics
373 Followers 444 Following Enabling Precision Medicine through Advanced Protein Biomarkers
International Achondr... @ACHONforum
159 Followers 111 Following A free online resource specialising in achondroplasia education and research. New website now live! #IAF
Musab Bin Umair @musabumair98
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Agnes Linglart @AgnesLinglart
565 Followers 382 Following
Claude Griscelli @CGriscelli
178 Followers 194 Following Professeur de PÈdiatrie et de génétique médicale. directeur général honoraire de l INSERM. Fondateur d Imagine (institut des maladies génétiques
Yanrong Cai @CaiYanrong
49 Followers 240 Following PhD student @UniHeidelberg #osteoimmunology#stem cell# cartilage bone repair
Stains_Lab @Stains_Lab
1K Followers 2K Following @Joe_Stains lab. Discovering the molecules and pathways that regulate bone. #osteoblast #osteocyte #cytoskeleton #sclerostin #gapjunction #bone #science
Melita Irving @melitairving
391 Followers 348 Following Bones, genomes and varietal clones 🍇 And now published author on Human DNA - Understanding your genetic code (Mother of two and clinical geneticist too)
Ryan Jones @Jones__Ryan
145 Followers 303 Following Research associate Biomechanics & Bioengineering Research Centre Versus Arthritis Cardiff University
Naomi Dirckx @NaomiDirckx
674 Followers 657 Following Passionate bone biologist | Cell metabolism | Assistant Professor @washu_ortho_res & @WashU_MRC | Nature lover | 🇧🇪
Joel Boerckel @jboerckel
8K Followers 4K Following Mechanobiology of development & regeneration. Assc Prof: @PennMedicine @PennBioeng. Co-Dir: @McKayLaboratory. Dir: @Penn_PCMD Biomechanics Core. Prov. 25:2. 🦛
WashU MRC @WashU_MRC
663 Followers 326 Following Washington University Musculoskeletal Research Center Improving musculoskeletal health through basic and translational research NIH P30 AR074992, T32 AR060719
Beacon for Rare Disea... @RareBeacon
12K Followers 10K Following Beacon is a UK-based charity that is building a united rare disease community with patient groups at its heart. Previously known as Findacure.
Omar Abdallah @OmarHMAbdallah
76 Followers 146 Following PhD fellow in Cardiovascular Medicine @UofGlasgow @Change_ECM | @ImperialCollege - Molecular Medicine
Anna Guller 🇺🇦�... @anna_guller
853 Followers 2K Following 🇺🇦🇦🇺 Experimental pathologist & biophysicist. Tissue engineering, nanoresearch, and imaging. Regeneration, fibrosis and cancer. MQRF @Macquarie_Uni
ADEBAYO OLUWAFEMI ADE... @Kunlebayo2
766 Followers 4K Following PhD Student @NAU. Exploring Aging, Redox Biology, Exercise, & Phytochemicals. Research enthusiast & health advocate. 🧬💪 #Science #Health
GeertCarmelietLab @GeertLab
682 Followers 274 Following Skeletal cell metabolism and hypoxia signaling in bone development, regeneration and bone disorders @KU_Leuven
EZS European Zebrafis... @eu_fish
2K Followers 940 Following The European Zebrafish Society (previously The European Society for fish models in biology and medicine EUFishBioMed)
Miccio lab @LabMiccio
455 Followers 572 Following gene therapy, genome editing, lentiviral vectors, sickle cell disease, beta-thalassemia, red blood cell, hematopoietic stem cell
ThalinZar @ThalinZar
131 Followers 419 Following
sidki @sidki5
17 Followers 234 Following
Skeletal_Research_Gro... @IGM_Skeletal
312 Followers 316 Following Our research bridges rare and common skeletal diseases in a holistic approach to understand cartilage development and ageing.
Mégane Brusson @MeganeBrusson
230 Followers 2K Following Post-doctoral researcher @LabMiccio @ImagineInstitut | Gene therapy for β-hemoglobinopathies 🧬🦠🔬| EHA-ASH #TRTH2024
LP2M @LP2M_Lab
144 Followers 157 Following Research lab working on pathophysiology with major interest in immunology, osteoimmunology, ion transport and metabolism
IZFS4Planet @IZFSenvironment
592 Followers 725 Following Everything to make research activities more environmentally sustainable and to promote research helping to save the environment! Official Account of @InfoIZFS
KarsentyLab @KarsentyLab
313 Followers 366 Following Karsenty Lab @Columbia : Bone biology, Osteocalcin, Whole-organism physiology
Jerome Ezan @JeromeEzan
365 Followers 678 Following INSERM researcher at @PlanarPolarityT / @NCMagendie / @Neuro_Bordeaux/ @UnivBordeaux. @IcahnMountSinai alumni. Cell and developmental biology are my favorite!
