Parth Shah @ParthSharesBio
Biotech exec sharing views on #healthcare & #biopharma | Passionate about #leadership and advancing medicines to reach patients | Tweets are my own | 🤝 linkedin.com/in/parthrshah California, USA Joined September 2013-
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ADCs are rapidly improving the way we treat every type of cancer. Their potential has been largely unleashed over the past 6 years— yet their technology is the result of a 100-year long, epic journey. Join @raffcolo & me to uncover 10 milestones in the development of ADCs (🧵):
"More than 85% of our small molecule pipeline is AI assisted" wrote AstraZeneca's Chief Data Scientist Biopharmaceuticals R&D & VP Jim Weatherall @weatheralljim75. "including AI-powered molecular insights to drive target discovery, design of new molecules, & predictive…
Why UPMC, Vanderbilt joined Aegis digital consortium modernhealthcare.com/digital-health…
Yikes. @IQVIA_global finds growing #PBM #formulary exclusions for #oncology #drugs. OK: #generic or #biosimilar alternatives Not OK: Exclusion of non-interchangeable therapeutic alternatives Also: Solid data on other patient access barriers ==> drugch.nl/3XfyYst
#News: The Federal Trade Commission has issued a statement of support regarding the new #FDA guidance on #interchangeable biosimilars, saying it could improve the approval process and reduce the burden and cost of #biosimilar studies. #FTC #pharmacy Read: bit.ly/3APynVm
Obesity's 'beefed up' clinical landscape: 77 clinical stage programs from 52 companies! Source: Evercore
This was a big week for my @Alnylam friends and colleagues, and it was because of a molecule once called ALN-TTRsc02, now vutrisiran or AMVUTTRA. Some of you may be curious to learn its story. 1/
Merus said Tuesday that the combination of its experimental drug petosemtamab with the checkpoint inhibitor Keytruda shrank tumors in 62% of patients with head and neck cancer. trib.al/dKfmaaF
Gravity-changing advance from @IsomorphicLabs and @GoogleDeepMind on AI-enabled drug discovery. Entering the "AlphaFold 3" era, now with protein-protein, protein-DNA and small molecule capabilities (also markedly improved primary structure prediction). The rising tide is just…
As competitive as oncology if not more on the high side…#immunology #oncology #biotech #pharma #drugdevelopment
As competitive as oncology if not more on the high side…#immunology #oncology #biotech #pharma #drugdevelopment
Biotech Consolidation: Not Really Happening. After two years of talk, that appears to be all it is right now… talk. Net numbers of publicly traded biotech down only 4.5%, hardly significant. lifescivc.com/2023/11/biotec…
One of the most powerful things we do at Amgen is to take the time to celebrate our shared mission for patients and recognize the work that we all do matters. Truly an inspiring day being with our team and hearing directly from the patients we serve. #AmgenMissionWeek #mycompany…
We set up the molecules in our portfolio as little companies and each one of those companies has a leadership team and board of directors. And they'll meet whenever they need to—and that's the way we provide the governance instead of the teams coming to committees for approvals.
RNAi (Alnylam), ASO (Ionis), Human Mabs (Regeneron), rDNA (Genentech, Biogen, many others)… Platforms are the only way to achieve sustainable innovation.
2023 Orphan Drugs: PDUFA Dates and FDA Approvals Click on the link below👇 to view the list of important regulatory dates for all orphan drugs for 2023. checkrare.com/2023-orphan-dr… #rarediseases #drugapprovals
The lessons we learn over and over.
The “Innovation Reduction Act?” An inspiring story by Dr. Ted Love. The #InflationReductionAct has some laudable provisions, but others that threaten to chill investment in the new #medicines we and our loved ones all need.
The “Innovation Reduction Act?” An inspiring story by Dr. Ted Love. The #InflationReductionAct has some laudable provisions, but others that threaten to chill investment in the new #medicines we and our loved ones all need.
Great contrarian take on eNPV in #drugdevelopment . But this is where the people and process beyond the data are critical in these high stakes decisions. The best leaders know when to take the eNPV off the table, or use it as an extra data point at most. You can often make a…
Great contrarian take on eNPV in #drugdevelopment . But this is where the people and process beyond the data are critical in these high stakes decisions. The best leaders know when to take the eNPV off the table, or use it as an extra data point at most. You can often make a…

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