MACS @MACS_Project

The Manchester Acute Coronary Syndromes Project Manchester, England Joined January 2018

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Patricia van den Berg @patricia_vdberg

6 years ago

Just starting an interesting day on the T-MACS Network organised by @HealthInnovMcr to spread the word about a algorithm that still hasn't reached its full potential. healthinnovationmanchester.com/our-work/t-mac…

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Patricia van den Berg @patricia_vdberg

6 years ago

Are clinicians ever going to comfortable just to send patients home based on troponin only strategies? @HealthInnovMcr @MACS_Project

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Patricia van den Berg @patricia_vdberg

6 years ago

T-MACS is based on logistic regression. It isn't only great at rule out but also does a great job at ruling patients in as well. @HealthInnovMcr @MACS_Project

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Patricia van den Berg @patricia_vdberg

6 years ago

Machine learning can and hopefully will prepare TMACS to the future and make it even better. Great work by @Reynard_EM in progress. @HealthInnovMcr @MACS_Project

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Patricia van den Berg @patricia_vdberg

6 years ago

T-MACS stratification in ~1500 patients at MRI identifying 61% patients as very low or low risk with excellent sensitivity. @HealthInnovMcr @MACS_Project

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Health Innovation Manchester @HealthInnovMcr

6 years ago

@Cara_W_Afzal @richardbody @MACS_Project Other speakers this morning included Dr Stuart Monk, from @sw_ahsn who gave an overview of our role of spread and adoption of innovation & @patricia_vdberg from @OfficialUoM who presented on the shared decision making of the TMACS pathway. #TMACS @MACS_Project #weareHInM

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Health Innovation Manchester @HealthInnovMcr

6 years ago

Our Senior Programme Development Lead, @Cara_W_Afzal and @richardbody presenting this morning at the TMACS Network Event in #Manchester @MACS_Project #TMACS #weareHInM

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MACS @MACS_Project

8 years ago

2018 will be a big year for the #MACS_Project: (1) BEST study results (2) PRESTO study (pre-hospital) begins (3) Regional implementation (4) Some exciting new angles for the decision aids yet to come!

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MACS @MACS_Project

8 years ago

TMACS has been used at @MFTnhs since June 2016, & is now being rolled out across Greater Manchester as a @HealthInnovMcr exemplar project We'll keep you up to date as the project progresses in 2018!

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MACS @MACS_Project

8 years ago

You can find an easy to use #TMACS calculator at the fantastic @mdcalc site mdcalc.com/troponin-manch…

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MACS @MACS_Project

8 years ago

Originally, #TMACS and #MACSRule had only been shown to work with one assay: hs-troponin T The amazing @patricia_vdberg put that right by validating both with a contemporary assay (Siemens cTnI Ultra) ajemjournal.com/article/S0735-…

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MACS @MACS_Project

8 years ago

#TMACS was externally validated by some of the greatest Emergency Med researchers in the world, from Australasia @louiseacullen @LastCardiology @kiwiskiNZ emj.bmj.com/content/34/8/5…

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MACS @MACS_Project

8 years ago

For some, #HFABP was a barrier to using the #MACSRule. Labs aren't already running it. We refined the model, creating #TMACS: now the only biomarker needed is hs-troponin T emj.bmj.com/content/34/6/3…

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MACS @MACS_Project

8 years ago

Patients who took part in the #MACSPilot told us what they thought of their participation. Very valuable insights for all emergency research from this qualitative piece, led by @patricia_vdberg emj.bmj.com/content/early/…

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MACS @MACS_Project

8 years ago

A pilot RCT comparing the #MACSRule to standard care showed the feasibility of a large trial. Significantly more safe discharges occurred in the intervention group (26% v 8%, OR 5.45) emj.bmj.com/content/early/…

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MACS @MACS_Project

8 years ago

The awesome @EddCarlton ran an external validation of the #MACSRule - the first to be done outside Manchester onlinelibrary.wiley.com/doi/10.1111/ac…

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MACS @MACS_Project

8 years ago

There's also a blog post on the automated #HFABP assay stemlynsblog.org/macs-rule-new-… @stemlyns

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MACS @MACS_Project

8 years ago

If you're not in the mood to read a full paper on the #MACSRule, you might prefer to read the blog! stemlynsblog.org/the-macs-rule-…

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MACS @MACS_Project

8 years ago

One criticism was that the #MACSRule used an #HFABP assay that couldn't be run in the ED. @RandoxOfficial developed an automated assay to overcome that! It can be run on any lab analyzer emj.bmj.com/content/early/…