🔬 New from the Farnung Lab: We have established a fully in vitro reconstituted chromatin replication system and we report the first cryo-EM snapshots of the human replisome engaging nucleosomes. 🧬✨tinyurl.com/replisome

🧩 Our structures reveal how replisomes unwrap nucleosomal DNA in a step-wise manner. Remarkable parallels to transcription! This is the fantastic work of Felix Steinruecke with support from @MarkertJon. Stay tuned!

@LucasFarnung Nice job!

@LucasFarnung Beautiful work

@LucasFarnung V cool (bonus cryo-EM pun)

@LucasFarnung Awesome! Congratulations to you all!