The Lewis Lab @PeterLewisLab
Chromatin biochemistry and genomics in development and cancer. @UWMadison @UWSMPH @BMC_UW TheLewisLab.net Wisconsin, USA Joined March 2019-
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The Lewis Lab retweeted
Our work "Aquarius helicase facilitates HIV-1 integration into R-loop enriched genomic regions," is out in @NatureMicrobiol nature.com/articles/s4156…
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The Lewis Lab retweeted
Really excited that our manuscript on Synovial Sarcoma is now online. Link to Open Access PDF: tinyurl.com/55bnssws A summary🧵 :
The Lewis Lab retweeted
@BeatrizGerFalc summarizing some of her latest work with the lab. #EZH2 controls cell plasticity in #ProstateCancer through coordination with activation of #translation and the RNA degrading protein #tristetraprolin @CPDR_Labs
The Lewis Lab retweeted
The Lewis Lab retweeted
The summer has been busy! Along with the move and a PhD defense, we have updated two preprints: biorxiv.org/content/10.110… and biorxiv.org/content/10.110…
The Lewis Lab retweeted
Hypertranscription state in early embryos that both shapes and is fostered by the three-dimensional genome organization, revealing an intimate interplay between chromatin structure and transcription @Nature @xielablife nature.com/articles/s4158…
The Lewis Lab retweeted
Online Now: Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation dlvr.it/TMRwWj
The Lewis Lab retweeted
This work was lead by PhD candidate Cecilia Gavilan, with contributions from multiple Iwase lab members. Check it out online! buff.ly/7XaD7cN
The Lewis Lab retweeted
Ever wondered what else SETD2 does beyond transcription? 🧬 Check out our new @NatureCellBio study. Awesome work from Abid Khan (@AbidKhanEpigen) showing how SETD2 moonlights to safeguard the genome during cell division. nature.com/articles/s4155…
The Lewis Lab retweeted
Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. sciencedirect.com/science/articl….
Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. sciencedirect.com/science/articl…. https://t.co/Xh5FVf5q6U
The Lewis Lab retweeted
Excited to share with you our latest preprint on SMARCA2/4 degraders! at the @UoDCeTPD in collaboration with #GeorgWinter´s lab. Here, we show how a Molecular Glue Degrader can covalently and redundantly recruit DCAF16 and FBXO22 to degrade SMARCA2/4 biorxiv.org/content/10.110…
The Lewis Lab retweeted
(1/n) Excited to share our new preprint! We uncover that RNA actively promotes nucleation and function of pathogenic condensates, amplifying locus-specific oncogenic transcription and promoting tumorigenesis. #epigenetics #condensates #cancer #RNA biorxiv.org/content/10.110…
The Lewis Lab retweeted
Please check out or new paper describing a novel relationship between DNMT3A and telomeres. It truly was a team effort ! Even better when your former @Goodell_Lab baymate @TheKingLab publishes in @CellStemCell in the same issue!
Please check out or new paper describing a novel relationship between DNMT3A and telomeres. It truly was a team effort ! Even better when your former @Goodell_Lab baymate @TheKingLab publishes in @CellStemCell in the same issue!
The Lewis Lab retweeted
An evolving landscape of PRC2–RNA interactions in chromatin regulation, by Aguilar @ragmau, Rosenberg, et al. now in print! Learn the latest about how Polycomb works with RNA in epigenetic regulation: nature.com/articles/s4158…
The Lewis Lab retweeted
Epigenetics Update - Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers bit.ly/44H3zCZ Robert K. McGinty (UNC) reproting in Mol Cell #Epigenetics #DNADemethylation #Chromatin --- Discover the breakthrough at epigenometech.com
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