Pelican Expression Technology @PelicanExpTech
Recombinant protein expression for vaccine development via the Pelican Expression Tech® platform & PeliCRM197® carrier protein. cGMP compliant & proven. pelicanexpression.com San Diego Joined December 2009-
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Our cGMP PeliCRM197® carrier protein is the only CRM197 available in milligram to kilogram quantities? This ensures your late-stage clinical development and commercial requirements are covered, de-risking your #supplychain and costs. bit.ly/3Ejpp16 #VaccineDevelopment
#DidYouKnow: Recombinant CRM197 expressed by Pseudomonas fluorescens is highly similar to #CRM197 produced by C. diptheriae? Unlike CRM197 produced by E. coli, the PeliCRM197® protein lacks N-Met residues, a common contaminant of heterologous proteins. bit.ly/3YTN7dU
Russ Coleman is the Director of Strain Engineering at @Ligand_LGND, managing early process development and workflow automation activities to enable high-yield production of difficult-to-express #therapeuticproteins. #PelicanExpressionTechnology #ProteinExpression
Our PeliCRM197® carrier protein is produced in compliance with Current Good Manufacturing Practices (cGMP) with inspections performed by multiple global health authorities, including the US FDA, UK MHRA, India CDSCO, and Health Canada since 2011. bit.ly/3Ejpp16
#DidYouKnow: CRM197 has been used as a carrier protein in conjugate vaccines for over 30 years! The first vaccine to use CRM197 was approved in 1990 to protect against Haemophilus influenzae type b (Hib). #TidbitTuesday
The Pelican Expression Technology® group has provided our PeliCRM197® carrier protein for vaccine development since 2011. Together, we can combat infectious diseases & make a #globalhealth impact. bit.ly/3Ejpp16 #NationalImmunizationAwarenessMonth
Proteins that fail to adequately express in other cell expression systems, such as E. coli and CHO cells, have been successfully produced by the Pseudomonas fluorescens-based Pelican Expression Technology® platform. #PelicanExpressionTechnology #ProteinExpression
The Pelican Expression Technology® platform integrates a variety of molecular assays to ensure the quantity and quality of proteins produced by our Pseudomonas fluorescens expression strains. Learn more: bit.ly/3KOmvoH
Ever wondered where the Pseudomonas fluorescens strain used to power our Pelican Expression Technology® originated? #PelicanExpressionTechnology #ProteinExpression #TidbitTuesday
An anthrax vaccine candidate incorporating a #recombinantprotein optimized and manufactured by the Pelican Expression Technology® platform has shown positive immunogenicity and safety data in Phase I clinical studies. sciencedirect.com/science/articl… #SuccessStories #clinicalstudies
Why choose a microbial expression system, like our Pelican Expression Technology® platform, over a mammalian system? Other microbes, like our P. fluorescens, are cheaper and faster to grow and often produce higher yields than mammalian cells! bit.ly/43mNFcX
Which features of DNA expression plasmids have you optimized to maximize your protein yield? Our Pelican Expression Technology® platform optimizes all of these features (and more!) at once using high-throughput screening. #ProteinExpression
A well-executed technology transfer for bioprocesses is critical for process and product reproducibility and quality. Learn how we can help: bit.ly/3DbAMb1
It's been 12 years since the publication of our seminal paper, "Reliable protein production in a Pseudomonas fluorescens expression system," where we first described our Pelican Expression Technology® toolbox. Give it a read here: bit.ly/43lFL3t #ProteinExpression
Meet Elizabeth Orchard, PhD, a Group Lead in Fermentation at Pelican Expression Technology®! Throughout her career, Elizabeth has developed upstream processes with various organisms, from algae to E. coli, and now Pseudomonas fluorescens! #MeetTheTeam
We're taking a moment to honor the accomplishments of Dr. Janet Mertz, whose contributions to the discovery of #recombinantDNA technology laid the groundwork for #biotechnology companies like ours. bit.ly/3rofHaP #ProteinExpression
Our Pelican Expression Technology® system combines a variety of codon-optimized genes, expression vectors, and P. flourescens phenotypes to produce thousands of unique expression strains to be screened in parallel. bit.ly/3pNEHaX #ProteinExpression
Our Pelican Expression Technology® system's technology uses #highthroughput screening to identify strains of P. fluorescens that highly express active, soluble target proteins to use in your research and product development. bit.ly/3pKqCLq #ProteinExpression
Experiencing difficulty expressing your #recombinantproteins? Our Pelican Expression Technology® platform optimizes high-yield #proteinexpression candidates to ensure solubility, proper folding, and functional activity. bit.ly/3JUWJ1N #PelicanExpressionTechnology
Congratulations to our partner @SerumInstIndia and their collaborators! Our PeliCRM197® carrier protein is a key component in this vaccine and many others that require a consistent and robust supply. Learn more: bit.ly/3ObauMj
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