Repare Therapeutics @RepareRx
Repare is a leading precision oncology company enabled by our proprietary synthetic lethality approach to the discovery and development of novel therapeutics. reparerx.com Montréal, Québec Joined June 2017-
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We are thrilled the first patient has been dosed with the first combination of PKMYT1i + WEE1i to enter the clinic. We are grateful to collaborate with @DebiopharmNews in this shared mission to deliver innovative precision medicine therapies to patients. lnkd.in/enqBacnx
Meet with @RepareRx's management team at the 2024 @bloomburton Healthcare Investor Conference on Tuesday for 1x1s and a company presentation. We look forward to connecting in person! Webcast can be found here: lnkd.in/eyepZbQJ #BBHIC2024 #syntheticlethality $RPTX
Please join us at a Major Symposium Session at the #AACR24 Annual Meeting on lunresertib and combinations with ATR or WEE1 inhibitors “Targeting CDK1 Activation in Cancer”, presented by Jordan Young, Senior Director, Oncology Discovery at @RepareRx. #syntheticlethality $RPTX
That's a wrap with the @TDCowen 44th Annual Health Care Conference in which Repare's EVP & Chief Medical Officer, Maria Koehler MD PhD, spoke as a panelist on the Gynecological Cancers Panel. Thank you for listening: lnkd.in/gZVwWjmC #TDCowenHealthCare #precisiononcology
We announced Q4 & FY 2023 financial results and provided a business update. As leaders and innovators in #PKMYT1 inhibition, we look forward to data readouts across all ongoing lunresertib trials in 2024 and begin a combo trial with @DebiopharmNews. lnkd.in/eKTV-FRr $RPTX
Don't miss Ale's presentation on Saturday at the 6th DNA Repair/Replication Structures and Cancer Conference. He is speaking about the power of #syntheticlethality, after Dr. Timothy Yap's presentation on Targeting ATR in the Clinic. #DRRSC24
We are proud to announce first patient dosing in our Ph1 LIONS #clinicaltrial of RP-1664, a potential first-in-class, oral PLK4 inhibitor, designed to harness the #syntheticlethal relationship with TRIM37 amplification or O/E in #solidtumors. lnkd.in/eSsZkAGa $RPTX
At Repare we’re committed to discovering and developing highly targeted #cancertherapies for patients. With #WorldCancerDay approaching, we recognize and support the global community in the mission to #CloseTheCareGap to create easier access to vital cancer services. #FightCancer
"If you want to go far, go together." We celebrated the beginning of our clinical collaboration with @DebiopharmNews at #JPM2024 this week. This partnership accelerates our shared mission to transform the landscape of cancer treatment and improve patient outcomes. #PKMYT1 #WEE1
Today, we provided a corporate update and highlighted key anticipated milestones. 2024 will be a substantial year for Repare as we aim to expand our pipeline to four clinical programs and expect multiple readouts from ongoing lunresertib combinations. lnkd.in/e59RZrBh
Today, Repare disclosed the target of the RP-1664 development program and reported comprehensive preclinical data for RP-1664 and RP-3467. We’re hosting a conference call & webcast at 8 a.m. ET today to discuss the data. Full press release: bit.ly/47yXGGp
Tomorrow, we're hosting a conference call and webcast call focused on our emerging late-stage pipeline programs, RP-1664 and RP-3467. Tune in here at 8am ET: bit.ly/3FPVOxj
Join us tomorrow at the @Stifel 2023 Healthcare Conference, where members of Repare’s management team will participate in a fireside chat. Watch the webcast here: bit.ly/3ugACxD
Today, we announced our third quarter 2023 financial results and provided a business update. Full press release with additional details: bit.ly/49qKl4L #precisiononcology #syntheticlethality $RPTX
