Cooper et al. with CBATL at UWMC developed a machine learning approach to predict recipients at high risk for developing GVHD on factors at the time of OLT. Liver Transpl. 2021 Sep 29.doi: 10.1002/lt.26318. GVHD calculator: cbatl.shinyapps.io/GVHD/@AnalyticsCbatl#machinelearning
Little and CBATL observed pediatric DCD livers are underused but when transplanted have comparable survival to 18-40 year-old DCD donors. This survival is improved when transplanted into pediatric recipients. Pediatric DCD livers are a viable organ source for adults and children.
Clinical and Bio-Analytics Transplant Laboratory (CBATL) supported research to develop new protocols encouraging transplant programs to split more livers from younger donors saving young children and women from dying waiting for an organ.
Transplantation. 2020 Feb;104(2):299-307
Sibulesky and other CBATL members conducted research supporting the quality of aviremic hepatitis C positive (HCV NAT -) kidneys. Using these kidneys would result in more kidney transplants with the survival being the same as matched controls. #NAT- #Aviremic#kidney#transplant
Kling and other CBATL members observed that the number of donors with hepatitis C virus is increasing. They also observed a concomitant increase in the transplantation of kidneys and livers from aviremic donors. #kidney#liver#transplant#HCV
Kling and other members of CBATL in follow-up to previous research found there is no difference in 3-year patient and graft survival between kidneys from aviremic HCV donors (HCV Ab+ NAT –) and HCV negative donors (HCV Ab- Nat -). #HCV#kidney#Transplant
Butler et al. in a contemporary cohort of deceased donor kidney transplant recipients found no difference in graft loss from DCD compared to DBD grafts. These findings could increase the utilization of DCD kidneys helping to improve the shortage of donor kidneys. #kidney
Excellent survival in pediatric recipients undergoing liver transplantation with organs labeled Public Health Service (PHS) high-risk organs was the conclusion of a study by Dick et al. This may lead to increased use of these organs and decreased waitlist mortality. #transplant
Patients, families and liver transplant programs can be optimistic about retransplanting adults who received their primary transplant as children. Reyes et al. found no difference in survival rates for these patients being retransplanted as adults. onlinelibrary.wiley.com/doi/abs/10.111…
Clinical and Bio-Analytics Transplant Laboratory is a “think tank” to improve transplant healthcare. Our team strives to ask the “right questions”. We answers those questions using advanced machine learning techniques and “big data”. Visit us at our web-site.
#ATC2018Seattle Poster D191 reinforces that with induction therapy there is no need to obtain rapid therapeutic levels of tacrolimus in kidney transplantation. Analysis supported by CBATL.
#ATC2018Seattle CBATL supplied analysis for excellent poster (D18) updating that proper pharmacologic management of the donor improves graft survival and lowers cost by improving length of stay after transplantation.
Jorge Reyes, MD gave an enlightening talk on the surgical risks of liver retransplants in teens and young adults with some data supplied by CBATL. #ATC2018Seattle
Excellent presentation titled “Is KDPI Valid for Hepatitis C Aviremic Kidneys?” by Lena Sibulesky, MD from UW at #ATC2018Seattle using analysis supplied by CBATL.
Excited to attend #ATC2018Seattle. Will be viewing several presentations supported by our research analytic think tank- Clinical and Bio-Analytics Transplant Laboratory (CBATL in Seattle).
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