MCDS-Therapy @MCDS_Therapy
699 Followers 2K Following An @EU_H2020 funded clinical trial for the treatment of #RareDisease MCDS. Any related tweets reflect only the views of the project owner.
International Achondr... @ACHONforum
159 Followers 111 Following A free online resource specialising in achondroplasia education and research. New website now live! #IAF
Kasia Pirog @KasiaPirog1
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ColnotLab @ColnotLab
246 Followers 138 Following We study the biology of stem/progenitor cells in musculoskeletal development, regeneration and diseases.
Claude Griscelli @CGriscelli
178 Followers 194 Following Professeur de PÈdiatrie et de génétique médicale. directeur général honoraire de l INSERM. Fondateur d Imagine (institut des maladies génétiques
RUBICON network @rubicon_network
191 Followers 84 Following EU-funded Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders
Skeletal_Research_Gro... @IGM_Skeletal
312 Followers 316 Following Our research bridges rare and common skeletal diseases in a holistic approach to understand cartilage development and ageing.
SYBIL_news @SYBIL_news
111 Followers 91 Following Systems biology for the functional validation of genetic determinants of skeletal diseases
Cambridge Rare Diseas... @camraredisease
8K Followers 6K Following making #rarediseases an everyday conversation https://t.co/kZWskP9Ojj
Rick Thompson @RickSThomp
718 Followers 307 Following Evolutionary biologist, turned CEO for Beacon: for rare diseases. All views my own.
MCDS-Therapy @MCDS_Therapy
699 Followers 2K Following An @EU_H2020 funded clinical trial for the treatment of #RareDisease MCDS. Any related tweets reflect only the views of the project owner.
Thomas Funck-Brentano @tfunck
361 Followers 307 Following Bone physiology & Rare bone diseases. Professor at Université Paris Cité Inserm 1132, Lariboisière hospital APHP
Nice Osteoimmunology ... @Blin_C_Lab
414 Followers 196 Following Research team, osteoimmunology fan, osteoclast lover, passionate about immunology and fascinated by the gut-bone dialog
Natalie Butterfield @futurenat
215 Followers 194 Following Inquisitor of things. Runner of distance. Post-doctoral researcher in bone and cartilage biology, osteoarthritis and endocrinology at Imperial College
Agnes Linglart @AgnesLinglart
565 Followers 382 Following
KarsentyLab @KarsentyLab
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Melita Irving @melitairving
391 Followers 348 Following Bones, genomes and varietal clones 🍇 And now published author on Human DNA - Understanding your genetic code (Mother of two and clinical geneticist too)
The Chandler Project ... @thechandlerproj
80 Followers 187 Following Providing advocacy 📣 awareness 💡 research 🔬 & support 💜 for #achondroplasia, #hypochondroplasia, and other skeletal dysplasias 🧬
Achondroplasia Resear... @ach_research
296 Followers 646 Following Keep up with the latest in #achondroplasia and #skeletaldysplasia research on threads 🧵 link below
Thomas Bourgeron @ThomasBourgeron
523 Followers 360 Following
Inês Alves @InesA_Beyond
158 Followers 220 Following People’expert on Skeletal Dysplasia, CHRC-University of Évora, COMP-EMA member, ERN BOND ePAG, European Rare Bone Forum board member
Frank Zaucke @FZaucke
630 Followers 862 Following ECM biochemist interested in cartilage, Co-Chair Cartilage GRC 2023 Head of the Dr. Rolf M. Schwiete Research Unit for Osteoarthritis
Orthopaedic Research ... @ORSsociety
9K Followers 1K Following The home of your global orthopaedic research community. Accelerating musculoskeletal discovery to improve health. #orthoresearch #ORSAmbassador #ORSSMC #ORS2026
Roman Hossein Khonsar... @RH_Khonsari
558 Followers 638 Following Chirurgien @aphp @hopital_necker & Prof. @Univ_Paris Directeur médical @healthdatahub Directeur labo https://t.co/vxuA151Vzb @institutimagine
Guillaume Canaud (MD,... @CanaudLab
2K Followers 670 Following Translational medicine. Hôpital Necker Enfants Malades/Université Paris Cité.