Next Wednesday (11/15), Repare will host a conference call and webcast to present the latest data from its ongoing preclinical programs, RP-1664 and RP-3467, a newly designated Polθ inhibitor. Tune in here: bit.ly/49pOxBB
Members of Repare’s management team will participate in the @Stifel 2023 Healthcare Conference and the @Piper_Sandler 35th Annual Healthcare Conference this month. We look forward to connecting in person! Webcasts can be found here: bit.ly/3FMGmSr
Daniel Durocher @durocher1
4K Followers 907 Following Lunenfeld-Tanenbaum Research Institute & U of Toronto // Lab tweets @durocherlab // Founder of @RepareRx // DNA repair, Synthetic lethality, Induced proximityStephanie Panier @spanier55
944 Followers 559 Following Group Leader at Max Planck Institute for Biology of Ageing and at the University of Cologne. Studying how cells repair DNA damage.Agnel Sfeir @AgnelSfeir
2K Followers 395 Following Scientist during the day. Rock climber, scuba diving, sky diving during off hours. Prof. @MSKCC and co-founder of @RPTX. 🇱🇧+🇺🇸 in NYCAlberto Ciccia @CicciaAlberto
2K Followers 1K Following Scientist at Columbia University interested in genome stability and genome editing | https://t.co/eX2AJeJQtLdurocherlab @durocherlab
3K Followers 2K Following We are located at the Lunenfeld-Tanenbaum Research Institute and work on understanding the fascinating processes underlying genome integrityJacob Corn @jcornlab
5K Followers 508 Following Genome editing, functional genomics, and cells figuring out how to eat themselves without dying. Professor of Genome Biology at ETH Zürich.Dheva Setiaputra @biochemDheva
418 Followers 194 Following Assistant Professor at SFU | Molecular mechanisms of the DNA damage response | Enjoys long sits on the couch | Views + good jokes my own, bad jokes yours |Sarah R. Hengel Ph.D. @science_SRH
4K Followers 1K Following Human Being | She/her| Mother of 🐕 | 🌈 | Lyme Disease Survivor | Personal account | tik tok : sarahtheproteinscientist | opinions my own| rt means supportTony Cesare @tonycesare4
543 Followers 673 Following Researcher studying genome stability. Head coach Wests Boomers U14 and U10 Baseball. Views are my own. For lab news see @TheCesareLab.Robert W. Sobol @rwsobol
3K Followers 5K Following Dean’s Professor of Cancer Research & Associate Director Basic Research; Legorreta Cancer Center, Brown University - studying DNA damage response in cancerPatrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast Grantsmichele pagano @paganolab
2K Followers 910 Following Studying the molecular mechanisms underlying the degradation of cellular regulatory proteins by the ubiquitin system and inform about cancer vulnerabilitiesArne N. Kousholt @ArneKousholt
456 Followers 770 Following CEO and Founder, VUS Dx. Functional assays to help guide personalised treatment for cancer patients. DNA repair. CRISPR. Acquired drug resistance.Haico van Attikum @ha.. @haicovanattikum
2K Followers 698 Following Full professor at Leiden University Medical Center. Studying DNA repair in chromatin and its link to human disease.Ben Kleinstiver @BKleinstiver
4K Followers 670 Following Associate Professor @CGM_MGH at @MGH_RI & @HarvardMed Genome editing / Protein eng. / Molecular medicine 🇨🇦🧬 Kayden-Lambert MGH Research Scholar '23-28Sharon B. Cantor @CantorLab
2K Followers 834 Following Professor studying DNA replication and role in cancer, chemoresistance, and developmental diseasesPierre Caron @CaronPierre13
1K Followers 3K Following @IBS_Grenoble @IRIG_Grenoble @cea_grenoble | CNRS researcher | @Prelights | @EDRA_WebinarsAmisha @amishaminju
78 Followers 1K Following PhD Student Department of Human Genetics McGill UniversityDSI, a PLG Company @DSInPharmatics
