It has been 2 years since the 1st detection of #SARSCoV2 and yet the #pandemic shows little signs of slowing down, as seen most recently through the emergence of #omicron and its surprisingly large No. of mutations. How surprising is that though? A thread. biorxiv.org/content/10.110…

Currently, #variants with higher transmissibility and/or immune evasion (antibody escape) have supplanted the founder strain Wu-Hu-1.

While antibodies from vaccinations and infections induce highly neutralising antibodies against the RBD, the RBD has proven to be incredibly versatile, as shown by the pioneering work of @jbloom_lab @tylernstarr @AllieGreaney in their landmark papers @CELL and @ScienceMagazine.