Scott Rothbart @RothbartLab
Professor @VAInstitute. Chromatin biochemistry, cancer epigenetics, functional proteomics. rothbartlab.vai.org Grand Rapids, MI Joined November 2018-
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Big day for the David lab! 🎉 Our @MolecularCell paper is out today- huge congrats to first authors @IfeAkano & Jake Hebert for leading this beautiful study uncovering SMARCA3 as a novel H3 E3 ligase that shapes heterochromatin regulation in colorectal cancer 🤩
Big day for the David lab! 🎉 Our @MolecularCell paper is out today- huge congrats to first authors @IfeAkano & Jake Hebert for leading this beautiful study uncovering SMARCA3 as a novel H3 E3 ligase that shapes heterochromatin regulation in colorectal cancer 🤩
A person’s lifetime risk for #cancer may begin before they are even born, reports a paradigm-shifting study by Van Andel Institute scientists published in @NatureCancer. @PospisilikJ @Bi0lilla vai.org/cancer-risk-de…
Thrilled to share the results @Cancer_Cell of years of hard work to develop classifiers for all major TCGA cancer subtypes, enabling assessment of differential drug response among cancer subtypes in clinical trials. cell.com/cancer-cell/fu…
We have postdoc positions open to study epigenetic mechanisms contributing to resistance to chemo+immuno in TNBC, and projects related to epigenetic determinants of neurodevelopmental disorders. Feel free to reach out to me here/via email. Please like and repost!
Congratulations to Van Andel Institute’s Dr. Peter Jones, VAI and @hopkinskimmel's Dr. Stephen Baylin, and @HopkinsMedicine's Dr. Andrew Feinberg, who will receive the Harvey Prize for their groundbreaking work in cancer epigenetics! Read more: vai.org/harvey-prize
Online Now: DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states dlvr.it/TGZ732
Congratulations to the authors @RothbartLab, shows the role of UHRF1 in the redistribution of H3K9me3 following DNA hypomethylation, a lingering question in the field and may have implications for the field of aging. cell.com/molecular-cell…
Two new papers from the lab to end the year! Will be posting about them both at the new place in the coming weeks. @RothbartLab.bsky.social Come join us - it’s great! #SciCommBackAgain
Time to move. See you all on Bluesky: @helink.bsky.social Let's work on getting our respective institutions and our colleagues to move as well. There is an exponential increase in members on Bluesky!! theguardian.com/media/2024/nov…
If you are interested in a faculty position in the heart of metabolism, at one of strongest and most supportive institutes focused on metabolism, epigenetics, neurodegeneration and more, VAI is recruiting at all levels! vai.wd1.myworkdayjobs.com/en-US/VAICaree…
Great place to post doc @VAInstitute
Just 2 postdocs from @DrBrianStrahl’s lab (current: me; former: @RothbartLab) with their mentor. Looking forward to joining Scott on the former postdoc/current PI list by the next #BioMethylSRC
Registration is still open for this super exciting meeting! ⭐️Unbelievable lineup of #epigenetics & #aging speakers ⭐️Opportunities for short talks ⭐️New pre-meeting dedicated to trainees w/ extra opportunities for career development & 1:1 with PIs ⭐️Special awards available!
Registration is still open for this super exciting meeting! ⭐️Unbelievable lineup of #epigenetics & #aging speakers ⭐️Opportunities for short talks ⭐️New pre-meeting dedicated to trainees w/ extra opportunities for career development & 1:1 with PIs ⭐️Special awards available!
What's new and what's next in cancer epigenetics research? Join us for the 2024 VAI Epigenetics Symposium. Our allstar speaker lineup will highlight the latest advances with a focus on mechanisms and therapeutic applications. Registration closes tomorrow! vai.org/event/vai-epig…
Registration closes May 10 for the VAI Epigenomics Workshop. This 3-day, hands-on, problem-based experience will immerse PhD students in the latest epigenomics research and techniques. Please share with anyone who might be interested! vai.org/event/vai-epig…
Holes in the patio umbrella on the terrace @VAInstitute produced hundreds of tiny eclipse shadows for us to enjoy. @BurtonNick was right place right time to catch some on his shirt too!
A pair of medications that make malignant cells act as if they have a virus could hold promise for treating #colorectalcancer & other solid tumors, according to a new preclinical study by scientists @RothbartLab. #colorectalcancerAwarenessMonth vai.org/rothbart-crc-s…
"The unmet potential of DNA methyltransferase inhibition therapy in patients with solid tumors underscores the importance of our findings." Congrats to @AmericanCancer grantee @RothbartLab for this this exciting study as we come to the end of #ColorectalCancerAwarenessMonth!
"The unmet potential of DNA methyltransferase inhibition therapy in patients with solid tumors underscores the importance of our findings." Congrats to @AmericanCancer grantee @RothbartLab for this this exciting study as we come to the end of #ColorectalCancerAwarenessMonth!
New paper from the lab reveals a link between epigenetic therapy-induced viral mimicry and NFAT:AP1 signaling. Rationale for combining DNMT and EZH2 inhibitors in colon cancer. Thankful to @theNCI and @ACS_Research for supporting our work! science.org/doi/10.1126/sc…

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Epigenetics Congress @EGC_2026
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Carlos A. Pinzón Art... @carlosapinzona
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Van Andel Institute (... @VAInstitute
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689 Followers 367 Following Professor @UWMadison School of Medicine and Public Health | chromatin biochemistry, cancer genomics, epigenetic inheritance | Lab:@PeterLewisLab
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Shiv Grewal @grewalsh
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Raphaël Pantier @R_Pantier
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Anja Groth 🇺🇦 @groth_anja
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Geneviève Almouzni @GAlmouzni
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Nadia Dehghani @DrNDehghani
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Arkajit De (he/him/hi... @arkajit_de
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@CEI-FCCC @CeiFccc
397 Followers 315 Following Cancer Epigenetics Institute- Bringing Discovery to the Patient
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77 Followers 182 Following PhD Student, Indiana University School of Medicine Biochemistry Cornett Lab Lysine Methylation
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