314 Followers 1K Following DSI is a full service CMC Drug Development Consulting Firm, assisting emerging Biotech and Pharma sponsors with CMC, Regulatory and QA for NCEs & BiologicsAlex @AlexAtYUL
6 Followers 5 FollowingDavid Krochmal @solarenergydave
8 Followers 50 Following Energy Consultant Solar Dave, LLC Solar energy for businesses and residential properties.Eric Chih-Chao Liang @EricCCLiang
110 Followers 265 Following Research Scientist | Biochemist and Structural Biologist | PostDoc at @TheCrick | DNA Repair & Recombination | PhD from @UniofOxfordTammy Kapur @KapurTammy
0 Followers 7 FollowingCancer Research Horiz.. @CR_Horizons
2K Followers 2K Following We are @CR_UK’s #innovation arm. We strengthen #academia & #industry collaboration, bridging the gap between research and the market.Thorben Huth @ThorbenGorm
42 Followers 236 Following Postdoc at UKHD | Biochemist and Cancer Scientist | CRISPR Aficionado | Outdoor Lover and Scoutkavita_gala @KavitaGala
369 Followers 404 FollowingJonathan Lee @ColdCasanova1
39 Followers 286 FollowingPriya Chudasama @priyachudasama5
551 Followers 208 Following Translational sarcoma researcher @NCT_HD and @DKFZ. Interested in functional and structural genomics in sarcoma, mentoring, mountain hikes and food.Stavroula Tsaridou @Stavroula_Tsar
77 Followers 289 Following PhD student of the Medical Oncology Department of @UMCG studying DNA damage responses. 🧬🔬Megan E. Kelley, PhD @MeganEKelley
746 Followers 2K Following Postdoc @MSKCancerCenter in https://t.co/FldT6CqBJG | former @KapoorLab_RU | interested in #CancerBiology #DNARepair #DrugResistance #Mitosis | she/herTomas Goncalves @Tomas1Goncalves
19 Followers 44 Following DPhil student @MRC_WIMM in the Radcliffe Department of Medicine. MSci Human Genetics @UCL. I study how cancers maintain their telomeres to divide indefinitelyJiajun Gu @GuJiajun714
30 Followers 18 FollowingBenoit Larose🩺💉.. @blarose33
1K Followers 3K Following PDG BioQuébec. Voir mon profil LinkedIn has it all... https://t.co/nj5hqMqHRVJeff J. Grice @iamJ2GRICE
2K Followers 870 Following Head of Marketplace Ops | Startup Investor | Tesla & SpaceX Investor | Laguna Beach🛬Detroit #Tesla #SpaceX #AI #Housing #Tech #web3 🇺🇸The Cancer Dependency.. @CancerDepMap
3K Followers 273 Following We construct systematic key datasets, analytical and visualization tools to accelerate precision cancer medicine #depmap #syntheticlethal #drugtargetsCynthia bernier @CBY12T23
0 Followers 5 FollowingLenno Krenning @KrenningLenno
28 Followers 40 FollowingMohammad Daud @itsmudaud
96 Followers 401 Following Molecular Genetics @UofT current sciencegasm: gene editing, plant immunity, mtDNA quality controlFlorin-Mihai Danciu @FlorinMihaiMik
213 Followers 649 FollowingMadeleine King @madbking5
93 Followers 289 Following Ph.D. candidate in the @LapinaiteRNALab at Arizona State University | Precise Genome Editing, RNA Biologist, Protein Engineering, CRISPR-Cas9Christopher Johnny @ChrisJScience
135 Followers 155 Following Harvard College '18 BA Chemistry, Chinese language citation// University of Pennsylvania '24 PhD ChemistryThe Jacobian Ghost @JacobianGhost
1 Followers 72 FollowingKsenia G. Kolobynina @KKolobynina
24 Followers 191 Following PhD student at Cardoso Lab, TU Darmstadt Science interests: DNA repair, DNA replication, chromatin, senescenceNazareno Bona @NazarenoBona
221 Followers 256 Following Research Associate @Cambridge_Uni | Transposable elements 🧬 | College Research Associate @SidneySussex | Former PhD student @MRC_LMBJ @wardenofthewest
72 Followers 262 FollowingAugusto Chaves Murrie.. @AugustoChavesM
20 Followers 58 Following Lab Manager in the Hamperl lab at @epigeneticsHMGU @HelmholtzMunich Former student at University of Buenos Aires Working on transcription replication conflictsDale Ramsden @dale_ramsden
