How can we use high-density EMG (HDEMG) signals to control motoneuron (MN)-driven muscle models? We offer some answers and a validated and open-source 🤩computational method in our new published paper: 📜 doi.org/10.1371/journa… 💾 github.com/ArnaultCAILLET… 1/6

Spike trains from HDEMGs alone do not accurately predict the real neural drive to muscle and are not reliable inputs to muscle models. We developed a 4⃣-step method to predict the discharge behaviour of the complete population of MNs even from limited experimental data. 2/6

1⃣ The MNs identified from HDEMGs are located into the MN pool. 2⃣ The common MN membrane current is estimated from the experimental data. 3⃣ It controls models of discharging MNs, calibrated to match the recorded discharge frequencies. 3/6