NCI Human Tumor Atlas Network @NCIHTAN
Official Twitter account of the Human Tumor Atlas Network (HTAN), funded by the Cancer MoonshotSM Initiative. bit.ly/Moonshot-HTAN Joined November 2018-
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#HTAN adopted a set of data standards covering clinical, biospecimen, and assay metadata to promote interoperability across data sets. Specifications of these data standards can be found at humantumoratlas.org/standards.
Developed by @harvardmed #HTAN, ASHLAR is a computational package that allows researchers to stitch #HighPlex images together into high-dimensional mosaic images labsyspharm.github.io/ashlar/.
#HTAN investigators @WUSTLmed are determining mechanisms of breast and pancreatic cancer evolution in response to treatments and how #therapeuticresistance develops over time. humantumoratlas.org/hta12 #CancerMoonshot
Data generated through the collective efforts of the #HTAN Research Centers and Data Coordinating Center are available for #PublicAccess at humantumoratlas.org/explore.
DYK that the #IOTNCapstoneMeeting sharing scientific accomplishments in #ImmunoOncology across the @IOTNmoonshot will be May 14 & 15? Learn more and register at events.cancer.gov/dcb/iotncapsto…. #CancerMoonshot
TODAY at 12:00 pm ET, @IssakaMD @fredhutch and Dr. Francesco Tomassoni-Ardori @NCI_CCR_PedOnc will share #ImpSci & preclinical approaches to improve the early detection & treatment of cancer during a #CancerMoonshotSeminar. cancer.gov/research/key-i… #CMSSJI
On May 2 at 12:00 pm ET, Dr. Sarah Mullin @RoswellPark will discuss real-time #ArtificialIntelligence monitoring & the early detection of immune-related adverse events (#irAEs) during an @theNCI & @sitcancer computational #ImmunoOncology webinar: sitcancer.org/education/webi…
What causes responsive #ChildhoodCancers to become resistant? @KaiTanLab1 et al. @ChildrensPhila #HTAN are creating multi-omic atlases of #glioma, #neuroblastoma, and lymphoblastic B-cell #precursor #leukemia. humantumoratlas.org/hta4 #CancerMoonshot
Tomorrow! Listen to Dr. Kai Tan present a powerful and scalable method for de novo identification of condition-specific cellular clusters in tissue using #singlecell #spatialomics data at the Emerging Technologies virtual seminar. events.cancer.gov/cssi/technolog… #ETSS
Join us for a #CancerMoonshotSeminar on Thursday, April 25 at 12:00 pm ET! @IssakaMD @fredhutch and Dr. Francesco Tomassoni-Ardori @NCI_CCR_PedOnc will share #ImpSci & preclinical approaches to improve the early detection & treatment of cancer. cancer.gov/research/key-i… #CMSSJI
Human tumor atlases and related data, including sequencing, imaging, and clinical information, is available to the community in the #HTAN Data Portal. data.humantumoratlas.org/explore #CancerMoonshot
Join us at the #IOTNCapstoneMeeting on May 14 – 15 to learn about scientific accomplishments in #ImmunoOncology across the @IOTNmoonshot network. Additional information and registration can be found at events.cancer.gov/dcb/iotncapsto…. #CancerMoonshot
Developed by @Stanford #HTAN, ArchR is a set of computational tools for processing and analyzing #SingleCell #ATACseq, #scATACseq, and #scRNAseq data. github.com/GreenleafLab/A…
@NIH is collecting feedback on common data elements (CDEs) for #biomedical research. CDEs standardize data collection, boosting interoperability & knowledge discovery. If you have experience harmonizing CDEs in #CancerResearch then check this out: datascience.nih.gov/cde-rfi
On Thursday, April 25 at 12:00 pm ET, @IssakaMD @fredhutch and Dr. Francesco Tomassoni-Ardori @NCI_CCR_PedOnc will share #ImpSci & preclinical approaches to improve the early detection & treatment of cancer. cancer.gov/research/key-i… #CMSSJI
Do you have the guts to ruminate on the visceral thrill of this #Xenium image of #intestines made by @_hubmap researcher Dr. Chenchen Zhu @Snyder_Lab_SU @StanfordMed. Our gut feeling? It’s offal-ly intriguing! #intestine Goblet cells – cyan, stem like cells – dark red.
As part of National Cancer Prevention and Early Detection Month, @theNCI is dedicated to the #CancerMoonshot goal to prevent more cancers before they start + detect cancer early, when it’s most treatable. The #NationalCancerPlan helps guide these efforts. nationalcancerplan.cancer.gov/goals
How does #HTAN data reach the broader scientific community? The #HTAN Data Coordinating Center provides resources for data access, storage, analysis, and visualization to make research accessible to all researchers. humantumoratlas.org/htan-dcc #CancerMoonshot
Using #HTAN #CODEX antibodies to guide spatial #SingleCell proteomic profiling, @wang156658, @SnyderShot, @jingjingSF, et al. discovered key transcriptional factors driving placenta tissue differentiation @biorxivpreprint biorxiv.org/content/10.110….