392 Followers 354 Following interested in genome stability and end joining pathways for double strand break repair. @UNC, @UNC_LinebergerTom Watkins @tbkwatkins
986 Followers 3K Following Postdoc @mischellab | incoming PGY1 @StanfordPath Physician Scientist Incubator Track | visiting scientist @SwantonLab | @UCL_MBPhD alumAnnabel Quinet @AnnabelQuinet
619 Followers 460 Following Group Leader @INSERM @CEA_Jacob_ fascinated about the links between DNA replication, genome stability and cancer. Eclectic Brazilian carioca, momDr B Ciani - https://.. @BCiani
572 Followers 946 Following Misplaced chemist doing biology. Dog lover. In Yorkshire fro Rome She/her. If I tweet, it's my own opinion. @[email protected];@drbciani.bsky.socialLauren Evans @laur_tay_evs
218 Followers 181 Following A journey of a thousand miles must begin with a single step (she/her)Darshika Bohra @SanskariMarwadi
185 Followers 348 Following Waddling through grad school one DNA damage at a time/🔬chromatin organization in context of damage/LLPS/Always up for an espresso and some good old running 🏃Paul & Virginie - Cen.. @CentrioleLab
4K Followers 2K Following Paul Guichard & Virginie Hamel Lab @Biologie_UNIGE #cryoEM and #cryoET❄️ #UExM ⚗️ #cellbiology #TeamTomo @[email protected]Catalina @Catalina12_10
2 Followers 41 FollowingHola @mostmodest2
409 Followers 3K FollowingAnanya Acharya @AnanyaAcharya26
191 Followers 653 Following PhD @Cejkalab, Institute for Research in Biomedicine @Bellinzonairb, Department of Biology, ETH Zurich @ETH_DBIOL; BS-MS IISER Kolkata @iiserkol.Marek Adamowicz @MarekAdamow
105 Followers 136 Following Research scientist working with BER/PARPs/Transcription/DSBs. Postdoc in @BoultonLab. PhD with @FdAdF66.KJ Patel CAM-OX trave.. @ketanpatelimmo1
1K Followers 2K Following Aldehyde enthusiast in research and consumptionLuca Fava @LucaFava14
478 Followers 377 Following Team leader and associate professor at CIBIO, University of Trento. Interested in how cells sense and transduce malfunctions of the cell division cycleDr Hannah Bolland @onco_hannah
931 Followers 2K Following Cancer biologist, lover of tumour hypoxia, peroxisomes, unfolded protein response. Junior Group Leader/Surrey Future Fellow @UniOfSurrey @SurreyVetおっと @GunFamily36
84 Followers 278 Following 妻 卵巣がん 漿液性ステージ3 BRCA陽性。情報収集アカウント。TC6クール後アバスチン+リムパーザ。ハイパーサーミア、高濃度ビタミンC、遺伝子治療、アルテミシニンなど併用。Sidrit Uruci (Sid) @UruciSidrit
246 Followers 380 Following PhD in @luijsterburglab at @LUMC_Leiden, previously in @Tanejalab at @ErasmusMC. Science lover, DNA enthusiast. European child 🇪🇺🇳🇱🇮🇹🇦🇱🏳️🌈Scott Keeney @Spo11Rulz
3K Followers 1K Following Scientist. Meiosis nerd. 🏳️🌈 Queer as a $3 bill. He/him. No birds were harmed in the making of these tweets. @[email protected]Daniel Durocher @durocher1
4K Followers 907 Following Lunenfeld-Tanenbaum Research Institute & U of Toronto // Lab tweets @durocherlab // Founder of @RepareRx // DNA repair, Synthetic lethality, Induced proximityAgnel Sfeir @AgnelSfeir
2K Followers 395 Following Scientist during the day. Rock climber, scuba diving, sky diving during off hours. Prof. @MSKCC and co-founder of @RPTX. 🇱🇧+🇺🇸 in NYCdurocherlab @durocherlab
3K Followers 2K Following We are located at the Lunenfeld-Tanenbaum Research Institute and work on understanding the fascinating processes underlying genome integrityBIOTECanada @BIOTECanada
7K Followers 2K Following All about Canadian biotechnology from the national industry association.Nasdaq Exchange @NasdaqExchange
762K Followers 8K Following At @Nasdaq, we power stronger economies, create more equitable opportunities, and contribute to a more sustainable world. #NasdaqListed@RepareRx See you at the Gold Leaf Awards on September 27th!
