Christoph Nitsche @NitscheLab
Chemical Biology Laboratory at the Australian National University nitschelab.com Canberra Joined January 2019-
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Dr Sven Ullrich talks about how RACI opens doors and builds your influence - we swear we didn't make him say any of this 🙌🏻 🌏 Ready to make your mark? Nominate today and join a network of changemakers. 🏆 bit.ly/4j7Q2Zf #RACI #ozchem #NationalAwards2025
We’ve been dreaming of this type of conjugation chemistry for years—and finally, a simple fix to a stubborn problem, all thanks to just a tiny drop of CS₂. Minimalist chemistry is the new gold. ✨
We’ve been dreaming of this type of conjugation chemistry for years—and finally, a simple fix to a stubborn problem, all thanks to just a tiny drop of CS₂. Minimalist chemistry is the new gold. ✨ https://t.co/gSXNTqxlmv
😊Delighted to share our latest #publication in collab with Dr. Rajendra Karki & colleagues from @SeoulNatlUni. In this @NatureComms paper, we show that #acrolein, a byproduct of our cells but also found in #cigarette smoke, #kills cells & contributes to #inflammation @ourANU 1/3
Check out our latest paper on @ChemEurJ Late‐Stage Intermolecular O‐Peptidylation Protocol Enabled by Sequential Acyl Transfer on Thiol‐Incorporated Threonine Followed by Desulfurization - Sato - Chemistry – A European Journal - Wiley Online Library …mistry-europe.onlinelibrary.wiley.com/doi/full/10.10…
Room temperature, selective C-H activation of arenes with aluminium in seconds!. All you need is an even more reactive aluminyl anion. Check out Fabian and Gareth's latest paper just accepted in @ChemicalScience @ANUChemistry #ozchem doi.org/10.1039/D5SC02…
Thank you @ANUChemistry for featuring our latest work! We've developed a greener, faster method for in vivo protein labelling — paving the way for better imaging and biosensing tools Read the article here: chemistry.anu.edu.au/news-events/ne… #GreenChemistry #SyntheticBiology
Curve the way for the RNA virus replication complex to work. #Chikungunya #virus "Saddle Curvature Association of nsP1 Facilitates the Replication Complex Assembly of Chikungunya Virus in Cells" biorxiv.org/content/10.110…
Congratulations to Prof Richard Payne for receiving over $741,000 in @NSWHealth Cardiovascular Senior Researcher grant funding! Find out more about the Cardiovascular Senior Researcher grants: tinyurl.com/38ytz7z5
Hot off the press in @NatureChemistry: Our paper on seed-competent stapled peptides that mimic the core fold of pathological tau! rdcu.be/ej4ik Huge congrats to Isaac, Ben, and collaborators in the Jiang and Vidal labs. #PeptideScience #tau nature.com/articles/s4155…
Really enjoyed presenting part of my PhD work at @RACInational #MCCB2025 in Darwin, reconnecting with the Australian MedChem and ChemBio community and seeing some crocodiles again too!
Huge thanks to @Chem_CP for highlighting our work on biosynthesis of nitrile amino acids and fast protein labeling Excited about the new possibilities in chemical biology and live-cell imaging. Thanks @ARC_CIPPS @ANUChemistry #ChemicalBiology #SyntheticBiology #ProteinEngineering
Huge thanks to @Chem_CP for highlighting our work on biosynthesis of nitrile amino acids and fast protein labeling Excited about the new possibilities in chemical biology and live-cell imaging. Thanks @ARC_CIPPS @ANUChemistry #ChemicalBiology #SyntheticBiology #ProteinEngineering
Pleased to see the review lead by Harry Shanley @Sleebs_Lab @WEHI_research in collaboration with the Gasser Lab @UniMelb on Advances in Anthelmintic Target Identification is now published. mdpi.com/3270800 #mdpiijms via @IJMS_MDPI
🤩 Check this out👇 A wonderful piece written by Calo Huang from @JCSMR on the research of @_AbhimanuPandey , @Cyn_Turnbull & Gavin Sutton #immunology #IBD #cancer #medicalresearch 🔗 jcsmr.anu.edu.au/news-events/ne… @ANU_Research @ourANU @scienceANU
Congratulations to @UpamaliSajinika from our lab for receiving the poster prize at the #MCCB2025!
Fantastic science this morning at #MCCB2025 from @raci award winners @PScammells and @NitscheLab . The development of bitopic ligands as biased #GPCRs agonists and tricyclic #peptides using cyanopyrine and bismuth chelation. Cool #chemistry
Fantastic science this morning at #MCCB2025 from @raci award winners @PScammells and @NitscheLab . The development of bitopic ligands as biased #GPCRs agonists and tricyclic #peptides using cyanopyrine and bismuth chelation. Cool #chemistry
Truly honoured to receive the #MCCB2025 Peter Andrews Award for Innovation in Medicinal Chemistry and Chemical Biology. Grateful for the recognition of our work at @NitscheLab and @ANUChemistry! Congratulations to @PScammells on the well-deserved Adrien Albert Award!
Truly honoured to receive the #MCCB2025 Peter Andrews Award for Innovation in Medicinal Chemistry and Chemical Biology. Grateful for the recognition of our work at @NitscheLab and @ANUChemistry! Congratulations to @PScammells on the well-deserved Adrien Albert Award!
One week until the applications close for our two postdoc positions: 1) Synthetic med chem usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_… 2) Chem bio usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_… (new links, not sure why Workday changed them...)
One week until the applications close for our two postdoc positions: 1) Synthetic med chem usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_… 2) Chem bio usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_… (new links, not sure why Workday changed them...)
biorxiv.org/content/10.110… Here’s a paper that was many years in the making. The idea that the climate can affect the thermodynamic mechanism of binding due to the temperature dependence of the entropy term is interesting- we see gradual shift in binding mode along evo trajectory

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American Peptide Soci... @ampepsoc
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bioRxiv @biorxivpreprint
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Ross Wang Lab @Rongsheng_Wang
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Dirk H. Trauner @DirkTrauner
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Nick Mitchell @mitchell_chem
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