Come hear from Kai Tan about the recently developed CytoCommunity algorithm to identify cellular neighborhoods in tissues using #singlecell #spatialomics data. Join us April 23rd to learn how this #informatics tool is being used in #CancerResearch! events.cancer.gov/cssi/technolog… #ETSS
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663 Followers 149 Following The CCMI is comprehensively mapping the molecular networks underlying cancer. We are a proud member of the NCI's Cancer Systems Biology Consortium.In a study funded by @MSKCancerCenter #HTAN, @dana_peer,@SettyM,@zining_choo, et al. developed SEACells, a computational tool to identify cell states from #SingleCell data @NatureBiotech via @NCIHTAN
@moni_e_brown delivering a lecture at the NIH_CZI Junior Investigators Atlas Builders Meeting. @NCIHTAN
The SMMART and AMTEC #ClinicalTrials are funded by @theNCI Human Tumor Atlas Network (@NCIHTAN). humantumoratlas.org #TranslationalSysBio #CancerMoonshot
@NCIHTAN has added new notebooks to ISB-CGC’s Community Notebook Repository! One of the new notebooks explores spatial cellular relationships using #BigQuery and #HTAN data. Check out the new notebooks at bit.ly/HTAN_notebooks @NCICancerBio #CancerMoonshot #CancerResearch
Latest data from @StanfordMed @NCIHTAN #PreCancerAtlas on #patients w/ #familialadenomatouspolyposis #FAP led by @SnyderShot #DrJimFord @cncurtis @WJGreenleaf @anshulkundaje
#HTAN2023: @khanaziz84 @Stanford is presenting evolutionary features of familial adenomatous polyposis (a genetic condition that increases one’s susceptibility to #colorectalcancer) #malignancy.
Honored to have been invited to present our work on segmentation-free cell state inference using variational autoencoders at the @htan Spring F2F meeting!
Dr. Gregory Baker @harvardmed is presenting how #ArtificialIntelligence can be used to infer cell states from #multiplex whole-side tissue imaging via the #computational tool MCMICRO (mcmicro.org) at #HTAN2023.
So excited to provide access to the #HTAN data on the @genomicscloud! learn how to access it at cancergenomicscloud.org or email us at [email protected] #CancerResearch #melanoma
Using the @velseraofficial @genomicscloud, #HTAN @harvardmed Melanoma Atlas #CyCIF data is available for public access and download. The Missing Manual provides further guidance on how to explore HTAN data: docs.humantumoratlas.org/access_control…. #MelanomaAwarenessMonth
#HTAN release 3 data has been added to ISB-CGC’s #BigQuery Ecosystem! Find the new data using our BigQuery Table Search tool at bit.ly/BQTableSearch and filter Program by HTAN. @NCIHTAN @NCICancerBio #CancerMoonshot
8) As part of @NCIHTAN, we demonstrate how one can use mouse models to provide gene programs to query our human LUAD dataset (cellxgene.cziscience.com/collections/ef…) and found T-reg cell fraction in tumors correlates with the same mouse derived inflammatory programs after t-reg depletion
Dr. Chenchen Zhu @Snyder_Lab_SU @StanfordMed uses #MolecularCartography to find different types of RNA within polyps from Familial adenomatous polyposis (FAP) patients, hoping to find ways to treat & diagnosis #ColorectalCancer more quickly. #HuBMAPImage #CellMapCrew #SciArt
@tangming2005 HTAN has lots of multiplexed imaging data coming through. @NCIHTAN humantumoratlas.org
Wonderful experience presenting our view of how pathology and computation are coming together to investigate cancer tissues at unprecedented depth. Best part was intro and Q&A moderated by the amazing @DrSMazz!! Thank you! @HiTSatHarvard @BWHPath @NCIHTAN @DanaFarber
ICYMI, the #CancerMoonshotSeminar with @SantagataLab @harvardmed #HTAN discussing multiplexed tissue imaging to reveal the #SpatialBiology of cancer can be viewed at youtu.be/8gWMytghieg. #CMSSHTAN
Looking forward to speaking!! Will talk about the tools we are developing in the HTAN, insights from 2D & early 3D about the spatial features of cancer, steps toward clinical implementation combining H&E and IF, and high res 3D multiplexing for probing cell biology in tissues.
Thursday, March 23 at 12:00 pm ET, @SantagataLab with the with the @harvardmed #HTAN will discuss the generation of pre-cancer atlases of cutaneous and hematologic origin. cancer.gov/research/key-i… #CMSSHTAN
Here’s a summary of the progress being made from @NCIHTAN, given by @DrShelleyHwang. In this video she speaks about the importance of #DataSharing for reducing cancer. youtube.com/watch?app=desk…
@StanfordMed #PreCancerAtlas focused on #patients w/#familialadenomatouspolyposis #FAP who have 100% lifetime risk of #colorectalcancer. 'Single-cell changes in the #malignant transformation of #polyps to #colorectalcancer' @NatureGenet nature.com/articles/s4158…
#HTAN researchers @StanfordMed, including @SnyderShot, @cncurtis, & @WJGreenleaf are generating a #PreCancer atlas of #ColorectalCancer to inform diagnostic, preventative, and therapeutic strategies. humantumoratlas.org/hta10 #CancerMoonshot
With so many multiplexed methods out there today, #datastandards will help with sharing, storing, and interpreting different datasets.
#HTAN adopted a set of data standards covering clinical, biospecimen, and assay metadata to promote interoperability across data sets. Specifications of these data standards can be found at humantumoratlas.org/standards.
The article explores the Human Tumor Atlas Network @NCIHTAN, @harvardmed’s Peter Sorger and colleagues’ work to create a melanoma map and @LambAlastair’s research on how #spatial transcriptomics could help improve early diagnosis of cancer future-science.com/doi/10.2144/bt…
Come check @NCIHTAN on the cgc.sbgenomics.com! Go to Cancer Data Service Explorer and look for phs002371! Ensure you have #dbgap permission to access controlled data or explore the open access images! Comment below or email us at [email protected] if you have questions!
#Genomic #HTAN data is now available via @NCBI #dbGaP and @genomicscloud. Additional information can be found at docs.humantumoratlas.org/access_control…. #CloudComputing #NCICommons
Josh Campbell and the BU group and Marc Ryser from our own team at Duke kicking off our fall HTAN meeting! Cutting edge science! @NCIHTAN @DukeCancer