Exciting data today by Dr. Tim Yap + @RepareRx in #AACR2023 plenary session. Camonsertib, partnered with @Roche, continues to show high promise for patients with ovarian and other cancers. 👏Drs Maria Koehler, Mike Zinda and their teams! #precisiononcology #syntheticlethality
Today at #AACR23 Clinical Trials Plenary Session, Repare disclosed initial data from our ongoing Phase 1/2 TRESR and ATTACC clinical trials evaluating camonsertib in combination with three PARP inhibitors in patients with #solidtumors. Full presentation: tinyurl.com/ywvz72v4
Broad's @CancerDepMap Consortium, is entering a new phase, with 19 biopharma partners, and accelerating its research into tumor vulnerabilities and identifying key biomarkers. broad.io/DepMap-News-01…
We just finished a very successful lab retreat - the first one since the pre-pandemic times. It was great to be together for great science, nice dinner, chilly fire pit and some pretty good memes...
.@NasdaqExchange congratulates #NasdaqListed @RepareRx on its license and collaboration deal with @Roche. 🎉 The collaboration allows for the development of camonsertib (RP-3500) with potential to expand development into additional tumors and multiple combination studies.
Our work on the identification of the PKMYT1 kinase (aka Myt1) as a vulnerability in cyclin E gene-amplfied cells is (finally) published! nature.com/articles/s4158… [paper is OA]. This work was a close collaboration with @RepareRx 1/5
+1000000, one was my mom 💔
A day to remember the many wonderful women that lost the battle to breast cancer. And for those that are fighting today -> Keep strong. You´re not alone. BIG HUG. #worldbreastcancerday
Thanks, #NASDAQ for a reminder that a year has passed since @RepareRx IPO. 2 clinical programs and an incredible year of progress later by our amazing team, feels like the blink of an eye. #precisiononcology #syntheticlethality
This one means a lot to me as it is the first target we discovered through our screens for which we developed a drug that we bring to the clinic. Thank you to the patients in this study and crossing fingers and toes that we can make a difference! 🤞
We’re thrilled to have dosed the first patient in our Phase 1 RP-6306 trial! Click this link to read our full press release: ir.reparerx.com/news-releases/…
The second Repare drug enters the clinic. Congrats to the $RPTX @RepareRx team.
We’re thrilled to have dosed the first patient in our Phase 1 RP-6306 trial! Click this link to read our full press release: ir.reparerx.com/news-releases/…
Today, I am one proud @RepareRx team member. So happy for my friend @durocher1 , his baby will make a difference in CCNE high tumors. The brilliance of @MichaelZinda and Maria Koehler will make this happen. Kudos to @JTFYoung , David Gallo, Jimmy, Gary, and the rest of the team
New preprint from the @durocherlab ! In close collaboration with our colleagues at @RepareRx we report that inhibition of the kinase PKMYT1 is lethal in cells with cyclin E (CCNE1) gene amplification. biorxiv.org/content/10.110… 1/7
New preprint from the @durocherlab ! In close collaboration with our colleagues at @RepareRx we report that inhibition of the kinase PKMYT1 is lethal in cells with cyclin E (CCNE1) gene amplification. biorxiv.org/content/10.110… 1/7
Jobs for enthusiasts of science, data science and willing to make a dent (or a double-strand break) in cancer. Well funded and collaborating with top academic groups on genomics, synthetic lethality and CRISPR screens. @RepareRx lnkd.in/dpKEkXW lnkd.in/dMXDqcH
Proud of this initiative from my colleagues at @RepareRx in partnership with @nsbeboston ! A similar initiative is being set up in MTL too.
Repare Therapeutics partners with NSBE Boston to promote STEM Initiatives - mailchi.mp/nsbeboston/jb-…
Repare Therapeutics partners with NSBE Boston to promote STEM Initiatives - mailchi.mp/nsbeboston/jb-…