Ryan M. Carr @RMCarrLab
Medical Oncologist | Cancer Biologist "Nothing in biology makes sense except in the light of evolution" @MayoClinic @MayoCancerCare carr-lab.com Rochester, Minnesota Joined May 2009-
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Ryan M. Carr retweeted
Woah! Can’t even remember how long back this was! Lot of the #mayocrew still here! @UDuraniMD @hampel_p #moritzbinder @JithmaA @RMCarrLab has defected to the solid tumour world and I am sure @E_D_Bezerra isn’t complaining about the weather anymore! #ASH24
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Ryan M. Carr retweeted
🚀In our latest 📜we explored the molecular characteristics of #KRAS wt #PDAC and found actionable genetic variants. ➡️TFG-MET rearrangement showed response to a c-MET inhibitor. Precision medicine #futureisnow! 🔬 @RMCarrLab @AMansfieldMD @GIcancerDoc bit.ly/4bgHBHM
Transcriptomic analysis of a cohort of KRAS wildtype PDAC reveals enrichment of KRAS signaling in a significant subset. KRAS (on) inhibitors may have utility in these patients. mdpi.com/2787246 #mdpicancers via @Cancers_MDPI
Always enjoy @DBasanta presenting on math modeling of cancer. This time, models evolvability. #CancerEvoEco24
Thought provoking presentation from @mariasecrier on cell intrinsic and microenvironmental constraints of EMT. #CancerEvoEco24
Beautiful work from @LauraMachesky demonstrating the effect of mechanosensing and other unique biophysical properties on pancreatic cancer cell metabolic plasticity. #CancerEvoEco24
Learn more at ClinicalTrials.gov NCT05726864 Would you like to participate? Contact us: Dr. Ryan Carr at: carr dot ryan at mayo.edu Preston Buechler at: (507) 422-5917 or buechler dot preston at mayo.edu
Please consider supporting my awesome colleague, Elise Novo and her family during this challenging time. gofund.me/f0bffac8
Ryan M. Carr retweeted
Moffitt's best differentiator is the ability to work on math models w/ clinical translational potential: medrxiv.org/content/10.110… mathematical models as part of the decision-making process within a tumor board -- an "evolutionary tumor board:
Moffitt's best differentiator is the ability to work on math models w/ clinical translational potential: medrxiv.org/content/10.110… mathematical models as part of the decision-making process within a tumor board -- an "evolutionary tumor board:
Ryan M. Carr retweeted
Is biological complexity predictable? Can genes explain development? No, due to the emergent nature of the genotype-phenotype map: higher-level properties are irreducible to lower-level ones. Here's my drawing with CH Waddington as a demon. @manlius84 @sanewman1 @drmichaellevin
Getting festive! @ Mayo Clinic Rochester MN instagram.com/p/Cl9np3Pvyl2/…
Ryan M. Carr retweeted
All you wanted to know about genomic testing and ctDNA but we’re too afraid to ask… Dr. @Ryan_M_Carr sheds light on the currently used panels of genomic testing.
Yes, join the AACR Cancer Evolution Working Group! New area of study aims to use tumor evolution to fight cancer aacrmeetingnews.org/news/new-area-…
DYNAMIC - Circulating Tumor DNA to decide Adjuvant Chemo in Stage II Col... youtu.be/QxOBIi7I2BU via @YouTube - compelling criticisms here, had some questions re: oxaliplatin use myself.
Ryan M. Carr retweeted
We’re proud to support 97 promising physicians with their work to help patients through quality #cancerresearch in clinical #oncology. Meet the 2022 recipients of the Conquer Cancer Young Investigator Awards (YIA)!
Ryan M. Carr retweeted
Grateful to be able to work with such a great team. Thank you @NatureComms for accepting two papers on #CMML …from @MayoCancerCare | Rare diseases are not rare for those affected by them #notMDS #notMPN #CMML @MoritzBinderMD @Ryan_M_Carr @a_mangaonkar @MayoClinicCIM
Grateful to be able to work with such a great team. Thank you @NatureComms for accepting two papers on #CMML …from @MayoCancerCare | Rare diseases are not rare for those affected by them #notMDS #notMPN #CMML @MoritzBinderMD @Ryan_M_Carr @a_mangaonkar @MayoClinicCIM
Ryan M. Carr retweeted
I am incredibly excited to share our preprint ‘Somatic mutation rates scale with lifespan across mammals’In this paper we provide an unprecedented description of somatic mutation across mammals. biorxiv.org/content/10.110… An illustrated tweetorial…[1/17]
Wonderful! Rotating through Gyn Onc clinic, I've always thought evolutionary therapy could be very effective in preventing emergence of platinum resistance in high grade serous ovarian cancer - truly individualized medicine. @MayoCancerCare @MayoClinicCIM
Wonderful! Rotating through Gyn Onc clinic, I've always thought evolutionary therapy could be very effective in preventing emergence of platinum resistance in high grade serous ovarian cancer - truly individualized medicine. @MayoCancerCare @MayoClinicCIM
Another fascinating pre-print. Comparative mutagenesis via WGS on intestinal crypts across 16 mammalian species. Despite substantial variation in lifespan/body mass, somatic mutation burden, and therefore mutation rate, scales with organismal lifespan. biorxiv.org/content/10.110…
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541 Followers 1K Following NMF Is dedicated to providing comfort and relief for those affected by #pancreaticcancer, while raising awareness and funding research #PreventDetectCure
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