Thrilled to share our team's newest paper examining the cellular ecosystem of Primary Sclerosing Cholangitis, a rare liver disease that has no current treatments, a fact that we hope to change with our single cell, single nuc and spatial atlasing efforts! sciencedirect.com/science/articl…
In this work, led by the brilliant former postdoc and new faculty at UWO @talandrews and PhD candidate @DianaNakib, we used scRNA-seq (47,156 cells), snRNA-seq (23,000 nuclei) and spatial transcriptomics to profile the cellular ecosystem in 10 patients with PSC.
@MacparlandSonya @garybader1 @talandrews @DianaNakib @UHNTransplant @MbD_UofT @SickKidsNews @CIHR_IRSC @cziscience @PSCPartners @PSCPartnersCa Perfect timing, a quick glance at the shiny app identified all my favourite markers! Will bump this one up the todo list to dive into. Thanks and well done! #LeafsForever
@MacparlandSonya @garybader1 @talandrews @DianaNakib @UHNTransplant @MbD_UofT @SickKidsNews @CIHR_IRSC @cziscience @PSCPartners @PSCPartnersCa Congrats to the whole team, can’t wait to read!