Debrach Anne-Cécile @DebrachAnneC
191 Followers 515 Following Medical doctor, Rheumatologist (constitutional bone disorders, osteoporosis) @hug_ge. Tennis player. World citizen. Altruism. Views are my own
Filière TETECOU @FiliereTETECOU
638 Followers 475 Following Filière de Santé Maladies Rares des malformations de la tête, du cou et des dents
Jerome Lafont on the ... @JeroLafont_LBTI
21 Followers 37 Following Skeletal biology & diseases, tissue engineering @ROAD_Lbti and @UnivLyon1- Assistant professor in the group of Research on OsteoArticular & Dental tissues.
Hervé Kempf @hervekempf
216 Followers 168 Following Chercheur INSERM. Calcification dans les pathologies vasculaires et ostéoarticulaires.
OSCAR @FiliereOSCAR
497 Followers 161 Following La filière de santé maladies rares OSCAR : le réseau des maladies de l'os, du calcium et du cartilage
Marie de Bazelaire @MdeBazelaire
382 Followers 229 Following Directrice de la Communication @ Institut Imagine
EZS European Zebrafis... @eu_fish
2K Followers 940 Following The European Zebrafish Society (previously The European Society for fish models in biology and medicine EUFishBioMed)
International Society... @ISBM_society
1K Followers 779 Following The ISBM seeks to establish standards for all aspects of the quantitative imaging and analysis of skeletal tissues and to support researchers in these fields.
Jeroen Geurts PhD @OA_Lab_CHUV
458 Followers 419 Following PI in Translational Osteoarthritis & Bone Research @CHUVLausanne Associate editor @OACJournal / Member @AcademyEcts Let's advance MSK research together!
Stanislas Lyonnet @StanLyonnet
233 Followers 57 Following Directeur Général @InstitutImagine Pédiatre Généticien @Hopital_Necker & Professeur de Génétique @Univ_Paris
Michael Briggs 🔬�... @MD_Briggs
3K Followers 3K Following Professor of Genetics @ Newcastle University | Rare Disease Researcher & ECM Biologist | Yorkshire Cricket & Psychedelic Rock | Find me on the Fells 😊
SFBD-BioDev @sfbd_biodev
2K Followers 2K Following Official account of the French Society for Developmental Biology
Audrey Desgrange @Audreydsg
636 Followers 1K Following Permanent Researcher - CRCN @Inserm working @institutpasteur and @InstitutImagine 🔬. 💟 Morphogenesis addict. L'Oréal-UNESCO @4womeninscience ambassadress
Steve Stegen @SteveStegen
564 Followers 475 Following Assistant Professor @KU_Leuven | @AcademyEcts member | Passionate about skeletal research | Cell metabolism enthusiast
Laurent Mellier @LaurentMellier
753 Followers 769 Following Directeur du Développement et de la Philanthropie internationale @InstitutImagine #MaladiesGénétiques #santé #recherche #soin #enseignement #science #innovation
ZelzerLab @ZelzerLab
823 Followers 454 Following The Zelzer lab performs interdisciplinary research on the development and morphogenesis of the musculoskeletal and proprioceptive system 🐁🔬🦴🧬
Daniel Medina Cano @DanielMedinaC12
326 Followers 765 Following Postdoc, @TommyVierbuchen lab Previously @InstitutImagine, Cantagrel/Colleaux lab / I do mouse brain organoids to understand what makes each brain unique
IFMRS @IFMRSGlobal
869 Followers 414 Following We aim to advance MSK research globally in order to prevent and treat MSK diseases through sharing resources, raising public awareness, and providing education.
@ERN_RND 🧠 @ERN_RND
3K Followers 716 Following European Reference Network for Rare Neurological Diseases (ERN-RND) to improve diagnosis, care & treatment of RND patients. Free webinars: https://t.co/nowjhyNigm
ERN CRANIO @cranio_ern
524 Followers 142 Following The European Reference Network for rare and/or complex craniofacial anomalies and ENT disorders